Determination of plasma level of D-dimers in patient with acute ischemic stroke can be used as a potential predictor of survival and correlated with the degree of disability of the patient. This study shows a correlation between the serum level of D-dimers in the diabetic patients with acute ischemic stroke, which may result that the level of D-dimers could be a good predictor of survival in acute ischemic stroke but not a predictor of disability and prognosis.