The effect of consumption of cranberry (Vaccinium macrocarpon) on Escherichia coli adherence to feline uroepithelial cells in a blind randomised cross-over trial in cats

1. Al-Badr A., Al-Shaikh G.: Recurrent Urinary Tract Infections Management in Women: A review. Sultan Qaboos Univ Med J 2013, 13, 359–367, doi: 10.12816/0003256. Al-Badr A. Al-Shaikh G. : Recurrent Urinary Tract Infections Management in Women: A review . Sultan Qaboos Univ Med J 2013 , 13 , 359 – 367 , doi: 10.12816/0003256 . Open DOISearch in Google Scholar

2. Aurich S., Prenger-Berninghoff E., Ewers C.: Prevalence and Antimicrobial Resistance of Bacterial Uropathogens Isolated from Dogs and Cats. Antibiotics (Basel) 2022, 11, 1730, doi: 10.3390/antibiotics11121730. Aurich S. Prenger-Berninghoff E. Ewers C. : Prevalence and Antimicrobial Resistance of Bacterial Uropathogens Isolated from Dogs and Cats . Antibiotics (Basel) 2022 , 11 , 1730 , doi: 10.3390/antibiotics11121730 . Open DOISearch in Google Scholar

3. Buffington C.A., Westropp J.L., Chew D.J., Bolus R.R.: Risk factors associated with clinical signs of lower urinary tract disease in indoor-housed cats. J Am Vet Med Assoc 2006, 228, 722–725, doi: 10.2460/javma.228.5.722. Buffington C.A. Westropp J.L. Chew D.J. Bolus R.R. : Risk factors associated with clinical signs of lower urinary tract disease in indoor-housed cats . J Am Vet Med Assoc 2006 , 228 , 722 – 725 , doi: 10.2460/javma.228.5.722 . Open DOISearch in Google Scholar

4. Carvajal-Campos A., Jeusette I., Mayot G., Torre C., André A., Di Martino P.: Adherence of uropathogenic Escherichia coli in dog urine after consumption of food supplemented with cranberry (Vaccinium Macrocarpon). J Vet Res 2023, 67, 49–54, doi: 10.2478/jvetres-2023-0004. Carvajal-Campos A. Jeusette I. Mayot G. Torre C. André A. Di Martino P. : Adherence of uropathogenic Escherichia coli in dog urine after consumption of food supplemented with cranberry (Vaccinium Macrocarpon) . J Vet Res 2023 , 67 , 49 – 54 , doi: 10.2478/jvetres-2023-0004 . Open DOISearch in Google Scholar

5. Chou H.I., Chen K.S., Wang H.C., Lee W.M.: Effects of cranberry extract on prevention of urinary tract infection in dogs and on adhesion of Escherichia coli to Madin-Darby canine kidney cells. Am J Vet Res 2016, 77, 421–427, doi: 10.2460/ajvr.77.4.421. Chou H.I. Chen K.S. Wang H.C. Lee W.M. : Effects of cranberry extract on prevention of urinary tract infection in dogs and on adhesion of Escherichia coli to Madin-Darby canine kidney cells . Am J Vet Res 2016 , 77 , 421 – 427 , doi: 10.2460/ajvr.77.4.421 . Open DOISearch in Google Scholar

6. Colombino E., Cavana P., Martello E., Devalle V., Miniscalco B., Ravera N., Zanatta R., Capucchio M.T., Biasibetti E.: A new diet supplement formulation containing cranberry extract for the treatment of feline idiopathic cystitis. Nat Prod Res 2021, 36, 2884–2887, doi: 10.1080/14786419.2021.1925273. Colombino E. Cavana P. Martello E. Devalle V. Miniscalco B. Ravera N. Zanatta R. Capucchio M.T. Biasibetti E. : A new diet supplement formulation containing cranberry extract for the treatment of feline idiopathic cystitis . Nat Prod Res 2021 , 36 , 2884 – 2887 , doi: 10.1080/14786419.2021.1925273 . Open DOISearch in Google Scholar

