<abstract xmlns="http://www.w3.org/1999/xhtml">

<sec><h3>Objective</h3>
<p>Our goal was to characterize a cohort of heart failure patients with and without COVID-19 in terms of demographics, comorbid conditions, treatment regimens, lab test results and outcome.</p>
</sec>
<sec><h3>Methods</h3>
<p>We performed a retrospective, unicentric, cohort study on consecutive patients admitted to our department between September and December 2021.</p>
</sec>
<sec><h3>Results</h3>
<p>We enrolled a total of 76 HF patients – 65.3% COVID-19 (+). The median age was 72 years with a female predominance (59.2%). The median length of hospitalization was 13 days, longer for COVID-19 (+). Only 20.7% of all patients were fully vaccinated. COVID-19 (+) patients had higher ICU admission rates and mortality (in-hospital and at follow-up). The most common associated conditions were HTN (78.9%), T2DM (38.2%), cancer (18.4%), CAD (17.1%), late-stage CKD (16.7%), AF (14.5%) and stroke (11.8%). Patients with a history of stroke were more likely to require ICU management. At-home treatment with ACEi/ARB/ARNi made no difference for COVID-19 severity (p = 0.393), mechanical ventilation (p = 0.101) or mortality (in-hospital: p = 0.316; follow-up: p = 0.563); however, ICU admission rates were lower in these patients (p = 0.023).</p>
</sec>
<sec><h3>Conclusion</h3>
<p>Heart failure with preserved ejection fraction and low symptom severity were common findings among COVID-19 positive patients. However, COVID-19 positive patients were hospitalized for longer, required more ICU care and had higher mortality both in-hospital and at follow-up.</p>
</sec>
</abstract>

Objective
Our goal was to characterize a cohort of heart failure patients with and without COVID-19 in terms of demographics, comorbid conditions, treatment regimens, lab test results and outcome.

Methods
We performed a retrospective, unicentric, cohort study on consecutive patients admitted to our department between September and December 2021.

Results
We enrolled a total of 76 HF patients – 65.3% COVID-19 (+). The median age was 72 years with a female predominance (59.2%). The median length of hospitalization was 13 days, longer for COVID-19 (+). Only 20.7% of all patients were fully vaccinated. COVID-19 (+) patients had higher ICU admission rates and mortality (in-hospital and at follow-up). The most common associated conditions were HTN (78.9%), T2DM (38.2%), cancer (18.4%), CAD (17.1%), late-stage CKD (16.7%), AF (14.5%) and stroke (11.8%). Patients with a history of stroke were more likely to require ICU management. At-home treatment with ACEi/ARB/ARNi made no difference for COVID-19 severity (p = 0.393), mechanical ventilation (p = 0.101) or mortality (in-hospital: p = 0.316; follow-up: p = 0.563); however, ICU admission rates were lower in these patients (p = 0.023).

Conclusion
Heart failure with preserved ejection fraction and low symptom severity were common findings among COVID-19 positive patients. However, COVID-19 positive patients were hospitalized for longer, required more ICU care and had higher mortality both in-hospital and at follow-up.

Acute Decompensated Heart Failure in Patients With and Without COVID-19 — The Experience of a Romanian Center

Internal Medicine and Cardiology Department

Carol Davila University of Medicine and Pharmacy

Romanian Journal of Cardiology

This work is licensed under the Creative Commons Attribution 4.0 International License.

Objective
Our goal was to characterize a cohort of heart failure patients with and without COVID-19 in terms of demographics, comorbid conditions, treatment...

Acute Decompensated Heart Failure in Patients With and Without COVID-19 — The Experience of a Romanian Center

Article Category: Original Article

Publié en ligne: 11 nov. 2022

Pages: 149 - 155

DOI: https://doi.org/10.2478/rjc-2022-0024

Mots clés
heart failure, HFpEF, heart failure comorbidities, heart failure treatment, COVID-19, ICU admission, COVID-19 mortality, ACEI

© 2022 Ana-Maria Vintilă et al., published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.

Acute Decompensated Heart Failure in Patients With and Without COVID-19 — The Experience of a Romanian Center

Article Category: Original Article

Publié en ligne: 11 nov. 2022

Pages: 149 - 155

DOI: https://doi.org/10.2478/rjc-2022-0024

Mots clésheart failure, HFpEF, heart failure comorbidities, heart failure treatment, COVID-19, ICU admission, COVID-19 mortality, ACEI

© 2022 Ana-Maria Vintilă et al., published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.

Mots clés
heart failure, HFpEF, heart failure comorbidities, heart failure treatment, COVID-19, ICU admission, COVID-19 mortality, ACEI