The Uncertain Link Between Gallstone Disease and Colorectal Cancer

1. Mármol I, Sánchez-de-Diego C, Dieste AP, Cerrada E, Yoldi MJR. Colorectal carcinoma: A general overview and future perspectives in colorectal cancer. Int J Mol Sci. 2017. doi:10.3390/ijms1801019710.3390/ijms18010197529782828106826 Search in Google Scholar

2. Simon K. Colorectal cancer development and advances in screening. Clin Interv Aging. 2016. doi:10.2147/CIA.S10928510.2147/CIA.S109285495836527486317 Search in Google Scholar

3. Arnold M, Sierra MS, Laversanne M, Soerjomataram I, Jemal A, Bray F. Global patterns and trends in colorectal cancer incidence and mortality. Gut. 2017. doi:10.1136/gutjnl-2015-31091210.1136/gutjnl-2015-31091226818619 Search in Google Scholar

4. American Cancer Society. Cancer Facts & Figures 2016. Cancer Facts Fig 2016. 2016. doi:10.1097/01.NNR.0000289503.22414.7910.1097/01.NNR.0000289503.22414.7917846553 Search in Google Scholar

5. Ward HA, Murphy N, Weiderpass E, et al. Gallstones and incident colorectal cancer in a large pan-European cohort study. Int J Cancer. 2019. doi:10.1002/ijc.3209010.1002/ijc.3209030585640 Search in Google Scholar

6. Nogueira L, Freedman ND, Engels EA, Warren JL, Castro F, Koshiol J. Gallstones, cholecystectomy, and risk of digestive system cancers. Am J Epidemiol. 2014. doi:10.1093/aje/kwt32210.1093/aje/kwt322585608624470530 Search in Google Scholar

7. Chiong C, Cox MR, Eslick GD. Gallstone disease is associated with rectal cancer: A meta-analysis. Scand J Gastroenterol. 2012. doi:10.3109/00365521.2012.66053810.3109/00365521.2012.66053822369489 Search in Google Scholar

8. Chen Y, Wang Z. Cholelithiasis and cholecystectomy for colorectal cancer: a retrospective analysis. Zhonghua Wai Ke Za Zhi. 1998. Search in Google Scholar

9. Rezasoltani S, Sadeghi A, Radinnia E, et al. The association between gut microbiota, cholesterol gallstones, and colorectal cancer. Gastroenterol Hepatol from Bed to Bench. 2019. doi:10.22037/ghfbb. v12i0.1823 Search in Google Scholar

10. Coccolini F, Catena F, Pisano M, et al. Open versus laparoscopic cholecystectomy in acute cholecystitis. Systematic review and meta-analysis. Int J Surg. 2015. doi:10.1016/j.ijsu.2015.04.08310.1016/j.ijsu.2015.04.08325958296 Search in Google Scholar

11. Cook JW, Kennaway EL, Kennaway NM. Production of tumours in mice by deoxycholic acid [10]. Nature. 1940. doi:10.1038/145627a010.1038/145627a0 Search in Google Scholar

12. Russell DW. The Enzymes, Regulation, and Genetics of Bile Acid Synthesis. Annu Rev Biochem. 2003. doi:10.1146/annurev.biochem.72.121801.16171210.1146/annurev.biochem.72.121801.16171212543708 Search in Google Scholar

13. Fiorucci S, Cipriani S, Mencarelli A, Renga B, Distrutti E, Baldelli F. Counter-Regulatory Role of Bile Acid Activated Receptors in Immunity and Inflammation. Curr Mol Med. 2012. doi:10.2174/15665241079223131210.2174/156652410792231312 Search in Google Scholar

14. Redinger RN. The coming of age of our understanding of the enterohepatic circulation of bile salts. Am J Surg. 2003. doi:10.1016/S0002-9610(02)01212-610.1016/S0002-9610(02)01212-6 Search in Google Scholar

15. Ridlon JM, Kang DJ, Hylemon PB. Bile salt biotransformations by human intestinal bacteria. J Lipid Res. 2006. doi:10.1194/jlr.R500013-JLR20010.1194/jlr.R500013-JLR200 Search in Google Scholar

16. Nagengast FM, Grubben MJAL, van Munster IP. Role of bile acids in colorectal carcinogenesis. Eur J Cancer. 1995. doi:10.1016/0959-8049(95)00216-610.1016/0959-8049(95)00216-6 Search in Google Scholar

17. Hill MJ. Bile flow and colon cancer. Mutat Res Genet Toxicol. 1990. doi:10.1016/0165-1110(90)90023-510.1016/0165-1110(90)90023-5 Search in Google Scholar

18. Magalhães B, Peleteiro B, Lunet N. Dietary patterns and colorectal cancer: Systematic review and meta-analysis. Eur J Cancer Prev. 2012. doi:10.1097/CEJ.0b013e328347224110.1097/CEJ.0b013e3283472241 Search in Google Scholar

