VO2 peak or VO2 max | Bechard et al. 1987 (n = 50) (30) | <10 ml/kg/min | 29% mortality and 43% morbidity (10.7% morbidity if 10 < VO2 max < 20 ml/kg/min; no mortality/morbidity if VO2 >20 ml/kg/min) |
Brunelli et al. 2009 (n = 204) (31) | <12 ml/kg/min | 13% mortality and 33% morbidity (no mortality, 3.5% morbidity if VO2 >20 ml/kg/min) |
Smith et al. 1984 (n = 22) (32) | <15 ml/kg/min | 100% morbidity |
Byram et al. 2007 (n = 55) (33) | | 39% morbidity (no morbidity if VO2 ≥ 15 ml/kg/min) |
Bolliger et al. 1995 (n = 80) (35) | <60% | 85.5% probability of complications after resection involving more than one lobe |
| <43% | 90% probability of serious complications |
Larsen et al. 1997 (n = 97) (36) | <50% | 60% sensitivity of mortality risk |
AT | Guazzi et al. 2016 (39) | <11 ml/kg/min | High risk of complications (proposed prognostic marker) |
VE/VCO2 slope | Torchio et al. 2010 (n = 145) (40) | ≥34 | 5.5% of patients predicted not to survive after surgery (98% of patients predicted to survive if VE/VCO2 <34) |
The only independent mortality predictor |
Brunelli et al. 2012 (n = 225) (41) | >35 | High risk of respiratory complications (22% vs. 7.6%) and mortality (7.2% vs. 0.6%); comparison with patients with VE/VO2 ≤35 |
Miyazaki et al. 2018 (n = 974) (44) | >40 | 90-day mortality: 16% vs. 5% |
2-year mortality: no difference (comparison with patients with VE/VCO2 ≤40) |