First report of Mycobacterium avium subsp. hominissuis in a black howler monkey (Alouatta caraya): a study with mycobacterial interspersed repetitive unit–variable number of tandem repeats genetic profiling

Over the past three decades, emerging epidemiological evidence has shown the increasing incidence and prevalence of nontuberculous mycobacteria (NTM). As a result, clinical awareness of the impact these organisms have on both human and animal health has grown.

Material and Methods

Two captive black howler monkeys (Alouatta caraya) were experiencing recurrent diarrhoea. Their faecal samples were processed by suspension, decontamination and culture to propagate Mycobacterium. Immunochromatography and molecular studies were undertaken to detect parasites. The antimicrobial susceptibility of bacterial isolates was tested using broth microdilution. Additionally, mycobacterial interspersed repetitive unit-variable number of tandem repeats (MIRU-VNTR) typing was performed to assess the Mycobacterium pattern.

Results

Mycobacterium avium subsp. hominissuis was identified and noted to have a novel MIRU-VNTR pattern (22221229). No parasites were detected by immunochromatography, but Giardia intestinalis was identified by PCR. This marks the first documented case of co-infection with Mycobacterium avium subsp. hominissuis and Giardia intestinalis in a black howler monkey.

Conclusion

Collecting clinical isolates from infected animals is vital for comparing them with other isolates, including those from the environment, and for re-evaluating their potential as pathogens. Our study is significant within the context of veterinary disease control and the One Health approach.

Langue:: Anglais

Périodicité:: 4 fois par an
Sujets de la revue:: Sciences de la vie, Biologie moléculaire, Microbiologie et virologie, Sciences de la vie, autres, Médecine, Médecine vétérinaire

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First report of Mycobacterium avium subsp. hominissuis in a black howler monkey (Alouatta caraya): a study with mycobacterial interspersed repetitive unit–variable number of tandem repeats genetic profiling

Anna Didkowska

Marta Majchrzak

Michał Załuski

Sylwia Brzezińska

Dawid Jańczak

Magdalena Nowak

Wiktoria Tchórz

Ewa Augustynowicz-Kopeć

Katarzyna Matusik

Paweł Parniewski

Publié en ligne: 06 mai 2025

Pages: 191 - 197

Reçu: 20 déc. 2024

Accepté: 28 avr. 2025

DOI: https://doi.org/10.2478/jvetres-2025-0027

Mots clésatypical mycobacteria, MAH, nonhuman primates, zoonosis

© 2025 Anna Didkowska et al., published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.

Introduction

Material and Methods

Results

Conclusion

Mots clés
atypical mycobacteria, MAH, nonhuman primates, zoonosis