19. Louis P, Hold GL, Flint HJ. The gut microbiota, bacterial metabolites and colorectal cancer. Nat Rev Microbiol. 2014. doi:10.1038/nrmicro334410.1038/nrmicro3344 Search in Google Scholar

20. Hofmann AF, Cravetto C, Molino G, Belforte G, Bona B. Simulation of the metabolism and enterohepatic circulation of endogenous deoxycholic acid in humans using a physiologic pharmacokinetic model for bile acid metabolism. Gastroenterology. 1987. doi:10.1016/0016-5085(87)90430-610.1016/0016-5085(87)90430-6 Search in Google Scholar

21. Wilpart M. Co-mutagenicity of bile acids: Structure-activity relations. Eur J Cancer Prev. 1991. doi:10.1097/00008469-199110002-0000810.1097/00008469-199110002-000081842731 Search in Google Scholar

22. Hylemon PB, Zhou H, Pandak WM, Ren S, Gil G, Dent P. Bile acids as regulatory molecules. J Lipid Res. 2009;50(8):1509-1520. doi:10.1194/jlr.R900007-JLR20010.1194/jlr.R900007-JLR200272404719346331 Search in Google Scholar

23. Chen X, Resh MD. Cholesterol depletion from the plasma membrane triggers ligand-independent activation of the epidermal growth factor receptor. J Biol Chem. 2002. doi:10.1074/jbc.M20832720010.1074/jbc.M208327200 Search in Google Scholar

24. Payne C. Hydrophobic bile acids, genomic instability, Darwinian selection, and colon carcinogenesis. Clin Exp Gastroenterol. 2008. doi:10.2147/ceg.s434310.2147/CEG.S4343 Search in Google Scholar

25. Hylemon PB, Zhou H, Pandak WM, Ren S, Gil G, Dent P. Bile acids as regulatory molecules. J Lipid Res. 2009. doi:10.1194/jlr.R900007-JLR20010.1194/jlr.R900007-JLR200 Search in Google Scholar

26. Morotomi M, Guillem JG, LoGerfo P, Weinstein IB. Production of Diacylglycerol, an Activator of Protein Kinase C, by Human Intestinal Microflora. Cancer Res. 1990. J Lipid Res. 1997. Search in Google Scholar

28. Bernstein H, Bernstein C, Payne CM, Dvorakova K, Garewal H. Bile acids as carcinogens in human gastrointestinal cancers. Mutat Res - Rev Mutat Res. 2005. doi:10.1016/j.mrrev.2004.08.00110.1016/j.mrrev.2004.08.001 Search in Google Scholar

29. Armaghany T, Wilson JD, Chu Q, Mills G. Genetic alterations in colorectal cancer. Gastrointest Cancer Res. 2012. Search in Google Scholar

30. Portincasa P, Moschetta A, Palasciano G. Cholesterol gallstone disease. Lancet. 2006. doi:10.1016/S0140-6736(06)69044-210.1016/S0140-6736(06)69044-2 Search in Google Scholar

31. Stinton LM, Shaffer EA. Epidemiology of gallbladder disease: Cholelithiasis and cancer. Gut Liver. 2012. doi:10.5009/gnl.2012.6.2.17210.5009/gnl.2012.6.2.172334315522570746 Search in Google Scholar

32. Sherlock S, Dooley J (James S. Diseases of the Liver and Biliary System. Blackwell Science; 2002.10.1002/9780470986820 Search in Google Scholar

33. Wang DQH, Afdhal NH. Genetic analysis of cholesterol gallstone formation: Searching for Lith (gallstone) genes. Curr Gastroenterol Rep. 2004. doi:10.1007/s11894-004-0042-110.1007/s11894-004-0042-115191694 Search in Google Scholar

34. Saklayen MG. The Global Epidemic of the Metabolic Syndrome. Curr Hypertens Rep. 2018. doi:10.1007/s11906-018-0812-z10.1007/s11906-018-0812-z586684029480368 Search in Google Scholar

35. Njeze GE. Gallstones. Niger J Surg Off Publ Niger Surg Res Soc. 2013;19(2):49. doi:10.4103/1117-6806.119236 Search in Google Scholar

36. Søreide K. Gallstone Disease and Cancer Risk: Finding the Bug in the System. Gastroenterology. 2017. doi:10.1053/j.gastro.2017.04.02810.1053/j.gastro.2017.04.02828461193 Search in Google Scholar

37. Das KM, Vecchi M, Sakamaki S. A shared and unique epitope(s) on human colon, skin, and biliary epithelium detected by a monoclonal antibody. Gastroenterology. 1990. doi:10.1016/0016-5085(90)90839-S10.1016/0016-5085(90)90839-S Search in Google Scholar

