<abstract xmlns="http://www.w3.org/1999/xhtml"><p>The serotoninergic and FMRFamidergic nervous system of the attachment organs of trematodes were examined using immunocytochemical techniques and confocal scanning laser microscopy. Adult trematodes from eight families as well as cercariae and metacercariae from ten families were studied. TRITC-conjugated phalloidin was used to stain the muscle fibres. The serotonin- and FMRFamide-immunoreactive (IR) nerve cells and fibres were revealed to be near the muscle fibres of the oral and ventral suckers of the trematodes and their larvae. The results indicate the important role of neurotransmitters, serotonin and neuropeptide FMRFamide in the regulation of muscle activity in the attachment organs of trematodes and can be considered in perspective for the development of new anthelmintic drugs, which can interrupt the function of the attachment organs of the parasites.</p></abstract>

The serotoninergic and FMRFamidergic nervous system of the attachment organs of trematodes were examined using immunocytochemical techniques and confocal scanning laser microscopy. Adult trematodes from eight families as well as cercariae and metacercariae from ten families were studied. TRITC-conjugated phalloidin was used to stain the muscle fibres. The serotonin- and FMRFamide-immunoreactive (IR) nerve cells and fibres were revealed to be near the muscle fibres of the oral and ventral suckers of the trematodes and their larvae. The results indicate the important role of neurotransmitters, serotonin and neuropeptide FMRFamide in the regulation of muscle activity in the attachment organs of trematodes and can be considered in perspective for the development of new anthelmintic drugs, which can interrupt the function of the attachment organs of the parasites.

Serotonin and neuropeptide FMRFamide in the attachment organs of trematodes

A.N. Severtsov Institute of Ecology and Evolution of Russian Academy of Sciences, Center of Parasitology

Institute of Cell Biophysics of Russian Academy of Sciences

Helminthologia

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

{"article-title":"Serotonin and neuropeptide FMRFamide in the attachment organs of trematodes"}

The serotoninergic and FMRFamidergic nervous system of the attachment organs of trematodes were examined using immunocytochemical techniques and confocal...

Serotonin and neuropeptide FMRFamide in the attachment organs of trematodes

Publié en ligne: 28 juil. 2018

Pages: 185 - 194

Reçu: 02 avr. 2018

Accepté: 05 juin 2018

DOI: https://doi.org/10.2478/helm-2018-0022

Mots clés
Trematodes, attachment organs, neurotransmitters, serotonin, FMRFamide, nervous system

© 2018 N. B. Terenina et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Serotonin and neuropeptide FMRFamide in the attachment organs of trematodes

Publié en ligne: 28 juil. 2018

Pages: 185 - 194

Reçu: 02 avr. 2018

Accepté: 05 juin 2018

DOI: https://doi.org/10.2478/helm-2018-0022

Mots clésTrematodes, attachment organs, neurotransmitters, serotonin, FMRFamide, nervous system

© 2018 N. B. Terenina et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Mots clés
Trematodes, attachment organs, neurotransmitters, serotonin, FMRFamide, nervous system