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Bordt E.A., Polster B.M.: NADPH oxidase- and mitochondria-derived reactive oxygen species in proinflammatory microglial activation: a bipartisan affair? Free Radical Bio Med 2014, 76, 34–46, doi: 10.1016/j.freeradbiomed.2014.07.033.BordtE.A.PolsterB.M.NADPH oxidase- and mitochondria-derived reactive oxygen species in proinflammatory microglial activation: a bipartisan affair?201476344610.1016/j.freeradbiomed.2014.07.033425261025091898Open DOISearch in Google Scholar
Butturini E., Boriero D., Carcereri de Prati A., Mariotto S.: STAT1 drives M1 microglia activation and neuroinflammation under hypoxia. Arch Biochem Biophys 2019, 669, 22–30, doi: 10.1016/j.abb.2019.05.011.ButturiniE.BorieroD.Carcereride Prati A.MariottoS.STAT1 drives M1 microglia activation and neuroinflammation under hypoxia2019669223010.1016/j.abb.2019.05.01131121156Open DOISearch in Google Scholar
Choi Y.K., Park J.H., Yun J.A., Cha J.H., Kim Y., Won M.H., Kim K.W., Ha K.S., Kwon Y.G., Kim Y.M.: Heme oxygenase metabolites improve astrocytic mitochondrial function via a Ca2+-dependent HIF-1α/ERRα circuit. PloS one 2018, 13, e0202039, doi: 10.1371/journal.pone.0202039.ChoiY.K.ParkJ.H.YunJ.A.ChaJ.H.KimY.WonM.H.KimK.W.HaK.S.KwonY.G.KimY.M.Heme oxygenase metabolites improve astrocytic mitochondrial function via a Ca2+-dependent HIF-1α/ERRα circuit201813e020203910.1371/journal.pone.0202039611264030153269Open DOISearch in Google Scholar
Cunningham K.F., Beeson G.C., Beeson C.C., Baicu C.F., Zile M.R., McDermott P.J.: Estrogen-Related Receptor α (ERRα) is required for adaptive increases in PGC-1 isoform expression during electrically stimulated contraction of adult cardiomyocytes in sustained hypoxic conditions. Int J Cardiol 2015, 187, 393–400, doi: 10.1016/j.ijcard.2015.03.353.CunninghamK.F.BeesonG.C.BeesonC.C.BaicuC.F.ZileM.R.McDermottP.J.Estrogen-Related Receptor α (ERRα) is required for adaptive increases in PGC-1 isoform expression during electrically stimulated contraction of adult cardiomyocytes in sustained hypoxic conditions201518739340010.1016/j.ijcard.2015.03.35325841134Open DOISearch in Google Scholar
Gao X., Wu B., Fu Z., Zhang Z., Xu G.: Carvedilol abrogates hypoxia-induced oxidative stress and neuroinflammation in microglial BV2 cells. Eur J Pharmacol 2017, 814, 144–150, doi:10.1016/j.ejphar.2017.08.013.GaoX.WuB.FuZ.ZhangZ.XuG.Carvedilol abrogates hypoxia-induced oxidative stress and neuroinflammation in microglial BV2 cells201781414415010.1016/j.ejphar.2017.08.01328821450Open DOISearch in Google Scholar
Habib P., Slowik A., Zendedel A., Johann S., Dang J., Beyer C.: Regulation of hypoxia-induced inflammatory responses and M1-M2 phenotype switch of primary rat microglia by sex steroids. J Mol Neurosci 2014, 52, 277–285, doi: 10.1007/s12031-013-0137-y.HabibP.SlowikA.ZendedelA.JohannS.DangJ.BeyerC.Regulation of hypoxia-induced inflammatory responses and M1-M2 phenotype switch of primary rat microglia by sex steroids20145227728510.1007/s12031-013-0137-y24163150Open DOISearch in Google Scholar
Hashemi M.S., Ghaedi K., Salamian A., Karbalaie K., Emadi-Baygi M., Tanhaei S., Nasr-Esfahani M.H., Baharvand H.: Fndc5 knockdown significantly decreased neural differentiation rate of mouse embryonic stem cells. Neuroscience 2013, 231, 296–304, doi: 10.1016/j.neuroscience.2012.11.041.HashemiM.S.GhaediK.SalamianA.KarbalaieK.Emadi-BaygiM.TanhaeiS.Nasr-EsfahaniM.H.BaharvandH.Fndc5 knockdown significantly decreased neural differentiation rate of mouse embryonic stem cells201323129630410.1016/j.neuroscience.2012.11.04123219938Open DOISearch in Google Scholar
