Changes in the expression of TLR2 during the intestinal phase of trichinellosis
Publié en ligne: 21 avr. 2020
Pages: 269 - 274
Reçu: 22 mai 2019
Accepté: 03 avr. 2020
DOI: https://doi.org/10.2478/jvetres-2020-0027
Mots clés
© 2020 A. Wojtkowiak-Giera et al. published by Sciendo
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.
Introduction
Toll-like receptors (TLRs) play an important role in fast activation of the immune response to a variety of pathogens, including parasites. In this study, we focused on TLR2, because this receptor is one of the best known and most frequently analysed members of the TLR family. The aim of this study was to assess the effect of
Material and Methods
The experimental material consisted of isolates prepared from the intestines (jejunum and colon) of BALB/c mice infected with
Results
Our results based on quantitative real-time PCR showed that the mRNA level for TLR2 was statistically significantly higher in the jejuna of mice infected with
Conclusion
Our results indicate that infection with