7. Crozier A., Del Rio D., Clifford M.N.: Bioavailability of dietary flavonoids and phenolic compounds. Mol Aspects Med 2010, 31, 446–467, doi: 10.1016/j.mam.2010.09.007. Crozier A. Del Rio D. Clifford M.N. : Bioavailability of dietary flavonoids and phenolic compounds . Mol Aspects Med 2010 , 31 , 446 – 467 , doi: 10.1016/j.mam.2010.09.007 . Open DOISearch in Google Scholar

8. Di Lorenzo C., Colombo F., Biella S., Stockley C., Restani P.: Polyphenols and Human Health: The Role of Bioavailability. Nutrients 2021, 13, 273, doi: 10.3390/nu13010273. Di Lorenzo C. Colombo F. Biella S. Stockley C. Restani P. : Polyphenols and Human Health: The Role of Bioavailability . Nutrients 2021 , 13 , 273 , doi: 10.3390/nu13010273 . Open DOISearch in Google Scholar

9. Di Martino P., Agniel R., David K., Templer C., Gaillard J.L., Denys P., Botto H.: Reduction of Escherichia coli adherence to uroepithelial bladder cells after consumption of cranberry juice: a double-blind randomized placebo-controlled cross-over trial. World J Urol 2006, 24, 21–27, doi: 10.1007/s00345-005-0045-z. Di Martino P. Agniel R. David K. Templer C. Gaillard J.L. Denys P. Botto H. : Reduction of Escherichia coli adherence to uroepithelial bladder cells after consumption of cranberry juice: a double-blind randomized placebo-controlled cross-over trial . World J Urol 2006 , 24 , 21 – 27 , doi: 10.1007/s00345-005-0045-z . Open DOISearch in Google Scholar

10. Dorsch R., Teichmann-Knorrn S., Sjetne Lund H.: Urinary tract infection and subclinical bacteriuria in cats: A clinical update. J Feline Med Surg 2019, 21, 1023–1038, doi: 10.1177/1098612X19880435. Dorsch R. Teichmann-Knorrn S. Sjetne Lund H. : Urinary tract infection and subclinical bacteriuria in cats: A clinical update . J Feline Med Surg 2019 , 21 , 1023 – 1038 , doi: 10.1177/1098612X19880435 . Open DOISearch in Google Scholar

11. Freitag T., Squires R.A., Schmid J., Elliott J.: Feline uropathogenic Escherichia coli from Great Britain and New Zealand have dissimilar virulence factor genotypes. Vet Microbiol 2005, 106, 79–86, doi: 10.1016/j.vetmic.2004.11.014. Freitag T. Squires R.A. Schmid J. Elliott J. : Feline uropathogenic Escherichia coli from Great Britain and New Zealand have dissimilar virulence factor genotypes . Vet Microbiol 2005 , 106 , 79 – 86 , doi: 10.1016/j.vetmic.2004.11.014 . Open DOISearch in Google Scholar

12. Freitag T., Squires R.A., Schmid J., Elliott J., Rycroft A.N.: Antibiotic sensitivity profiles do not reliably distinguish relapsing or persisting infections from reinfections in cats with chronic renal failure and multiple diagnoses of Escherichia coli urinary tract infection. J Vet Intern Med 2006, 20, 245–249, doi: 10.1892/0891-6640(2006)20[245:aspdnr]2.0.co;2. Freitag T. Squires R.A. Schmid J. Elliott J. Rycroft A.N. : Antibiotic sensitivity profiles do not reliably distinguish relapsing or persisting infections from reinfections in cats with chronic renal failure and multiple diagnoses of Escherichia coli urinary tract infection . J Vet Intern Med 2006 , 20 , 245 – 249 , doi: 10.1892/0891-6640(2006)20[245:aspdnr]2.0.co;2 . Open DOISearch in Google Scholar

