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Advanced glycation end products of dietary origin and their association with inflammation in diabetes – A minireview

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Aschner M, Skalny AV, Gritsenko VA, Kartashova OL, Santamaria A, Rocha JBT, Spandidos DA, Zaitseva IP, Tsatsakis A, Tinkov AA. Role of gut microbiota in the modulation of the health effects of advanced glycation end-products (Review). Int J Mol Med 51, 44, 2023.Search in Google Scholar

Bettiga A, Fiorio F, Di Marco F, Trevisani F, Romani A, Porrini E, Salonia A, Montorsi F, Vago R. The modern Western diet rich in advanced glycation end-products (AGEs): an overview of its impact on obesity and early progression of renal pathology. nutrients 11, 1748, 2019.Search in Google Scholar

Boyer F, Vidot JB, Dubourg AG, Rondeau P, Essop MF, Bourdon E. Oxidative stress and adipocyte biology: focus on the role of AGEs. Oxid Med Cell Longev 2015, 534873, 2015.Search in Google Scholar

Bui TPN, Troise AD, Fogliano V, de Vos WM. Anaerobic degradation of N-ε-carboxymethyllysine, a major glycation end-product, by human intestinal bacteria. J Agric Food Chem 67, 6594–6602, 2019.Search in Google Scholar

Capurso C, Bellanti F, Lo Buglio A, Vendemiale G. The Mediterranean diet slows down the progression of aging and helps to prevent the onset of frailty: A narrative review. Nutrients 12, 35, 2019.Search in Google Scholar

Chen JH, Lin X, Bu C, Zhang X. Role of advanced glycation end products in mobility and considerations in possible dietary and nutritional intervention strategies. Nutr Metab (Lond) 15, 72, 2018.Search in Google Scholar

Chrysanthou M, Miro Estruch I, Rietjens IMCM, Wichers HJ, Hoppenbrouwers T. In vitro methodologies to study the role of advanced glycation end products (AGEs) in neurodegeneration. Nutrients 14, 363, 2022.Search in Google Scholar

Delgado-Andrade C. Carboxymethyl-lysine: thirty years of investigation in the field of AGE formation. Food Funct 7, 46–57, 2016.Search in Google Scholar

Dong H, Zhang Y, Huang Y, Deng H. Pathophysiology of RAGE in inflammatory diseases. Front Immunol 13, 931473, 2022.Search in Google Scholar

Egana-Gorrono L, Lopez-Diez R, Yepuri G, Ramirez LS, Reverdatto S, Gugger PF, Shekhtman A, Ramasamy R, Schmidt AM. Receptor for advanced glycation end products (RAGE) and mechanisms and therapeutic opportunities in diabetes and cardiovascular disease: insights from human subjects and animal models. Front Cardiovasc Med 7, 37, 2020.Search in Google Scholar

Ellingson AJ, Pancheri NM, Schiele NR. Regulators of collagen crosslinking in developing and adult tendons. Eur Cell Mater 43, 130–152, 2022.Search in Google Scholar

Finicelli M, Di Salle A, Galderisi U, Peluso G. The Mediterranean diet: An update of the clinical trials. Nutrients 14, 2956, 2022.Search in Google Scholar

Finucane OM, Lyons CL, Murphy AM, Reynolds CM, Klinger R, Healy NP, Cooke AA, Coll RC, McAllan L, Nilaweera KN, O’Reilly ME, Tierney AC, Morine MJ, Alcala-Diaz JF, Lopez-Miranda J, O’Connor DP, O’Neill LA, Mc-Gillicuddy FC, Roche HM. Monounsaturated fatty acid-enriched high-fat diets impede adipose NLRP3 inflammasome-mediated IL-1β secretion and insulin resistance despite obesity. Diabetes 64, 2116–2128, 2015. Search in Google Scholar

Forster A, Kuhne Y, Henle T. Studies on absorption and elimination of dietary Maillard reaction products. Ann N Y Acad Sci 1043, 474–481, 2005.Search in Google Scholar

Fotheringham AK, Gallo LA, Borg DJ, Forbes JM. Advanced glycation end products (AGEs) and chronic kidney disease: does the modern diet AGE the kidney? Nutrients 14, 2675, 2022.Search in Google Scholar

Garay-Sevilla M, Beeri M, de la Maza M, Rojas A, Salazar-Villanea S, Uribarri J. The potential role of dietary advanced glycation end products in the development of chronic non-infectious diseases: A narrative review. Nutr. Res. Rev 33, 298–311, 2020.Search in Google Scholar

Garay-Sevilla M, Rojas A, Portero-Otin M, Uribarri J. Dietary AGEs as exogenous boosters of inflammation. Nutrients 13, 2802, 2021.Search in Google Scholar

