CMV seropositivity does not increase the risk of death among elderly nursing home residents

1. Lubeck PR, Doerr HW, Rabenau HF. Epidemiology of human cytomegalovirus (HCMV) in an urban region of Germany: what has changed? Med Microbiol Immunol. 2010;199:53-60.Search in Google Scholar

2. Matheï C, Adriaensen W, Vaes B, et al. No relation between CMV infection and mortality in the oldest old: results from the Belfrail study. Age Ageing. 2015;44(1):130-135. doi: 10.1093/ageing/afu094.10.1093/ageing/afu09425026957Search in Google Scholar

3. Michael J. Cannon, D. Schmid S, et al. Review of cytomegalovirus seroprevalence and demographic characteristics associated with infection. Reviews in Medical Virology. 2010;20 (4):202-213.10.1002/rmv.65520564615Search in Google Scholar

4. Feinstein L, Douglas CE, Stebbins RC, et al. Does cytomegalovirus infection contribute to socioeconomic disparities in all-cause mortality? Mech Ageing Dev. 2016;158:53-61. doi:10.1016/j.mad.2016.06.00110.1016/j.mad.2016.06.001501820627268074Search in Google Scholar

5. Stowe RP, Kozlova EV, Yetman DL, et al. Chronic herpesvirus reactivation occurs in aging. Exp Gerontol. 2007;42:563-570.10.1016/j.exger.2007.01.005199244117337145Search in Google Scholar

6. Aiello AE, Haan MN, Blythe L, et al. The influence of latent viral infection on rate of cognitive decline over 4 years. J Am Geriatr Soc. 2006;54:1046-1054. doi: 10.1111/j.1532-5415.2006.00796.x.10.1111/j.1532-5415.2006.00796.x16866674Search in Google Scholar

7. Schmaltz HN, Fried LP, Xue QL, et al. Chronic cytomegalovirus infection and inflammation are associated with prevalent frailty in community-dwelling older women. J Am Geriatr Soc. 2005;53(5):747-754.10.1111/j.1532-5415.2005.53250.x15877548Search in Google Scholar

8. Fried LP, Tangen CM, Walston J, et al. Frailty in older adults: evidence for a phenotype. J Gerontol A Biol Sci Med Sci. 2001;56(3):M146-M156.10.1093/gerona/56.3.M14611253156Search in Google Scholar

9. Simanek AM, Dowd JB, Aiello AE. Persistent pathogens linking socioeconomic position and cardiovascular disease in the US. Int J Epidemiol. 2009;38(3):775–787.10.1093/ije/dyn273268939419109247Search in Google Scholar

10. Samanta M, Harkins L, Klemm K, et al. High prevalence of human cytomegalovirus in prostatic intraepithelial neoplasia and prostatic carcinoma. J Urol. 2003;170(3):998–1002.10.1097/01.ju.0000080263.46164.9712913758Search in Google Scholar

11. Savva GM, Pachnio A, Kaul B, et al. Cytomegalovirus infection is associated with increased mortality in the older population. Aging Cell. 2013;12(3):381-7.10.1111/acel.1205923442093Search in Google Scholar

12. Khan N, Hislop A, Gudgeon N, et al. Herpesvirus-specific CD8 T cell immunity in old age: cytomegalovirus impairs the response to a coresident EBV infection. J Immunol. 2004;173:7481-7489.10.4049/jimmunol.173.12.748115585874Search in Google Scholar

13. Vescovini R, Telera A, Fagnoni FF, et al. Different contribution of EBV and CMV infections in very long-term carriers to age-related alterations of CD8+ T cells. Exp Gerontol. 2004;39:1233-1243.10.1016/j.exger.2004.04.00415288697Search in Google Scholar

14. Zaia JA, Gallez-Hawkins GM, Tegtmeier BR, et al. Late cytomegalovirus disease in marrow transplantation is predicted by virus load in plasma, J Infect Dis. 1997; 176: 782-785.Search in Google Scholar

15. Wang GC, Kao WHL, Murakami P, et al. Cytomegalovirus Infection and the Risk of Mortality and Frailty in Older Women: A Prospective Observational Cohort Study. American Journal of Epidemiology. 2010;171(10):1144-1152.10.1093/aje/kwq062287747020400465Search in Google Scholar

16. Lopo S, Vinagre E, Palminha P, et al. Seroprevalence to cytomegalovirus in the Portuguese population, 2002–2003. Euro Surveill. 2011;16(25). pii: 19896.10.2807/ese.16.25.19896-enSearch in Google Scholar

17. Olsson J, Kok E, Adolfsson R, et al. Herpes virus seroepidemiology in the adult Swedish population. Immun Ageing. 2017;14:10 10.1186/s12979-017-0093-410.1186/s12979-017-0093-4542439328491117Search in Google Scholar

18. Antona D, Lepoutre A, Fonteneau L, et al. Seroprevalence of cytomegalovirus infection in France in 2010. Epidemiol Infect. 2017;45(7):1471-1478. doi: 10.1017/S095026881700010310.1017/S095026881700010328166842Search in Google Scholar

19. Pawelec G, McElhaney JE, Aiello AE, et al. The impact of CMV infection on survival in older humans. Curr Opin Immunol. 2012;24:507-511.10.1016/j.coi.2012.04.00222541724Search in Google Scholar

20. Staras SA, Dollard SC, Radford KW, et al. Seroprevalence of cytomegalovirus infection in the United States, 1988-1994. Clin Infect Dis. 2006;43:1143–1151.10.1086/50817317029132Search in Google Scholar

21. Krmpotić A, Podlech J, Reddehase MJ, et al. Role of antibodies in confining cytomegalovirus after reactivation from latency: three decades’ résumé. Med Microbiol Immunol 2019;208:415-429. https://doi.org/10.1007/s00430-019-00600-110.1007/s00430-019-00600-1670560830923898Search in Google Scholar