<abstract xmlns="http://www.w3.org/1999/xhtml">

<sec id="j_jvetres-2023-0018_s_005">
<h3>Introduction</h3>
<p>Antimicrobial peptides, including cathelicidins, play a significant role in farm animals, influencing animal welfare, immunity, and thus the quality of animal products.</p>
</sec>
<sec id="j_jvetres-2023-0018_s_006">
<h3>Material and Methods</h3>
<p>The study used amplification-created restriction site and PCR-restriction fragment length polymorphism to analyse single nucleotide polymorphisms of the <italic>CATHL7</italic> gene encoding the BMAP-34 protein in cattle, at positions 2,383 <italic>G</italic> > <italic>C</italic> and 2,468 <italic>G</italic> > <italic>C</italic>. The material was collected from 279 Polish Black-and-White Holstein-Friesian dairy cows.</p>
</sec>
<sec id="j_jvetres-2023-0018_s_007">
<h3>Results</h3>
<p>There were statistically significant differences between milk performance parameters in cows with the <italic>CATHL7/Hha</italic>I and <italic>CATHL7/Hin</italic>fI genotypes. In the case of the <italic>CATHL7/Hha</italic>I polymorphism, the highest milk yield and protein and lactose content and the lowest somatic cell count in milk were observed for the <italic>CC</italic> genotype, while the fat content was the highest in milk from cows with the GG genotype. In the case of the <italic>CATHL7</italic>/<italic>Hin</italic>fI polymorphism, the highest protein and lactose content in milk was observed for the <italic>CC</italic> genotype.</p>
</sec>
<sec id="j_jvetres-2023-0018_s_008">
<h3>Conclusion</h3>
<p>The results were statistically significant, which suggests that the search for relationships can be continued, and that the results can be used to improve selection programmes supporting dairy farming.</p>
</sec>
</abstract>

Introduction
Antimicrobial peptides, including cathelicidins, play a significant role in farm animals, influencing animal welfare, immunity, and thus the quality of animal products.


Material and Methods
The study used amplification-created restriction site and PCR-restriction fragment length polymorphism to analyse single nucleotide polymorphisms of the CATHL7 gene encoding the BMAP-34 protein in cattle, at positions 2,383 G > C and 2,468 G > C. The material was collected from 279 Polish Black-and-White Holstein-Friesian dairy cows.


Results
There were statistically significant differences between milk performance parameters in cows with the CATHL7/HhaI and CATHL7/HinfI genotypes. In the case of the CATHL7/HhaI polymorphism, the highest milk yield and protein and lactose content and the lowest somatic cell count in milk were observed for the CC genotype, while the fat content was the highest in milk from cows with the GG genotype. In the case of the CATHL7/HinfI polymorphism, the highest protein and lactose content in milk was observed for the CC genotype.


Conclusion
The results were statistically significant, which suggests that the search for relationships can be continued, and that the results can be used to improve selection programmes supporting dairy farming.

Analysis of the effect of polymorphisms within the <italic>CATHL7</italic> gene on dairy performance parameters

Journal of Veterinary Research

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Analysis of the effect of polymorphisms within the  gene on dairy performance parameters

Introduction
Antimicrobial peptides, including cathelicidins, play a significant role in farm animals, influencing animal welfare, immunity, and thus the...

Analysis of the effect of polymorphisms within the CATHL7 gene on dairy performance parameters

Publié en ligne: 28 mars 2023

Pages: 123 - 129

Reçu: 05 janv. 2023

Accepté: 10 mars 2023

DOI: https://doi.org/10.2478/jvetres-2023-0018

Mots clés
ACRS, BMAP-34, cathelicidins, Holstein-Friesian cows, milk production traits

© 2023 S. Hiller et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Analysis of the effect of polymorphisms within the CATHL7 gene on dairy performance parameters

Publié en ligne: 28 mars 2023

Pages: 123 - 129

Reçu: 05 janv. 2023

Accepté: 10 mars 2023

DOI: https://doi.org/10.2478/jvetres-2023-0018

Mots clésACRS, BMAP-34, cathelicidins, Holstein-Friesian cows, milk production traits

© 2023 S. Hiller et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Mots clés
ACRS, BMAP-34, cathelicidins, Holstein-Friesian cows, milk production traits