<abstract xmlns="http://www.w3.org/1999/xhtml"><p>Herein, a simple and effective method for the preparation of thiourea using a nucleophilic substitution reaction is reported. Urea and Lawesson’s reagent were used as the raw materials to prepare thiourea via a one-step method involving the sulfuration reaction, and the reaction mechanism was analyzed. The effect of the reaction time, reaction temperature, and mass ratio of the raw materials on the yield of thiourea were investigated.The most beneficial conditions used for the reaction were determined to be: Reaction time = 3.5 h, reaction temperature = 75°C, and mass ratio of urea to Lawesson’s reagent = 2:1. Under these optimal conditions, the average yield of thiourea over five replicate experiments was 62.37%. Characterization using Fourier transform infrared (FTIR) spectroscopy, X-ray diffraction (XRD) and thermogravimetric analysis (TGA) showed that the as-synthesized substance was thiourea. Our synthetic method has the advantages of high yield, mild reaction conditions and simplicity.</p></abstract>

Herein, a simple and effective method for the preparation of thiourea using a nucleophilic substitution reaction is reported. Urea and Lawesson’s reagent were used as the raw materials to prepare thiourea via a one-step method involving the sulfuration reaction, and the reaction mechanism was analyzed. The effect of the reaction time, reaction temperature, and mass ratio of the raw materials on the yield of thiourea were investigated.The most beneficial conditions used for the reaction were determined to be: Reaction time = 3.5 h, reaction temperature = 75°C, and mass ratio of urea to Lawesson’s reagent = 2:1. Under these optimal conditions, the average yield of thiourea over five replicate experiments was 62.37%. Characterization using Fourier transform infrared (FTIR) spectroscopy, X-ray diffraction (XRD) and thermogravimetric analysis (TGA) showed that the as-synthesized substance was thiourea. Our synthetic method has the advantages of high yield, mild reaction conditions and simplicity.

Synthesis and characterization of thiourea

Polish Journal of Chemical Technology

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

{"article-title":"Synthesis and characterization of thiourea"}

Herein, a simple and effective method for the preparation of thiourea using a nucleophilic substitution reaction is reported. Urea and Lawesson’s reagent were...

Synthesis and characterization of thiourea

Publié en ligne: 26 sept. 2019

Pages: 35 - 39

DOI: https://doi.org/10.2478/pjct-2019-0027

Mots clés
Urea, Lawesson’s reagent, thiourea, vulcanization reaction, Nucleophilic substitution

© 2019 Chuanbo Dai et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Synthesis and characterization of thiourea

Publié en ligne: 26 sept. 2019

Pages: 35 - 39

DOI: https://doi.org/10.2478/pjct-2019-0027

Mots clésUrea, Lawesson’s reagent, thiourea, vulcanization reaction, Nucleophilic substitution

© 2019 Chuanbo Dai et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Mots clés
Urea, Lawesson’s reagent, thiourea, vulcanization reaction, Nucleophilic substitution