<abstract xmlns="http://www.w3.org/1999/xhtml"><p>SCMNPs@Uridine/Zn is utilized as an environmental-friendly and efficient heterogeneous nanocatalyst for two one-pot four-component condensation reactions, containing hydrazine hydrate, arylaldehyde, ethyl acetoacetate, and barbituric acid to yield tricyclic fused pyrazolopyranopyrimidine derivatives (5a-q), and hydrazine hydrate, arylaldehyde, malononitrile, and dimethyl acetylenedicarboxylate/diethyl acetylenedicarboxylate to yield 3-methyl carboxylate substituted pyrano[2,3-<italic>c</italic>]pyrazole derivatives (8a-y) under solvent-free conditions with high to excellent yields. The main advantages of this process are easy work-up, short reaction times, no chromatographic purifications, and recyclability of the catalyst for a minimum of six runs without any significant decrease in yields of the products. Also, the prepared catalyst SCMNPs@Uridine/Zn was synthesized and fully characterized by various techniques including Fourier transform infrared spectroscopy (FT-IR), energy dispersive X-ray (EDX), thermogravimetric analysis (TGA), X-ray diffraction (XRD), vibrating sample magnetometer (VSM) and Raman spectroscopy.</p></abstract>

SCMNPs@Uridine/Zn is utilized as an environmental-friendly and efficient heterogeneous nanocatalyst for two one-pot four-component condensation reactions, containing hydrazine hydrate, arylaldehyde, ethyl acetoacetate, and barbituric acid to yield tricyclic fused pyrazolopyranopyrimidine derivatives (5a-q), and hydrazine hydrate, arylaldehyde, malononitrile, and dimethyl acetylenedicarboxylate/diethyl acetylenedicarboxylate to yield 3-methyl carboxylate substituted pyrano[2,3-c]pyrazole derivatives (8a-y) under solvent-free conditions with high to excellent yields. The main advantages of this process are easy work-up, short reaction times, no chromatographic purifications, and recyclability of the catalyst for a minimum of six runs without any significant decrease in yields of the products. Also, the prepared catalyst SCMNPs@Uridine/Zn was synthesized and fully characterized by various techniques including Fourier transform infrared spectroscopy (FT-IR), energy dispersive X-ray (EDX), thermogravimetric analysis (TGA), X-ray diffraction (XRD), vibrating sample magnetometer (VSM) and Raman spectroscopy.

SCMNPs@Uridine/Zn: An efficient and reusable heterogeneous nanocatalyst for the rapid one-pot synthesis of tricyclic fused pyrazolopyranopyrimidine and 3-methyl carboxylate substituted pyrano[2,3-<italic>c</italic>]pyrazole derivatives under solvent-free conditions

Polish Journal of Chemical Technology

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

SCMNPs@Uridine/Zn: An efficient and reusable heterogeneous nanocatalyst for the rapid one-pot synthesis of tricyclic fused pyrazolopyranopyrimidine and 3-methyl carboxylate substituted pyrano[2,3-]pyrazole derivatives under solvent-free conditions

SCMNPs@Uridine/Zn is utilized as an environmental-friendly and efficient heterogeneous nanocatalyst for two one-pot four-component condensation reactions,...

SCMNPs@Uridine/Zn: An efficient and reusable heterogeneous nanocatalyst for the rapid one-pot synthesis of tricyclic fused pyrazolopyranopyrimidine and 3-methyl carboxylate substituted pyrano[2,3-c]pyrazole derivatives under solvent-free conditions

Publié en ligne: 13 mai 2020

Pages: 20 - 33

DOI: https://doi.org/10.2478/pjct-2020-0013

Mots clés
nanocatalyst, synthesis of tricyclic, carboxylate, efficient heterogeneous

© 2020 Jia Wei et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

SCMNPs@Uridine/Zn: An efficient and reusable heterogeneous nanocatalyst for the rapid one-pot synthesis of tricyclic fused pyrazolopyranopyrimidine and 3-methyl carboxylate substituted pyrano[2,3-c]pyrazole derivatives under solvent-free conditions

Publié en ligne: 13 mai 2020

Pages: 20 - 33

DOI: https://doi.org/10.2478/pjct-2020-0013

Mots clésnanocatalyst, synthesis of tricyclic, carboxylate, efficient heterogeneous

© 2020 Jia Wei et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Mots clés
nanocatalyst, synthesis of tricyclic, carboxylate, efficient heterogeneous