<abstract xmlns="http://www.w3.org/1999/xhtml">

<p>Granulomatosis with polyangiitis is a multisystem disease characterized by a necrotizing granulomatous vasculitis, typically associated with the presence of anti-neutrophil cytoplasmic antibodies. The lung is the most common organ involved in comparison to other vasculitis, but in the case presented by us the onset is otorhinolaryngology field, with a multitude of symptoms and immunological tests are initially negative. Over time, immunological tests become positive, but all this leading to a delay in diagnosis by 4 years and of course to a delay in treatment. In this paper we emphasize the usefulness of biopsy for diagnosis and use of anti-neutrophil cytoplasmic antibodies to classify the disease.</p>
</abstract>

Granulomatosis with polyangiitis is a multisystem disease characterized by a necrotizing granulomatous vasculitis, typically associated with the presence of anti-neutrophil cytoplasmic antibodies. The lung is the most common organ involved in comparison to other vasculitis, but in the case presented by us the onset is otorhinolaryngology field, with a multitude of symptoms and immunological tests are initially negative. Over time, immunological tests become positive, but all this leading to a delay in diagnosis by 4 years and of course to a delay in treatment. In this paper we emphasize the usefulness of biopsy for diagnosis and use of anti-neutrophil cytoplasmic antibodies to classify the disease.

Challenges in the Diagnosis of a Case of Granulomatosis with Polyangeitis

Central Military Emergency University Hospital Carol Davila

Internal Medicine

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

{"article-title":"Challenges in the Diagnosis of a Case of Granulomatosis with Polyangeitis"}

Granulomatosis with polyangiitis is a multisystem disease characterized by a necrotizing granulomatous vasculitis, typically associated with the presence of...

Challenges in the Diagnosis of a Case of Granulomatosis with Polyangeitis

Publié en ligne: 13 sept. 2021

Pages: 59 - 66

DOI: https://doi.org/10.2478/inmed-2021-0175

Mots clés
Vasculitis, granulomatosis with polyangiitis, anti-neutrophil cytoplasmic antibody

© 2021 Daniela Anghel et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Challenges in the Diagnosis of a Case of Granulomatosis with Polyangeitis

Publié en ligne: 13 sept. 2021

Pages: 59 - 66

DOI: https://doi.org/10.2478/inmed-2021-0175

Mots clésVasculitis, granulomatosis with polyangiitis, anti-neutrophil cytoplasmic antibody

© 2021 Daniela Anghel et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Mots clés
Vasculitis, granulomatosis with polyangiitis, anti-neutrophil cytoplasmic antibody