Gasiorowski K, Brokos B, Echeverria V, Barreto GE, Leszek J. RAGE-TLR crosstalk sustains chronic inflammation in neurodegeneration. Mol Neurobiol 55, 1463–1476, 2018.Search in Google Scholar

Gautieri A, Passini FS, Silvan U, Guizar-Sicairos M, Carimati G, Volpi P, Moretti M, Schoenhuber H, Redaelli A, Berli M, Snedeker JG. Advanced glycation end-products: Mechanics of aged collagen from molecule to tissue. Matrix Biol 59, 95–108, 2017.Search in Google Scholar

Gil A, Bengmark S. Productos finales de la glicacion y de la lipoxidacion como amplificadores de la inflamacion: papel de los alimentos [Advanced glycation and lipoxidation end products-amplifiers of inflammation: the role of food]. Nutr Hosp 22, 625–640, 2007.Search in Google Scholar

Gill V, Kumar V, Singh K, Kumar A, Kim JJ. Advanced glycation end products (AGEs) may be a striking link between modern diet and health. Biomolecules 9, 888, 2019.Search in Google Scholar

Guan SS, Sheu ML, Yang RS, Chan DC, Wu CT, Yang TH, Chiang CK, Liu SH. The pathological role of advanced glycation end products-downregulated heat shock protein 60 in islet β-cell hypertrophy and dysfunction. Oncotarget 7, 23072–23087, 2016.Search in Google Scholar

Guerrero-Hernandez A, Leon-Aparicio D, Chavez-Reyes J, Olivares-Reyes JA, DeJesus S. Endoplasmic reticulum stress in insulin resistance and diabetes. Cell Calcium 56, 311–322, 2014.Search in Google Scholar

Guilbaud A, Niquet-Leridon C, Boulanger E, Tessier FJ. How can diet affect the accumulation of advanced glycation end-products in the human body? Foods 5, 84, 2016.Search in Google Scholar

Gupta A, Uribarri J. Dietary advanced glycation end products and their potential role in cardiometabolic disease in children. Horm Res Paediatr 85, 291–300, 2016.Search in Google Scholar

Gupta S, Dominguez M, Golestaneh L. Diabetic kidney disease: An update. Med Clin North Am 107, 689–705, 2023. Harmel R, Fiedler D. Features and regulation of non-enzymatic post-translational modifications. Nat Chem Biol 14, 244–252, 2018.Search in Google Scholar

Henle T. Protein-bound advanced glycation endproducts (AGEs) as bioactive amino acid derivatives in foods. Amino Acids 29, 313–22, 2005.Search in Google Scholar

Hellwig M, Auerbach C, Muller N, Samuel P, Kammann S, Beer F, Gunzer F, Henle T. Metabolization of the advanced glycation end product N-ε-carboxymethyllysine (CML) by different probiotic E. coli strains. J Agric Food Chem 67, 1963–1972, 2019.Search in Google Scholar

Hudson BI, Lippman ME. Targeting RAGE signaling in inflammatory disease. Annu Rev Med 69, 349–364, 2018. Hurrle S, Hsu WH. The etiology of oxidative stress in insulin resistance. Biomed J 40, 257–262, 2017.Search in Google Scholar

Inan-Eroglu E, Ayaz A, Buyuktuncer Z. Formation of advanced glycation endproducts in foods during cooking process and underlying mechanisms: a comprehensive review of experimental studies. Nutr Res Rev 33, 77–89, 2020.Search in Google Scholar

Juranek J, Mukherjee K, Kordas B, Zalecki M, Korytko A, Zglejc-Waszak K, Szuszkiewicz J, Banach M. Role of RAGE in the pathogenesis of neurological disorders. Neurosci Bull 38, 1248–1262, 2022.Search in Google Scholar

Katakami N. Mechanism of development of atherosclerosis and cardiovascular disease in diabetes mellitus. J Atheroscler Thromb 25, 27–39, 2018.Search in Google Scholar

Ke LY, Chan HC, Chen CC, Chang CF, Lu PL, Chu CS, Lai WT, Shin SJ, Liu FT, Chen CH. Increased APOE glycosylation plays a key role in the atherogenicity of L5 low-density lipoprotein. FASEB J 34, 9802–9813, 2020.Search in Google Scholar

Kelley N, Jeltema D, Duan Y, He Y. The NLRP3 inflammasome: An overview of mechanisms of activation and regulation. Int J Mol Sci 20, 3328, 2019.Search in Google Scholar

Khalid M, Alkaabi J, Khan MAB, Adem A. Insulin signal transduction perturbations in insulin resistance. Int J Mol Sci 22, 8590, 2021.Search in Google Scholar

Khalid M, Petroianu G, Adem A. Advanced glycation end products and diabetes mellitus: mechanisms and perspectives. Biomolecules 12, 542, 2022.Search in Google Scholar

