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Effect of glomerular filtration rate on in-hospital complications

Outcome variable Group 1n = 116 Group 2n = 120 Group 3n = 115 p Value
ALE and CS 10.3% 5.8% 0.9% < 0.05
Pulseless VT or VF 2.6% 3.3% 0.9% > 0.05
AF or AFL 12.1% 5.8% 3.5% < 0.05
In-hospital pneumonia 13.8% 6.7% 4.3% < 0.05
In-hospital death 3.4% 0.8% 0 >0.05
CIN needing dialysis 1.7% 0 0 > 0.05

Baseline comparability of the study groups

Variables Group 1n = 116 Group 2n = 120 Group 3n=115 p-value
GFR (ml/min/1.73 m2) 48.2 ± 10.4 74.7 ± 8.7 104.1 ±14.6 < 0.001
Age, years 66.2±10.1 66.2±9.1 64.5±6.8 0.23
Male 64.7% 65% 75.7% 0.12
Hypertension 68.1% 69.2% 63.5% 0.62
Diabetes 22.4% 23.3% 24.3% 0.94
PMI 11.2% 10% 4.3% 0.14
Anterior STEMI 46.6% 42.5% 40% 0.6
Patients with multivessel disease 46.6% 52.5% 41.7% 0.25
Patients who underwent complete revascularisation 7.8% 13.3% 10.4% 0.38
Killip > II class at the time of admission 3.4% 2.5% 0.9% 0.41
LV EF 39.1±8.5% 44.5±3.2% 41.9±6.8% 0.16
Used contrast volume (ml) 234.8±65.1 231.7±63.7 224.5±23 0.34

The groups were comparable in terms of drugs received

Drugs received Group 1n = 116 Group 2n = 120 Group 3n = 115 p-value
Aspirin 100% 100% 100%
Clopidogrel 100% 100% 100%
Heparin and LMWHs 100% 100% 100%
Statins 100% 100% 100%
B-blockers 83.6% 84.2% 88.7% 0.49
ACE inhibitors or ARBs 83.6% 88.3% 91.3% 0.2
Aldosterone antagonists 33.6% 34.2% 29.6% 0.72
Calcium antagonist 22.4% 20.8% 13.9% 0.22
Loop diuretics 38.8% 35.8% 32.2% 0.58