13. Hernando E., Vila A., D’Ippolito P., Rico A.J., Rodon J., Roura X.: Prevalence and Characterization of Urinary Tract Infection in Owned Dogs and Cats From Spain. Topics in Companion An Med 2021, 43, 100512, doi: 10.1016/j.tcam.2021.100512. Hernando E. Vila A. D’Ippolito P. Rico A.J. Rodon J. Roura X. : Prevalence and Characterization of Urinary Tract Infection in Owned Dogs and Cats From Spain . Topics in Companion An Med 2021 , 43 , 100512 , doi: 10.1016/j.tcam.2021.100512 . Open DOISearch in Google Scholar

14. Howell A.B., Vorsa N., Der Marderosian A., Foo L.Y.: Inhibition of adherence of P-fimbriated Escherichia coli to uroepithelial-cell surfaces by proanthocyanidin extracts from cranberries. N Engl J Med 1998, 339, 1085–1086. Howell A.B. Vorsa N. Der Marderosian A. Foo L.Y. : Inhibition of adherence of P-fimbriated Escherichia coli to uroepithelial-cell surfaces by proanthocyanidin extracts from cranberries . N Engl J Med 1998 , 339 , 1085 – 1086 . Search in Google Scholar

15. Johnson J.R., Johnston B., Clabots C.R., Kuskowski M.A., Roberts E., DebRoy C.: Virulence genotypes and phylogenetic background of Escherichia coli serogroup O6 isolates from humans, dogs, and cats. J Clin Microbiol 2008, 46, 417–422, doi: 10.1128/JCM.00674-07. Johnson J.R. Johnston B. Clabots C.R. Kuskowski M.A. Roberts E. DebRoy C. : Virulence genotypes and phylogenetic background of Escherichia coli serogroup O6 isolates from humans, dogs, and cats . J Clin Microbiol 2008 , 46 , 417 – 422 , doi: 10.1128/JCM.00674-07 . Open DOISearch in Google Scholar

16. Litster A., Moss S.M., Honnery M., Rees B., Trott D.J.: Prevalence of bacterial species in cats with clinical signs of lower urinary tract disease: recognition of Staphylococcus felis as a possible feline urinary tract pathogen. Vet Microbiol 2007, 121, 182–188, doi: 10.1016/j.vetmic.2006.11.025. Litster A. Moss S.M. Honnery M. Rees B. Trott D.J. : Prevalence of bacterial species in cats with clinical signs of lower urinary tract disease: recognition of Staphylococcus felis as a possible feline urinary tract pathogen . Vet Microbiol 2007 , 121 , 182 – 188 , doi: 10.1016/j.vetmic.2006.11.025 . Open DOISearch in Google Scholar

17. Litster A., Moss S., Platell J., Trott D.J.: Occult bacterial lower urinary tract infections in cats-urinalysis and culture findings. Vet Microbiol 2009, 136, 130–134, doi: 10.1016/j.vetmic.2008.10.019. Litster A. Moss S. Platell J. Trott D.J. : Occult bacterial lower urinary tract infections in cats-urinalysis and culture findings . Vet Microbiol 2009 , 136 , 130 – 134 , doi: 10.1016/j.vetmic.2008.10.019 . Open DOISearch in Google Scholar

18. Liu Y., Black M. A., Caron L., Camesano T.A.: Role of cranberry juice on molecular-scale surface characteristics and adhesion behavior of Escherichia coli. Biotechnol Bioeng 2006, 93, 297–305. Liu Y. Black M. A. Caron L. Camesano T.A. : Role of cranberry juice on molecular-scale surface characteristics and adhesion behavior of Escherichia coli . Biotechnol Bioeng 2006 , 93 , 297 – 305 . Search in Google Scholar

