Analysis of Sister Chromatid Exchanges and Proliferation of Human Peripheral Blood Lymphocytes Exposed to Epoxiconazole

1. Amara, A., Quiniou, F., Durand, G., EL Bour, M., Boudabous, A., Hourmant, A., 2013: Toxicity of epoxiconazole to the marine diatom Chaetoceros calcitrans: Influence of growth conditions and algal development stage. Water Air Soil Pollut., 224, 1—9.10.1007/s11270-012-1417-9Search in Google Scholar

2. EPA (Office of Prevention, Pesticides and Toxic Substances), 2006:Pesticide Fact Sheet: Epoxiconazole, 21 pp.Search in Google Scholar

3. Heise, T., Schmidt, F., Knebel, C., Rieke, S., Haider, W., Pfeil, R., et al., 2015: Hepatotoxic effects of (tri)azole fungicides in a broad dose range. Arch. Toxicol., 89, 2105—2117.10.1007/s00204-014-1336-125182419Search in Google Scholar

4. Herrera-Martínez, A. D., Feelders, R., Castano, J., Dogan, F., Koetsvelt, P., Hofland, L., 2017: Effects of ketoconazole on ACTH-producing and non ACTH-producing neuroendocrine tumour cells. Endocrine abstracts, 49, 182.10.1530/endoabs.49.EP182Search in Google Scholar

5. Lebailly, P., Gladys, M., Herin, F., Lecluse, Y., Sales, B., Boutet-Robinet, E., 2015: DNA damage in B and T lymphocytes of farmers during one pesticide spraying season. Int. Arch. Occup. Environ. Health, 88, 963—972.10.1007/s00420-015-1024-3456444025647545Search in Google Scholar

6. Pérez-Rivera, A. A., Hu, T., Aardema, M. J., Nash, J. F., 2009: Evaluation of the genotoxicity of the imidazole anti-fungal climbazole: Comparison to published results for other azole compounds. Mutat. Res., 672, 27—39.10.1016/j.mrgentox.2008.09.01118950734Search in Google Scholar

7. Roelofs, M., Temming, A. R., Piersma, A. H., Van Den Berg, M., Van Dursen, M. B. M., 2014: Conazole fungicides inhibit Leydig cell testosterone secretion and androgen receptor activation in vitro. Toxicol. Rep., 1, 271—283.10.1016/j.toxrep.2014.05.006559841728962244Search in Google Scholar

8. Ross, J., Moore, T., Leavitt, S. A., 2009:In vivo mutagenicity of conazole fungicides correlates with tumorigenicity. Mutagenesis, 24, 149—152.10.1093/mutage/gen06219028983Search in Google Scholar

9. Ross, J., Leavitt, S. A., Schmid, J. E., Nelson, G. B., 2012: Quantitative changes in endogenous DNA adducts correlate with conazole in vivo mutagenicity and tumorigenicity. Mutagenesis, 27, 541—549.10.1093/mutage/ges01722492202Search in Google Scholar

10. Schwarzbacherová, V., Šiviková, K., Drážovská, M., Dianovský, J., 2015: Evaluation of DNA damage and cytotoxicity induced by triazole fungicide in cultured bovine lymphocytes. Caryologia, 68, 233—238.10.1080/00087114.2015.1032613Search in Google Scholar

11. Šiviková, K., Holečková, B., Schwarzbacherová, V., Galdíková, M., Dianovský, J. 2018: Potential chromosome damage, cell-cycle kinetics/and apoptosis induced by epoxiconazole in bovine peripheral lymphocytes in vitro. Chemosphere, 193, 82—88.10.1016/j.chemosphere.2017.11.008Search in Google Scholar

12. Taxvig, C., Hass, U., Axelstad, M., Dalgaard, M., Boberg, J., Andeasen, H. L., et al., 2007: Endocrine-disrupting activities in vivo of the fungicides tebuconazole and epoxiconazole. Toxicol. Sci. Off. J. Soc. Toxicol., 100, 464—473.10.1093/toxsci/kfm22717785682Search in Google Scholar

13. Terzoudi, G. I., Malik, S. I., Pantelias, G. E., Margaritis, K., Manola, K., Makropoulos, W., 2003: A new cytogenetic approach for the evaluation of mutagenic potential of chemicals that induce cell cycle arrest in the G₂ phase. Mutagenesis, 18, 539—543.10.1093/mutage/geg03414614190Search in Google Scholar

14. Yilmaz, S., Aksoy, H., Unal, F., Celik, M., Yuzbaloglu, D., 2008: Genotoxic action of fungicide Conan 5FL (hexaconazole) on mammalian cells in vivo and in vitro. Russian J. Genet., 44, 273—278.10.1134/S1022795408030058Search in Google Scholar

15. Zhu, B., Liu, L., Gong, Y. X., Ling, F., Wang, G. X., 2014: Triazole-induced toxicity in developing rare minnow (Gobiocypris rarus) embryos. Environ. Sci. Pollut. Res. Int., 21, 13625—13635.10.1007/s11356-014-3317-625028328Search in Google Scholar

16. Lv, X., Pan, L., Wang, J., Lu, L., Yan, W., Zhu, Y., et al., 2017: Effects of triazole fungicides on androgenic disruption and CYP3A4 enzyme activity. Environ. Pollut., 222, 504—512.10.1016/j.envpol.2016.11.05128012672Search in Google Scholar