Khosravi M, Poursaleh A, Ghasempour G, Farhad S, Najafi M. The effects of oxidative stress on the development of atherosclerosis. Biol Chem 400, 711–732, 2019.Search in Google Scholar

Lacatusu CM, Grigorescu ED, Floria M, Onofriescu A, Mihai BM. The Mediterranean diet: from an environment-driven food culture to an emerging medical prescription. Int J Environ Res Public Health 16, 942, 2019.Search in Google Scholar

La Sala L, Prattichizzo F, Ceriello A. The link between diabetes and atherosclerosis. Eur J Prev Cardiol 26, 15–24, 2019.Search in Google Scholar

Lentini P, Zanoli L, Ronco C, Benedetti C, Previti A, Laudadio G, Vienna F, Andrighetto S, Fuso V, Gambaro G. The vascular disease of diabetic kidney disease. Cardiorenal Med 13, 202–210, 2023.Search in Google Scholar

Le Bagge S, Fotheringham AK, Leung SS, Forbes JM. Targeting the receptor for advanced glycation end products (RAGE) in type 1 diabetes. Med Res Rev 40, 1200–1219, 2020.Search in Google Scholar

Li M, Shen M, Lu J, Yang J, Huang Y, Liu L, Fan H, Xie J, Xie M. Maillard reaction harmful products in dairy products: Formation, occurrence, analysis, and mitigation strategies. Food Res Int 151, 110839, 2022.Search in Google Scholar

Liang Z, Chen X, Li L, Li B, Yang Z. The fate of dietary advanced glycation end products in the body: from oral intake to excretion. Crit Rev Food Sci Nutr 60, 3475–3491, 2020.Search in Google Scholar

Lopez-Moreno J, Quintana-Navarro GM, Camargo A, Jimenez-Lucena R, Delgado-Lista J, Marin C, Tinahones FJ, Striker GE, Roche HM, Perez-Martinez P, Lopez-Miranda J, Yubero-Serrano EM. Dietary fat quantity and quality modifies advanced glycation end products metabolism in patients with metabolic syndrome. Mol Nutr Food Res 61, 1601029, 2017.Search in Google Scholar

Lund MN, Ray CA. Control of Maillard reactions in foods: strategies and chemical mechanisms. J Agric Food Chem 65, 4537–4552, 2017.Search in Google Scholar

Luo W, He Y, Ding F, Nie X, Li XL, Song HL, Li GX. Study on the levels of glycosylated lipoprotein in patients with coronary artery atherosclerosis. J Clin Lab Anal 33, e22650, 2019.Search in Google Scholar

Luo Y, Li S, Ho CT. Key aspects of Amadori rearrangement products as future food additives. Molecules 26, 4314, 2021.Search in Google Scholar

Ma J, Li Y, Yang X, Liu K, Zhang X, Zuo X, Ye R, Wang Z, Shi R, Meng Q, Chen X. Signaling pathways in vascular function and hypertension: molecular mechanisms and therapeutic interventions. Signal Transduct Target Ther 8, 168, 2023.Search in Google Scholar

Maillard LC. Action of amino acids on sugars. Formation of melanoidins in a methodical way. Compt Rend 154, 66–68, 1912.Search in Google Scholar

Manig F, Hellwig M, Pietz F, Henle T. Studies about the dietary impact on “free” glycation compounds in human saliva. Foods 11, 2112, 2022.Search in Google Scholar

Munch G, Schicktanz D, Behme A, Gerlach M, Riederer P, Palm D, Schinzel R. Amino acid specificity of glycation and protein-AGE crosslinking reactivities determined with a dipeptide SPOT library. Nat Biotechnol 17, 1006–1010, 1999.Search in Google Scholar

Munoz N, Pedreanez A, Mosquera J. Angiotensin II induces increased myocardial expression of receptor for advanced glycation end products, monocyte/macrophage infiltration and circulating endothelin-1 in rats with experimental diabetes. Can J Diabetes 44, 651–656, 2020.Search in Google Scholar

Neeper M, Schmidt AM, Brett J, Yan SD, Wang F, Pan YC, Elliston K, Stern D, Shaw A. Cloning and expression of a cell surface receptor for advanced glycosylation end products of proteins. J Biol Chem 267, 14998–5004, 1992.Search in Google Scholar

Nowotny K, Jung T, Hohn A, Weber D, Grune T. Advanced glycation end products and oxidative stress in type 2 diabetes mellitus. Biomolecules 5, 194–222, 2015.Search in Google Scholar

Parwani K, Mandal P. Role of advanced glycation end products and insulin resistance in diabetic nephropathy. Arch Physiol Biochem 30, 1–13, 2020.Search in Google Scholar

