<abstract xmlns="http://www.w3.org/1999/xhtml">

<p>Chronic obstructive pulmonary disease (COPD) and obstructive sleep apnoea (OSA) syndrome (OSAS) are both common conditions. Their comorbid association – overlap syndrome (OVS) – can result in clinically important nocturnal oxygen desaturation. We sought to compare demographic and anthropometric characteristics, associated comorbidities and oxygen saturation in patients with OVS versus OSA alone.</p>
<sec><h3>Methods</h3>
<p>We included consecutive patients diagnosed with OSA in our sleep laboratory. Overnight sleep studies were performed, and data regarding demographic and anthropometric characteristics, prevalence of comorbidities and somnographic parameters were compared for patients with OVS versus OSA alone. A P value of &lt;0.05 was considered significant.</p>
</sec>
<sec><h3>Results</h3>
<p>A total of 2173 OSA patients were assessed, of whom 381 (17.5%) had OVS. Significant differences were found between the OVS and OSA groups regarding all evaluated demographic and anthropometric characteristics, prevalence of comorbidities and somnographic parameters.</p>
</sec>
<sec><h3>Conclusions</h3>
<p>OVS patients were older, were predominantly male, had a higher prevalence of common cardiovascular and metabolic comorbidities, and had worse apnoea–hypopnoea index (AHI) and oxygen saturation parameters.</p>
</sec>
</abstract>

Chronic obstructive pulmonary disease (COPD) and obstructive sleep apnoea (OSA) syndrome (OSAS) are both common conditions. Their comorbid association – overlap syndrome (OVS) – can result in clinically important nocturnal oxygen desaturation. We sought to compare demographic and anthropometric characteristics, associated comorbidities and oxygen saturation in patients with OVS versus OSA alone.
Methods
We included consecutive patients diagnosed with OSA in our sleep laboratory. Overnight sleep studies were performed, and data regarding demographic and anthropometric characteristics, prevalence of comorbidities and somnographic parameters were compared for patients with OVS versus OSA alone. A P value of <0.05 was considered significant.

Results
A total of 2173 OSA patients were assessed, of whom 381 (17.5%) had OVS. Significant differences were found between the OVS and OSA groups regarding all evaluated demographic and anthropometric characteristics, prevalence of comorbidities and somnographic parameters.

Conclusions
OVS patients were older, were predominantly male, had a higher prevalence of common cardiovascular and metabolic comorbidities, and had worse apnoea–hypopnoea index (AHI) and oxygen saturation parameters.

Severity of oxygen desaturation in OSA–COPD overlap syndrome compared to OSA alone: an observational cohort study

Department of Pulmonology, Center for Research and Innovation in Precision Medicine of Respiratory Diseases

“Victor Babes” University of Medicine and Pharmacy

Pneumologia

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Chronic obstructive pulmonary disease (COPD) and obstructive sleep apnoea (OSA) syndrome (OSAS) are both common conditions. Their comorbid association –...

Severity of oxygen desaturation in OSA–COPD overlap syndrome compared to OSA alone: an observational cohort study

Publié en ligne: 28 juin 2023

Pages: 22 - 27

DOI: https://doi.org/10.2478/pneum-2023-0017

Mots clés
overlap syndrome, sleep apnoea, oxygen desaturation, comorbidities

© 2022 Bianca Stepan et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Severity of oxygen desaturation in OSA–COPD overlap syndrome compared to OSA alone: an observational cohort study

Publié en ligne: 28 juin 2023

Pages: 22 - 27

DOI: https://doi.org/10.2478/pneum-2023-0017

Mots clésoverlap syndrome, sleep apnoea, oxygen desaturation, comorbidities

© 2022 Bianca Stepan et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Mots clés
overlap syndrome, sleep apnoea, oxygen desaturation, comorbidities