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Weekend Effect and Mortality Outcomes in Aortic Dissection: A Prospective Analysis

Cosmin Marian Banceu
Cosmin Marian Banceu
, 
Marius Harpa
Marius Harpa
, 
Klara Brinzaniuc
Klara Brinzaniuc
, 
Nicolae Neagu
Nicolae Neagu
, 
Dan Alexandru Szabo
Dan Alexandru Szabo
, 
Diana Mariana Banceu
Diana Mariana Banceu
, 
Hussam Al Hussein
Hussam Al Hussein
, 
Daiana Cristutiu
Daiana Cristutiu
, 
Alexandra Puscas
Alexandra Puscas
, 
Alexandru Stan
Alexandru Stan
, 
Marvin Oprean
Marvin Oprean
, 
Adrian Popentiu
Adrian Popentiu
, 
Marius Neamtu Halic
Marius Neamtu Halic
 et 
Horatiu Suciu
Horatiu Suciu
   | 30 avr. 2024
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Article Category: Research Article
Publié en ligne: 30 avr. 2024
Pages: 158 - 167
Reçu: 22 nov. 2023
Accepté: 18 mars 2024
DOI: https://doi.org/10.2478/jccm-2024-0014
Mots clés
© 2024 Cosmin Marian Banceu et al., published by Sciendo
This work is licensed under the Creative Commons Attribution 4.0 International License.

Fig. 1.

Flowchart of patients’ characteristics
Flowchart of patients’ characteristics

Fig. 2.

Kaplan–Meier representation of in-hospital mortality.
Kaplan–Meier representation of in-hospital mortality.

Mortality before surgery

Total present No. of death events Percent p-value
Log rank (Mantel–Cox) Breslow (generalized Wilcoxon) Tarone–Ware
Weekend 20 3 15.00 0.272 0.196 0.234
Weekday 104 9 8.65

In-hospital mortality

Total present No. of death events Percent Mean p-value
Estimate Std. error 95% confidence interval Log rank (Mantel–Cox) Breslow (generalized Wilcoxon) Tarone–Ware
Lower bound Upper bound
Weekend 20 5 25.00 18.138 5.350 7.653 28.623 0.260 0.209 0.232
Weekday 104 52 50.00 15.806 1.599 12.671 18.941

General characteristics measured before and after treatment (N = 124 patients)

Weekday Weekend Total p-value
Frequency (n) Percent (%) Frequency (n) Percent (%) Frequency (n) Percent (%)
Presentation 104 83.87 20 16.13 124 100.00 < 0.01
Gender Men 71 84.52 13 15.48 84 67.74 < 0.01
Women 33 82.50 7 17.50 40 32.26 < 0.01
Before Operation
  Hemopericardium 34 85.00 6 15.00 40 32.26 0.09
  Cardiac tamponade 3 72.22 5 27.78 18 14.51 < 0.01
  Cardiogenic shock 11 84.61 2 15.38 13 10.48 0.07
  Cardiac arrest 0 - 2 10.00 2 1.61 0.02
  Mortality before surgery 9 75.00 3 25.00 12 9.68 < 0.01
  Anticoagulation therapy 3 2.42 0 - 3 2.42 < 0.01
  Antiplatelet therapy 17 89.47 2 10.53 19 15.32 0.07
After Operation
  Ascending aorta replacement 63 84.00 12 16.00 75 60.48 < 0.01
  Hemiarch replacement 10 90.91 1 9.09 11 8.87 < 0.01
  Aortic valve replacement 21 87.50 3 12.50 24 19.35 0.09
  RCA reimplantation 7 77.78 2 22.22 9 7.26 < 0.01
  LCA reimplantation 6 75.00 2 25.00 8 6.45 < 0.01
  LAD bypass 4 100.00 0 - 4 3.23 0.06
  RCA bypass 6 85.71 1 14.29 7 5.65 0.07
  Bentall procedure 5 71.43 2 28.57 7 5.65 < 0.01

Admission timing laboratory data of patients with Stanford A dissection

Mean Minimum Maximum Std. deviation
Age 62.53 17 86 12.866
LVEF (%) 51.05 0 60 10.434
Creatinine level (mg/dL) 1.25 0.59 6.69 0.789
eGFR (mL/min/1.73 m2) 71.30 7.9 216.6 23.418
GOT (U/L) 79.82 10.0 2638.0 289.399
GPT (U/L) 71.13 6.0 2067.0 240.204
Hemoglobin (g/dL) 12.50 5.4 26.1 2.601
Thrombocytes (103/μL) 224.92 20.7 996.0 122.128
Leukocytes (103/μL) 11.33 2.0 24.4 4.838

Discharge mortality

Total present No. of death events Percent Mean p-value
Estimate Std. error 95% confidence interval Log rank (Mantel–Cox) Breslow (generalized Wilcoxon) Tarone–Ware
Lower bound Upper bound
Weekend 20 1 5.00 34.000 0.001 34.000 34.000 0.729 0.342 0.369
Weekday 104 10 9.61 29.456 1.912 25.710 33.203
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