Hernandez-Gerez E., Fleming I.N., Parson S.H.: A role for spinal cord hypoxia in neurodegeneration. Cell Death Dis 2019, 10, 861, doi: 10.1038/s41419-019-2104-1.Hernandez-GerezE.FlemingI.N.ParsonS.H.A role for spinal cord hypoxia in neurodegeneration20191086110.1038/s41419-019-2104-1685389931723121Open DOISearch in Google Scholar
Jiao J., Wang Y., Ren P., Sun S., Wu M.: Necrosulfonamide Ameliorates Neurological Impairment in Spinal Cord Injury by Improving Antioxidative Capacity. Front Pharmacol 2019, 10, 1538, doi: 10.3389/fphar.2019.01538.JiaoJ.WangY.RenP.SunS.WuM.Necrosulfonamide Ameliorates Neurological Impairment in Spinal Cord Injury by Improving Antioxidative Capacity201910153810.3389/fphar.2019.01538696230331998134Open DOISearch in Google Scholar
Jones N.M., Bergeron M.: Hypoxia-induced ischemic tolerance in neonatal rat brain involves enhanced ERK1/2 signaling. J Neurochem 2004, 89, 157–167, doi: 10.1111/j.1471-4159.2004.02324.x.JonesN.M.BergeronM.Hypoxia-induced ischemic tolerance in neonatal rat brain involves enhanced ERK1/2 signaling20048915716710.1111/j.1471-4159.2004.02324.x15030400Open DOISearch in Google Scholar
Li Y., Chang Y., Ye N., Dai D., Chen Y., Zhang N., Sun G., Sun Y.: Advanced Glycation End Products Inhibit the Proliferation of Human Umbilical Vein Endothelial Cells by Inhibiting Cathepsin D. Int J Mol ScI 2017, 18, doi: 10.3390/ijms18020436.LiY.ChangY.YeN.DaiD.ChenY.ZhangN.SunG.SunY.Advanced Glycation End Products Inhibit the Proliferation of Human Umbilical Vein Endothelial Cells by Inhibiting Cathepsin D20171810.3390/ijms18020436534397028218663Open DOISearch in Google Scholar
Li X., Lou X., Xu S., Wang Q., Shen M., Miao J.: Knockdown of miR-372 Inhibits Nerve Cell Apoptosis Induced by Spinal Cord Ischemia/Reperfusion Injury via Enhancing Autophagy by Up-regulating Beclin-1. J Mol Neurosci 2018, 66, 437–444, doi: 10.1007/s12031-018-1179-y.LiX.LouX.XuS.WangQ.ShenM.MiaoJ.Knockdown of miR-372 Inhibits Nerve Cell Apoptosis Induced by Spinal Cord Ischemia/Reperfusion Injury via Enhancing Autophagy by Up-regulating Beclin-120186643744410.1007/s12031-018-1179-y30298297Open DOISearch in Google Scholar
Lian S., Wang D., Xu B., Guo W., Wang L., Li W., Ji H., Wang J., Kong F., Zhen L., Li S., Zhang L., Guo J., Yang H.: Prenatal cold stress: Effect on maternal hippocampus and offspring behavior in rats. Behav Brain Res 2018, 346, 1–10, doi: 10.1016/j.bbr.2018.02.002.LianS.WangD.XuB.GuoW.WangL.LiW.JiH.WangJ.KongF.ZhenL.LiS.ZhangL.GuoJ.YangH.Prenatal cold stress: Effect on maternal hippocampus and offspring behavior in rats201834611010.1016/j.bbr.2018.02.00229421306Open DOISearch in Google Scholar
Mitroshina E.V., Mishchenko T.A., Shishkina T.V., Vedunova M.V.: Role of Neurotrophic Factors BDNF and GDNF in Nervous System Adaptation to the Influence of Ischemic Factors. B Exp Biol Med 2019, 167, 574–579, doi: 10.1007/s10517-019-04574-1.MitroshinaE.V.MishchenkoT.A.ShishkinaT.V.VedunovaM.V.Role of Neurotrophic Factors BDNF and GDNF in Nervous System Adaptation to the Influence of Ischemic Factors201916757457910.1007/s10517-019-04574-131502136Open DOISearch in Google Scholar
O’Neill L.A., Pearce E.J.: Immunometabolism governs dendritic cell and macrophage function. J Exp Med 2016, 213, 15–23, doi: 10.1084/jem.20151570.O’NeillL.A.PearceE.J.Immunometabolism governs dendritic cell and macrophage function2016213152310.1084/jem.20151570471020426694970Open DOISearch in Google Scholar
