<abstract xmlns="http://www.w3.org/1999/xhtml">

<p>The objective of this study was to determine the clinical picture of adult celiac disease in the population of eastern Algeria. We conducted a retrospective study on a sample of 156 patients in Internal Medicine service, Hepato-Gastroenterology Service, Endoscopy Service in the University Hospital BENBADIS - Constantine and the Military Regional University Hospital - Constantine. Our results have shown that, in this population, celiac disease can be manifested by a number of signs and related pathologies. A variety of digestive symptoms were reported, primarily chronic diarrhea (81.4%), abdominal pain (57.1%), anorexia (42.9%) and vomiting (48%). Extra-digestive symptoms manifested mainly as weight loss (90.4%), pallorous of skin and mucosa (84%), asthenia (60,3%), edema of the lower limbs (46.8%) and dehydration sings (37.8%). In addition, we noted biological disorders, the most common being hypocalcemia (77.4%) and hypoalbuminemia (57.7%), and a series associated pathologies namely: anemia (67.9%) and digestive diseases (38.46%). CD in adults in our population may express a variety of digestive and extra-digestive symptoms in addition to a number of associated pathologies.</p>
</abstract>

The objective of this study was to determine the clinical picture of adult celiac disease in the population of eastern Algeria. We conducted a retrospective study on a sample of 156 patients in Internal Medicine service, Hepato-Gastroenterology Service, Endoscopy Service in the University Hospital BENBADIS - Constantine and the Military Regional University Hospital - Constantine. Our results have shown that, in this population, celiac disease can be manifested by a number of signs and related pathologies. A variety of digestive symptoms were reported, primarily chronic diarrhea (81.4%), abdominal pain (57.1%), anorexia (42.9%) and vomiting (48%). Extra-digestive symptoms manifested mainly as weight loss (90.4%), pallorous of skin and mucosa (84%), asthenia (60,3%), edema of the lower limbs (46.8%) and dehydration sings (37.8%). In addition, we noted biological disorders, the most common being hypocalcemia (77.4%) and hypoalbuminemia (57.7%), and a series associated pathologies namely: anemia (67.9%) and digestive diseases (38.46%). CD in adults in our population may express a variety of digestive and extra-digestive symptoms in addition to a number of associated pathologies.

Characteristics of Adult Celiac Disease in Eastern Algeria

Pharmacology Toxicology Laboratory, Faculty of Nature and Life Sciences

Laboratory of Cellular and Molecular Biology, Faculty of Nature and Life Sciences

Department of Biochemistry and Biological Cellular and Molecular, Faculty of Nature and Life Sciences

Journal of Biomedical and Clinical Research

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

{"article-title":"Characteristics of Adult Celiac Disease in Eastern Algeria"}

The objective of this study was to determine the clinical picture of adult celiac disease in the population of eastern Algeria. We conducted a retrospective...

Characteristics of Adult Celiac Disease in Eastern Algeria

Publié en ligne: 10 août 2023

Pages: 25 - 32

Reçu: 04 janv. 2021

Accepté: 15 juin 2023

DOI: https://doi.org/10.2478/jbcr-2023-0003

Mots clés
adult coeliac disease, symptoms, associated conditions, Eastern Algeria

© 2023 Nousseiba Abed et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Characteristics of Adult Celiac Disease in Eastern Algeria

Publié en ligne: 10 août 2023

Pages: 25 - 32

Reçu: 04 janv. 2021

Accepté: 15 juin 2023

DOI: https://doi.org/10.2478/jbcr-2023-0003

Mots clésadult coeliac disease, symptoms, associated conditions, Eastern Algeria

© 2023 Nousseiba Abed et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Mots clés
adult coeliac disease, symptoms, associated conditions, Eastern Algeria