<abstract xmlns="http://www.w3.org/1999/xhtml">

<sec><h3>Background</h3><p>Healthcare-associated infections (HAIs) can pose significant risks to patients with cardiovascular disease due to the compromised nature of their health and potential vulnerabilities. In order to reduce the incidence of HAIs and prevent the spread of antibiotic-resistant organisms, it is mandatory to develop surveillance systems.</p></sec>
<sec><h3>Methods</h3><p>We undertook a retrospective case–control study of all patients presenting HAIs who were admitted to the intensive care unit (ICU) to assess risk factors associated with death among patients with cardiovascular disease.</p></sec>
<sec><h3>Results</h3><p>Patients admitted to the ICU who died were more likely to present an infection with a multidrug-resistant bacterium, an infection with <italic>Acinetobacter baumannii</italic>, and to suffer from acute myocardial infarction. Among the patients enrolled in the study, a higher probability of death was also observed in association with certain Gram-negative pathogens such as <italic>Klebsiella pneumoniae</italic>, <italic>Acinetobacter baumannii</italic>, and <italic>Pseudomonas aeruginosa</italic>.</p></sec>
<sec><h3>Conclusion</h3><p>The longer the patient remains admitted in the ICU, the higher the risk of acquiring an infection that can often become fatal. A nosocomial infection, particularly in patients with cardiovascular disease, also increases the length of hospitalization, which will lead to increased expenditure. For this reason, new prophylactic methods and therapeutic approaches are needed, and researchers’ efforts should be directed in this direction.</p></sec>
</abstract>

BackgroundHealthcare-associated infections (HAIs) can pose significant risks to patients with cardiovascular disease due to the compromised nature of their health and potential vulnerabilities. In order to reduce the incidence of HAIs and prevent the spread of antibiotic-resistant organisms, it is mandatory to develop surveillance systems.
MethodsWe undertook a retrospective case–control study of all patients presenting HAIs who were admitted to the intensive care unit (ICU) to assess risk factors associated with death among patients with cardiovascular disease.
ResultsPatients admitted to the ICU who died were more likely to present an infection with a multidrug-resistant bacterium, an infection with Acinetobacter baumannii, and to suffer from acute myocardial infarction. Among the patients enrolled in the study, a higher probability of death was also observed in association with certain Gram-negative pathogens such as Klebsiella pneumoniae, Acinetobacter baumannii, and Pseudomonas aeruginosa.
ConclusionThe longer the patient remains admitted in the ICU, the higher the risk of acquiring an infection that can often become fatal. A nosocomial infection, particularly in patients with cardiovascular disease, also increases the length of hospitalization, which will lead to increased expenditure. For this reason, new prophylactic methods and therapeutic approaches are needed, and researchers’ efforts should be directed in this direction.

The Risk of Death among Patients with Healthcare-associated Infections and Cardiovascular Diseases Admitted to the Intensive Care Unit in Romania

“George Emil Palade” University of Medicine, Pharmacy, Science and Technology

Department of Anesthesia and Intensive Care

Department of Obstetrics and Gynecology, Emergency County Hospital

Journal of Cardiovascular Emergencies

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

BackgroundHealthcare-associated infections (HAIs) can pose significant risks to patients with cardiovascular disease due to the compromised nature of their...

The Risk of Death among Patients with Healthcare-associated Infections and Cardiovascular Diseases Admitted to the Intensive Care Unit in Romania

Article Category: Original Research

Publié en ligne: 22 janv. 2024

Pages: 71 - 77

Reçu: 15 déc. 2023

Accepté: 11 janv. 2024

DOI: https://doi.org/10.2478/jce-2024-0001

Mots clés
healthcare-associated infections, intensive care unit, cardiovascular diseases, multidrug-resistant bacteria

© 2024 Mihaela-Alexandra Budianu et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

The Risk of Death among Patients with Healthcare-associated Infections and Cardiovascular Diseases Admitted to the Intensive Care Unit in Romania

Article Category: Original Research

Publié en ligne: 22 janv. 2024

Pages: 71 - 77

Reçu: 15 déc. 2023

Accepté: 11 janv. 2024

DOI: https://doi.org/10.2478/jce-2024-0001

Mots cléshealthcare-associated infections, intensive care unit, cardiovascular diseases, multidrug-resistant bacteria

© 2024 Mihaela-Alexandra Budianu et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Mots clés
healthcare-associated infections, intensive care unit, cardiovascular diseases, multidrug-resistant bacteria