Palazon A., Goldrath A.W., Nizet V., Johnson R.S.: HIF transcription factors, inflammation, and immunity. Immunity 2014, 41, 518–528, doi: 10.1016/j.immuni.2014.09.008.PalazonA.GoldrathA.W.NizetV.JohnsonR.S.HIF transcription factors, inflammation, and immunity20144151852810.1016/j.immuni.2014.09.008434631925367569Open DOISearch in Google Scholar
Peng L., Gao X., Duan L., Ren X., Wu D., Ding K.: Identification of pyrido[1,2-α]pyrimidine-4-ones as new molecules improving the transcriptional functions of estrogen-related receptor α. J Med Chem 2011, 54, 7729–7733, doi: 10.1021/jm200976s.PengL.GaoX.DuanL.RenX.WuD.DingK.Identification of pyrido[1,2-α]pyrimidine-4-ones as new molecules improving the transcriptional functions of estrogen-related receptor α2011547729773310.1021/jm200976s21958216Open DOISearch in Google Scholar
Ranhotra H.S.: The orphan estrogen-related receptor alpha and metabolic regulation: new frontiers. J Recept Signal Transduct Res 2015, 35, 565–568, doi: 10.3109/10799893.2015.1024853.RanhotraH.S.The orphan estrogen-related receptor alpha and metabolic regulation: new frontiers20153556556810.3109/10799893.2015.102485326037200Open DOISearch in Google Scholar
Rothhammer V., Borucki D.M., Tjon E.C., Takenaka M.C., Chao C.C., Ardura-Fabregat A., de Lima K.A., Gutiérrez-Vázquez C., Hewson P., Staszewski O., Blain M., Healy L., Neziraj T., Borio M., Wheeler M., Dragin L.L., Laplaud D.A., Antel J., Alvarez J.I., Prinz M., Quintana F.J.: Microglial control of astrocytes in response to microbial metabolites. Nature 2018, 557, 724–728, doi: 10.1038/s41586-018-0119-x.RothhammerV.BoruckiD.M.TjonE.C.TakenakaM.C.ChaoC.C.Ardura-FabregatA.de LimaK.A.Gutiérrez-VázquezC.HewsonP.StaszewskiO.BlainM.HealyL.NezirajT.BorioM.WheelerM.DraginL.L.LaplaudD.A.AntelJ.AlvarezJ.I.PrinzM.QuintanaF.J.Microglial control of astrocytes in response to microbial metabolites201855772472810.1038/s41586-018-0119-x642215929769726Open DOISearch in Google Scholar
Sarada S.K.S., Veeramohan H.P., Mathew T., Saumya S., Chitharanjan M.: Nifedipine inhibits hypoxia induced transvascular leakage through down regulation of NFkB. Resp Physiol Neurob 2012, 183, 26–34, doi: 10.1016/j.resp.2012.05.016.SaradaS.K.S.VeeramohanH.P.MathewT.SaumyaS.ChitharanjanM.Nifedipine inhibits hypoxia induced transvascular leakage through down regulation of NFkB2012183263410.1016/j.resp.2012.05.01622627105Open DOISearch in Google Scholar
Song Z.C., Ding L., Ren Z.Y., Sun X.S., Yang Q., Wang L., Feng M.J., Liu C.L., Wang J.T.: Effects of Src on cervical cancer cells proliferation and apoptosis through ERK signal transduction pathway. Chin J Endem 2017, 38, 1246–1251, doi: 10.3760/cma.j.issn.0254-6450.2017.09.021.SongZ.C.DingL.RenZ.Y.SunX.S.YangQ.WangL.FengM.J.LiuC.L.WangJ.T.Effects of Src on cervical cancer cells proliferation and apoptosis through ERK signal transduction pathway2017381246125110.3760/cma.j.issn.0254-6450.2017.09.02128910941Open DOISearch in Google Scholar
Tang X., Guo D., Lin C., Shi Z., Qian R., Fu W., Liu J., Li X., Fan L.: hCLOCK induction by hypoxia promotes inflammatory responses by activating the NF‑κB pathway. Mol Med Rep 2017, 15, 1401–1406, doi: 10.3892/mmr.2017.6127.TangX.GuoD.LinC.ShiZ.QianR.FuW.LiuJ.LiX.FanL.hCLOCK induction by hypoxia promotes inflammatory responses by activating the NF‑κB pathway2017151401140610.3892/mmr.2017.612728098888Open DOISearch in Google Scholar
Vernier M., Dufour C.R., McGuirk S., Scholtes C., Li X., Bourmeau G., Kuasne H., Park M., St-Pierre J., Audet-Walsh E., Giguère V.: Estrogen-related receptors are targetable ROS sensors. Gene Dev 2020, 34, 544–559, doi: 10.1101/gad.330746.119.VernierM.DufourC.R.McGuirkS.ScholtesC.LiX.BourmeauG.KuasneH.ParkM.St-PierreJ.Audet-WalshE.GiguèreV.Estrogen-related receptors are targetable ROS sensors20203454455910.1101/gad.330746.119711126132079653Open DOISearch in Google Scholar