19. Mayer-Roenne B., Goldstein R.E., Erb H.N.: Urinary tract infections in cats with hyperthyroidism, diabetes mellitus and chronic kidney disease. J Feline Med Surg 2007, 9, 124–132, doi: 10.1016/j.jfms.2006.09.004. Mayer-Roenne B. Goldstein R.E. Erb H.N. : Urinary tract infections in cats with hyperthyroidism, diabetes mellitus and chronic kidney disease . J Feline Med Surg 2007 , 9 , 124 – 132 , doi: 10.1016/j.jfms.2006.09.004 . Open DOISearch in Google Scholar

20. Mayot G., Secher C., Di Martino P.: Inhibition of adhesion of uropathogenic Escherichia coli to canine and feline uroepithelial cells by an extract from cranberry. J Microbiol Biotechnol Food Sci 2018, 7, 404–406, doi: 10.15414/jmbfs.2018.7.4.404-406. Mayot G. Secher C. Di Martino P. : Inhibition of adhesion of uropathogenic Escherichia coli to canine and feline uroepithelial cells by an extract from cranberry . J Microbiol Biotechnol Food Sci 2018 , 7 , 404 – 406 , doi: 10.15414/jmbfs.2018.7.4.404-406 . Open DOISearch in Google Scholar

21. Moon D.C., Choi J.H., Boby N., Kim S.J., Song H.J., Park H.S., Gil M.C., Yoon S.S., Lim S.K.: Prevalence of Bacterial Species in Skin, Urine, Diarrheal Stool, and Respiratory Samples in Cats. Pathogens 2022, 11, 324, doi: 10.3390/pathogens11030324. Moon D.C. Choi J.H. Boby N. Kim S.J. Song H.J. Park H.S. Gil M.C. Yoon S.S. Lim S.K. : Prevalence of Bacterial Species in Skin, Urine, Diarrheal Stool, and Respiratory Samples in Cats . Pathogens 2022 , 11 , 324 , doi: 10.3390/pathogens11030324 . Open DOISearch in Google Scholar

22. Nieradka R.: The use of cranberry extract and glucosamine in the treatment of lower urinary tract infections in small animals. PART II. Urinary tract infections in cats. Vet Life 2019, 4, 41–44, https://vetexpert.eu/wp-content/uploads/2022/05/DVM times_EN_ 4_20190913_preview.pdf. Nieradka R. : The use of cranberry extract and glucosamine in the treatment of lower urinary tract infections in small animals . PART II. Urinary tract infections in cats. Vet Life 2019 , 4 , 41 – 44 , https://vetexpert.eu/wp-content/uploads/2022/05/DVM times_EN_4_20190913_preview.pdf . Search in Google Scholar

23. Occhipinti A., Germano A., Maffei M.E.: Prevention of Urinary Tract Infection with Oximacro®, A Cranberry Extract with a High Content of A-Type Proanthocyanidins: A Pre-Clinical DoubleBlind Controlled Study. Urol J 2016, 13, 2640–2649, doi: 10.22037/uj.v13i2.3190. Occhipinti A. Germano A. Maffei M.E. : Prevention of Urinary Tract Infection with Oximacro®, A Cranberry Extract with a High Content of A-Type Proanthocyanidins: A Pre-Clinical DoubleBlind Controlled Study . Urol J 2016 , 13 , 2640 – 2649 , doi: 10.22037/uj.v13i2.3190 . Open DOISearch in Google Scholar

24. Osugui L., de Castro A.F., Iovine R., Irino K., Carvalho V.M.: Virulence genotypes, antibiotic resistance and the phylogenetic background of extraintestinal pathogenic Escherichia coli isolated from urinary tract infections of dogs and cats in Brazil. Vet Microbiol 2014, 171, 242–247, doi: 10.1016/j.vetmic.2014.03.027. Osugui L. de Castro A.F. Iovine R. Irino K. Carvalho V.M. : Virulence genotypes, antibiotic resistance and the phylogenetic background of extraintestinal pathogenic Escherichia coli isolated from urinary tract infections of dogs and cats in Brazil . Vet Microbiol 2014 , 171 , 242 – 247 , doi: 10.1016/j.vetmic.2014.03.027 . Open DOISearch in Google Scholar