38. Chiong C, Cox MR, Eslick GD. Gallstones are associated with colonic adenoma: A meta-analysis. World J Surg. 2012. doi:10.1007/s00268-012-1646-510.1007/s00268-012-1646-522562454 Search in Google Scholar

39. Shabanzadeh DM, Sørensen LT, Jørgensen T. Association Between Screen-Detected Gallstone Disease and Cancer in a Cohort Study. Gastroenterology. 2017. doi:10.1053/j.gastro.2017.02.01310.1053/j.gastro.2017.02.01328238770 Search in Google Scholar

40. Mamianetti A, Garrido D, Carducci CN, Vescina MC. Fecal bile acid excretion profile in gallstone patients. Medicina (B Aires). 1999. Search in Google Scholar

41. Herrera J, Amigo L, Husche C, et al. Fecal bile acid excretion and messenger RNA expression levels of ileal transporters in high risk gallstone patients. Lipids Health Dis. 2009. doi:10.1186/1476-511X-8-5310.1186/1476-511X-8-53279749619995447 Search in Google Scholar

42. Keren N, Konikoff FM, Paitan Y, et al. Interactions between the intestinal microbiota and bile acids in gallstones patients. Environ Microbiol Rep. 2015. doi:10.1111/1758-2229.1231910.1111/1758-2229.1231926149537 Search in Google Scholar

43. Borzellino G, Cordiano C. Biliary Lithiasis: Basic Science, Current Diagnosis and Management.; 2008. doi:10.1007/978-88-470-0763-510.1007/978-88-470-0763-5 Search in Google Scholar

44. Shukla VK, Tiwari SC, Roy SK. Biliary bile acids in cholelithiasis and carcinoma of the gall bladder. Eur J Cancer Prev. 1993. doi:10.1097/00008469-199303000-0000810.1097/00008469-199303000-000088461866 Search in Google Scholar

45. Caddy GR, Tham TCK. Symptoms, diagnosis and endoscopic management of common bile duct stones. Best Pract Res Clin Gastroenterol. 2006. doi:10.1016/j.bpg.2006.03.00210.1016/j.bpg.2006.03.00217127190 Search in Google Scholar

46. Grivennikov SI, Greten FR, Karin M. Immunity, Inflammation, and Cancer. Cell. 2010. doi:10.1016/j.cell.2010.01.02510.1016/j.cell.2010.01.025286662920303878 Search in Google Scholar

47. Gibney EJ. Asymptomatic gallstones. Br J Surg. 1990. doi:10.1002/bjs.180077040510.1002/bjs.18007704052187558 Search in Google Scholar

48. Tait N, Little JM. Fortnightly Review: The treatment of gall stones. BMJ. 1995;311(6997):99. doi:10.1136/bmj.311.6997.9910.1136/bmj.311.6997.9925501527613411 Search in Google Scholar

49. Di Ciaula A, Wang DQH, Wang HH, Bonfrate L, Portincasa P. Targets for current pharmacologic therapy in cholesterol gallstone disease. Gastroenterol Clin North Am. 2010. doi:10.1016/j.gtc.2010.02.00510.1016/j.gtc.2010.02.005291545420478485 Search in Google Scholar

50. Barrasa JI, Olmo N, Lizarbe MA, Turnay J. Bile acids in the colon, from healthy to cytotoxic molecules. Toxicol Vitr. 2013. doi:10.1016/j.tiv.2012.12.02010.1016/j.tiv.2012.12.02023274766 Search in Google Scholar

51. Tavani A, Rosato V, Di Palma F, et al. History of cholelithiasis and cancer risk in a network of case-control studies. Ann Oncol. 2012. doi:10.1093/annonc/mdr58110.1093/annonc/mdr58122231026 Search in Google Scholar

52. Clemente JC, Ursell LK, Parfrey LW, Knight R. The Impact of the Gut Microbiota on Human Health: An Integrative View - 1-s2.0-S0092867412001043-main.pdf. Cell. 2012. doi:10.1016/j.cell.2012.01.03510.1016/j.cell.2012.01.035505001122424233 Search in Google Scholar

53. Wu H, Tremaroli V, Bäckhed F. Linking Microbiota to Human Diseases: A Systems Biology Perspective. Trends Endocrinol Metab. 2015. doi:10.1016/j.tem.2015.09.01110.1016/j.tem.2015.09.01126555600 Search in Google Scholar

54. Sobhani I, Tap J, Roudot-Thoraval F, et al. Microbial dysbiosis in colorectal cancer (CRC) patients. PLoS One. 2011. doi:10.1371/journal.pone.001639310.1371/journal.pone.0016393302930621297998 Search in Google Scholar

55. David LA, Maurice CF, Carmody RN, et al. Diet rapidly and reproducibly alters the human gut microbiome. Nature. 2014. doi:10.1038/nature1282010.1038/nature12820395742824336217 Search in Google Scholar