Walker C.L., Walker M.J., Liu N.K., Risberg E.C., Gao X., Chen J., Xu X.M.: Systemic bisperoxovanadium activates Akt/mTOR, reduces autophagy, and enhances recovery following cervical spinal cord injury. PloS One 2012, 7, e30012, doi: 10.1371/journal.pone.0030012.WalkerC.L.WalkerM.J.LiuN.K.RisbergE.C.GaoX.ChenJ.XuX.M.Systemic bisperoxovanadium activates Akt/mTOR, reduces autophagy, and enhances recovery following cervical spinal cord injury20127e3001210.1371/journal.pone.0030012325464222253859Open DOISearch in Google Scholar
Wang B., Yan B., Song D., Ye X., Liu S.F.: Chronic intermittent hypoxia down-regulates endothelial nitric oxide synthase expression by an NF-κB-dependent mechanism. Sleep Med 2013, 14, 165–171, doi: 10.1016/j.sleep.2012.10.020.WangB.YanB.SongD.YeX.LiuS.F.Chronic intermittent hypoxia down-regulates endothelial nitric oxide synthase expression by an NF-κB-dependent mechanism20131416517110.1016/j.sleep.2012.10.02023266106Open DOISearch in Google Scholar
Wrann C.D., White J.P., Salogiannnis J., Laznik-Bogoslavski D., Wu J., Ma D., Lin J.D., Greenberg M.E., Spiegelman B.M.: Exercise induces hippocampal BDNF through a PGC-1α/FNDC5 pathway. Cell Metab 2013, 18, 649–659, doi: 10.1016/j.cmet.2013.09.008.WrannC.D.WhiteJ.P.SalogiannnisJ.Laznik-BogoslavskiD.WuJ.MaD.LinJ.D.GreenbergM.E.SpiegelmanB.M.Exercise induces hippocampal BDNF through a PGC-1α/FNDC5 pathway20131864965910.1016/j.cmet.2013.09.008398096824120943Open DOISearch in Google Scholar
Wu W.-M., Chen Z.-J., Jiang G.-M., Zhang K.-S., Liu Q., Liang S.-W., Zhou Y., Huang H.-B., Du J., Wang H.-S.: Inversse agonist of estogen-related receptor α suppresses the growth of triple negative breast cancer cells through ROS generation and interaction with multiple cell signaling pathways. Oncotarget 2016, 7, 12568–12581, doi: 10.18632/oncotarget.7276.WuW.-M.ChenZ.-J.JiangG.-M.ZhangK.-S.LiuQ.LiangS.-W.ZhouY.HuangH.-B.DuJ.WangH.-S.Inversse agonist of estogen-related receptor α suppresses the growth of triple negative breast cancer cells through ROS generation and interaction with multiple cell signaling pathways20167125681258110.18632/oncotarget.7276491430526871469Open DOISearch in Google Scholar
Zhao Y., Tian X., Liu G., Wang K., Xie Y., Qiu Y.: Berberine protects myocardial cells against anoxia-reoxygenation injury via p38 MAPK-mediated NF-κB signaling pathways. Exp Ther Med 2019, 17, 230–236, doi: 10.3892/etm.2018.6949.ZhaoY.TianX.LiuG.WangK.XieY.QiuY.Berberine protects myocardial cells against anoxia-reoxygenation injury via p38 MAPK-mediated NF-κB signaling pathways20191723023610.3892/etm.2018.6949630736130651787Open DOISearch in Google Scholar
Zheng Y., Han Z., Zhao H., Luo Y.: MAPK: A Key Player in the Development and Progression of Stroke. CNS Neurol Disord Drug Targets 2020, 19, 248–256, doi: 10.2174/1871527319666200613223018.ZhengY.HanZ.ZhaoH.LuoY.MAPK: A Key Player in the Development and Progression of Stroke20201924825610.2174/187152731966620061322301832533818Open DOISearch in Google Scholar
Zhu Y., Zhao L., Liu L., Gao P., Tian W., Wang X., Jin H., Xu H., Chen Q.: Beclin 1 cleavage by caspase-3 inactivates autophagy and promotes apoptosis. Protein Cell 2010, 1, 468–477, doi: 10.1007/s13238-010-0048-4.ZhuY.ZhaoL.LiuL.GaoP.TianW.WangX.JinH.XuH.ChenQ.Beclin 1 cleavage by caspase-3 inactivates autophagy and promotes apoptosis2010146847710.1007/s13238-010-0048-4487513121203962Open DOISearch in Google Scholar