<abstract xmlns="http://www.w3.org/1999/xhtml">

<sec><h3>Background</h3>
<p>Left main percutaneous coronary intervention (PCI) has been established as an effective and safe treatment option for left main coronary artery disease. There are data suggesting that different stent platforms can impact the outcomes after left main PCI. The aim of current study was to compare the four-year outcomes of patients with left main stenosis treated by PCI with a balloon-expandable stent or a self-apposing stent.</p>
</sec>
<sec><h3>Methods and Results</h3>
<p>A total of 146 patients with left main stenosis treated by PCI were included, of which 84 (57.5%) had balloon-expandable stents (Group A) and 62 (42.5%) had self-apposing stents (Group B). Baseline SYNTAX scores were higher in Group A than in Group B. Proximal optimization technique was used more often in Group A (45.2% in Group B vs 81.4% in Group A, p&lt;0.001). The same observations were made for kissing balloon postdilation (30.6% Group B vs 62.7% in Group A, p&lt;0.001).</p>
<p>Procedural success with TIMI 3 flow was achieved in similar proportions in both groups. Mortality rate and MACE rates at 4-year follow-up were higher in Group B compared to Group A but have not reached statistical significance in univariable or multivariable analysis. Implantation of a self-apposing stent has been an independent predictor for target lesion revascularization rate (TLR) in multivariable analysis (HR 0.06, CI − 1.11–11.7, =0.03).</p>
</sec>
<sec><h3>Conclusions</h3>
<p>In our study, TLR rate was significantly higher in patients with left main lesion treated by PCI with self-apposing stents.</p>
</sec>
</abstract>

Background
Left main percutaneous coronary intervention (PCI) has been established as an effective and safe treatment option for left main coronary artery disease. There are data suggesting that different stent platforms can impact the outcomes after left main PCI. The aim of current study was to compare the four-year outcomes of patients with left main stenosis treated by PCI with a balloon-expandable stent or a self-apposing stent.

Methods and Results
A total of 146 patients with left main stenosis treated by PCI were included, of which 84 (57.5%) had balloon-expandable stents (Group A) and 62 (42.5%) had self-apposing stents (Group B). Baseline SYNTAX scores were higher in Group A than in Group B. Proximal optimization technique was used more often in Group A (45.2% in Group B vs 81.4% in Group A, p<0.001). The same observations were made for kissing balloon postdilation (30.6% Group B vs 62.7% in Group A, p<0.001).
Procedural success with TIMI 3 flow was achieved in similar proportions in both groups. Mortality rate and MACE rates at 4-year follow-up were higher in Group B compared to Group A but have not reached statistical significance in univariable or multivariable analysis. Implantation of a self-apposing stent has been an independent predictor for target lesion revascularization rate (TLR) in multivariable analysis (HR 0.06, CI − 1.11–11.7, =0.03).

Conclusions
In our study, TLR rate was significantly higher in patients with left main lesion treated by PCI with self-apposing stents.

Four-Year Outcomes of Unprotected Left Main Lesion PCI with Self-Apposing Stents versus Balloon-Expandable Stents

Carol Davila” University of Medicine and Pharmacy

Romanian Journal of Cardiology

This work is licensed under the Creative Commons Attribution 4.0 International License.

Background
Left main percutaneous coronary intervention (PCI) has been established as an effective and safe treatment option for left main coronary artery...

Four-Year Outcomes of Unprotected Left Main Lesion PCI with Self-Apposing Stents versus Balloon-Expandable Stents

Article Category: Original Article

Publié en ligne: 22 avr. 2022

Pages: 2 - 9

DOI: https://doi.org/10.2478/rjc-2022-0004

Mots clés
percutaneous coronary intervention, left main coronary artery disease, balloon-expandable stent, self-apposing stent

© 2022 Lucian Predescu et al., published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.

Four-Year Outcomes of Unprotected Left Main Lesion PCI with Self-Apposing Stents versus Balloon-Expandable Stents

Article Category: Original Article

Publié en ligne: 22 avr. 2022

Pages: 2 - 9

DOI: https://doi.org/10.2478/rjc-2022-0004

Mots cléspercutaneous coronary intervention, left main coronary artery disease, balloon-expandable stent, self-apposing stent

© 2022 Lucian Predescu et al., published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.

Mots clés
percutaneous coronary intervention, left main coronary artery disease, balloon-expandable stent, self-apposing stent