25. Poirel L., Madec J.Y., Lupo A., Schink A.K., Kieffer N., Nordmann P., Schwarz S.: Antimicrobial Resistance in Escherichia coli. Microbiol Spectr 2018, 6, doi: 10.1128/microbiolspec.ARBA-0026-2017. Poirel L. Madec J.Y. Lupo A. Schink A.K. Kieffer N. Nordmann P. Schwarz S. : Antimicrobial Resistance in Escherichia coli . Microbiol Spectr 2018 , 6 , doi: 10.1128/microbiolspec.ARBA-0026-2017 . Open DOISearch in Google Scholar

26. Raditic D.M.: Complementary and integrative therapies for lower urinary tract diseases. Vet Clin North Am Small Anim Pract 2015, 45, 857–878, doi: 10.1016/j.cvsm.2015.02.009. Raditic D.M. : Complementary and integrative therapies for lower urinary tract diseases . Vet Clin North Am Small Anim Pract 2015 , 45 , 857 – 878 , doi: 10.1016/j.cvsm.2015.02.009 . Open DOISearch in Google Scholar

27. Tempera G., Corsello S., Genovese C., Caruso F.E., Nicolosi D.: Inhibitory activity of cranberry extract on the bacterial adhesiveness in the urine of women: an ex vivo study. Int J Immunopathol Pharmacol 2010, 23, 611–618, doi: 10.1177/039463201002300223. Tempera G. Corsello S. Genovese C. Caruso F.E. Nicolosi D. : Inhibitory activity of cranberry extract on the bacterial adhesiveness in the urine of women: an ex vivo study . Int J Immunopathol Pharmacol 2010 , 23 , 611 – 618 , doi: 10.1177/039463201002300223 . Open DOISearch in Google Scholar

28. Terlizzi M.E., Gribaudo G., Maffei M.E.: UroPathogenic Escherichia coli (UPEC) infections: virulence factors, bladder responses, antibiotic, and non-antibiotic antimicrobial strategies. Front Microbiol 2017, 8, 1566, doi: 10.3389/fmicb.2017.01566. Terlizzi M.E. Gribaudo G. Maffei M.E. : UroPathogenic Escherichia coli (UPEC) infections: virulence factors, bladder responses, antibiotic, and non-antibiotic antimicrobial strategies . Front Microbiol 2017 , 8 , 1566 , doi: 10.3389/fmicb.2017.01566 . Open DOISearch in Google Scholar

29. Tramuta C., Nucera D., Robino P., Salvarani S., Nebbia P.: Virulence factors and genetic variability of uropathogenic Escherichia coli isolated from dogs and cats in Italy. J Vet Sci 2011, 12, 49–55, doi: 10.4142/jvs.2011.12.1.49. Tramuta C. Nucera D. Robino P. Salvarani S. Nebbia P. : Virulence factors and genetic variability of uropathogenic Escherichia coli isolated from dogs and cats in Italy . J Vet Sci 2011 , 12 , 49 – 55 , doi: 10.4142/jvs.2011.12.1.49 . Open DOISearch in Google Scholar

30. Vercelli C., Della Ricca M., Re M., Gambino G., Re G.: Antibiotic Stewardship for Canine and Feline Acute Urinary Tract Infection: An Observational Study in a Small Animal Hospital in Northwest Italy. Antibiotics (Basel) 2021, 10, 562, doi: 10.3390/antibiotics10050562. Vercelli C. Della Ricca M. Re M. Gambino G. Re G. : Antibiotic Stewardship for Canine and Feline Acute Urinary Tract Infection: An Observational Study in a Small Animal Hospital in Northwest Italy . Antibiotics (Basel) 2021 , 10 , 562 , doi: 10.3390/antibiotics10050562 . Open DOISearch in Google Scholar