<abstract xmlns="http://www.w3.org/1999/xhtml">

<p>Congenital heart malformations are cardiac and/or vascular structural abnormalities that appear before birth, the majority of which can be detected prenatally. The latest data from the literature were reviewed, with reference to the degree of prenatal diagnosis regarding congenital heart malformations, as well as its impact on the preoperative evolution and implicitly on mortality. Studies with a significant number of enrolled patients were included in the research. Prenatal congenital heart malformations detection rates were different, depending on the period in which the study took place, the level of the medical center, as well as on the size of enrolled groups. Prenatal diagnosis in critical malformations such as hypoplastic left heart syndrome, transposition of great arteries and totally aberrant pulmonary venous drainage has proven its usefulness, allowing an early surgical intervention, thus ensuring improved neurological development, increasing the survival rate and decreasing the rate of subsequent complications. Sharing the experience and results obtained by each individual therapeutic center will definitely lead to drawing clear conclusions regarding the clinical contribution of congenital heart malformations prenatal detection.</p></abstract>

Congenital heart malformations are cardiac and/or vascular structural abnormalities that appear before birth, the majority of which can be detected prenatally. The latest data from the literature were reviewed, with reference to the degree of prenatal diagnosis regarding congenital heart malformations, as well as its impact on the preoperative evolution and implicitly on mortality. Studies with a significant number of enrolled patients were included in the research. Prenatal congenital heart malformations detection rates were different, depending on the period in which the study took place, the level of the medical center, as well as on the size of enrolled groups. Prenatal diagnosis in critical malformations such as hypoplastic left heart syndrome, transposition of great arteries and totally aberrant pulmonary venous drainage has proven its usefulness, allowing an early surgical intervention, thus ensuring improved neurological development, increasing the survival rate and decreasing the rate of subsequent complications. Sharing the experience and results obtained by each individual therapeutic center will definitely lead to drawing clear conclusions regarding the clinical contribution of congenital heart malformations prenatal detection.

The Impact of Prenatal Diagnosis in the Evolution of Newborns with Congenital Heart Disease

The Journal of Critical Care Medicine

This work is licensed under the Creative Commons Attribution 4.0 International License.

Congenital heart malformations are cardiac and/or vascular structural abnormalities that appear before birth, the majority of which can be detected prenatally....

Author	Study period	Study design	Prenatal detection rate	Morbidity	Mortality
Chakraborty et al. [9]	10 years	retrospective	68,1 %	↓antibiotic therapy, inotropic need, liver/kidney dysfunction, acidosis	uninfluenced
van Velzen et al. [10]	10 years	prospective/ retrospective	59,7%	not mentioned	not mentioned
Gorla et al. [11]	18 years	retrospective	68,8%	not mentioned	uninfluenced
Gupta et al. [2]	5 years	retrospective	62 %	low doses of PGE low doses of iNO	uninfluenced
Suard et al. [12]	4 years	retrospective	71,5%	↑ duration of hospitalization in PICU	uninfluenced

The Impact of Prenatal Diagnosis in the Evolution of Newborns with Congenital Heart Disease

Article Category: Review

Publié en ligne: 08 févr. 2023

Pages: 6 - 11

Reçu: 09 sept. 2022

Accepté: 25 janv. 2023

DOI: https://doi.org/10.2478/jccm-2023-0007

Mots clés
congenital heart malformations, prenatal diagnosis, fetal echocardiography

© 2023 Daniela Toma, Elena Moldovan, Liliana Gozar, published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.

Influence of prenatal diagnosis on mortality and preoperative complications of the newborns with congenital heart disease – data from reviewed studies

The Impact of Prenatal Diagnosis in the Evolution of Newborns with Congenital Heart Disease

Article Category: Review

Publié en ligne: 08 févr. 2023

Pages: 6 - 11

Reçu: 09 sept. 2022

Accepté: 25 janv. 2023

DOI: https://doi.org/10.2478/jccm-2023-0007

Mots cléscongenital heart malformations, prenatal diagnosis, fetal echocardiography

© 2023 Daniela Toma, Elena Moldovan, Liliana Gozar, published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.

Influence of prenatal diagnosis on mortality and preoperative complications of the newborns with congenital heart disease – data from reviewed studies

Mots clés
congenital heart malformations, prenatal diagnosis, fetal echocardiography