Patel SH, Carroll CC. Impact of elevated serum advanced glycation end products and exercise on intact and injured murine tendons. Connect Tissue Res 64, 161–174, 2023.Search in Google Scholar

Pedreanez A, Mosquera J, Munoz N, Robalino J, Tene D. Diabetes, heart damage, and angiotensin II. What is the relationship link between them? A minireview. Endocr Regul 56, 55–65, 2022.Search in Google Scholar

Peppa M, Mavroeidi I. Experimental animal studies support the role of dietary advanced glycation end products in health and disease. Nutrients 13, 3467, 2021.Search in Google Scholar

Pinto-Junior DC, Silva KS, Michalani ML, Yonamine CY, Esteves JV, Fabre NT, Thieme K, Catanozi S, Okamoto MM, Seraphim PM, Correa-Giannella ML, Passarelli M, Machado UF. Advanced glycation end products-induced insulin resistance involves repression of skeletal muscle GLUT4 expression. Sci Rep 8, 8109, 2018.Search in Google Scholar

Poulsen MW, Hedegaard RV, Andersen JM, de Courten B, Bugel S, Nielsen J, Skibsted LH, Dragsted LO. Advanced glycation endproducts in food and their effects on health. Food Chem Toxicol 60, 10–37, 2013.Search in Google Scholar

Prestes Fallavena L, Poerner Rodrigues N, Damasceno Ferreira Marczak L, Domeneghini Mercali G. Formation of advanced glycation end products by novel food processing technologies: A review. Food Chem 393, 133338, 2022.Search in Google Scholar

Qing C. The molecular biology in wound healing & non-healing wound. Chin J Traumatol 20, 189–193, 2017.Search in Google Scholar

Raut SK, Khullar M. Oxidative stress in metabolic diseases: current scenario and therapeutic relevance. Mol Cell Biochem 478, 185–196, 2023.Search in Google Scholar

Rheinheimer J, de Souza BM, Cardoso NS, Bauer AC, Crispim D. Current role of the NLRP3 inflammasome on obesity and insulin resistance: A systematic review. Metabolism 74, 1–9, 2017.Search in Google Scholar

Roncero-Ramos I, Delgado-Andrade C, Tessier FJ, Niquet-Leridon C, Strauch C, Monnier VM, Navarro MP. Metabolic transit of N(ε)-carboxymethyl-lysine after consumption of AGEs from bread crust. Food Funct 4, 1032–1039, 2013.Search in Google Scholar

Rowan S, Bejarano E, Taylor A. Mechanistic targeting of advanced glycation end-products in age-related diseases. Biochim Biophys Acta Mol Basis Dis 1864, 3631–3643, 2018.Search in Google Scholar

Ruiz HH, Ramasamy R, Schmidt AM. Advanced glycation end products: building on the concept of the “Common Soil” in metabolic disease. Endocrinology 161, bqz006, 2020.Search in Google Scholar

Sahajpal NS, Goel RK, Chaubey A, Aurora R, Jain SK. Pathological perturbations in diabetic retinopathy: hyperglycemia, AGEs, oxidative stress and inflammatory pathways. Curr Protein Pept Sci 20, 92–110, 2019.Search in Google Scholar

Sahi AK, Verma P, Varshney N, Gundu S, Mahto SK. Revisiting methodologies for in vitro preparations of advanced glycation end products. Appl Biochem Biotechnol 194, 2831–2855, 2022.Search in Google Scholar

Salazar-Villanea S, Butre CI, Wierenga PA, Bruininx EMAM, Gruppen H, Hendriks WH, van der Poel AFB. Apparent ileal digestibility of Maillard reaction products in growing pigs. PLoS One 13, e0199499, 2018.Search in Google Scholar

Salazar J, Navarro C, Ortega A, Nava M, Morillo D, Torres W, Hernandez M, Cabrera M, Angarita L, Ortiz R, Chacín M, D’Marco L, Bermudez V. Advanced glycation end products: new clinical and molecular perspectives. Int J Environ Res Public Health 18, 7236, 2021.Search in Google Scholar

Sant S, Wang D, Agarwal R, Dillender S, Ferrell N. Glycation alters the mechanical behavior of kidney extracellular matrix. Matrix Biol Plus 8, 100035, 2020.Search in Google Scholar

Shaikh-Kader A, Houreld NN, Rajendran NK, Abrahamse H. The link between advanced glycation end products and apoptosis in delayed wound healing. Cell Biochem Funct 37, 432–442, 2019.Search in Google Scholar

Shen CY, Lu CH, Wu CH, Li KJ, Kuo YM, Hsieh SC, Yu CL. The development of Maillard reaction, and advanced glycation end product (AGE)-receptor for AGE (RAGE) signaling inhibitors as novel therapeutic strategies for patients with AGE-related diseases. Molecules 25, 5591, 2020.Search in Google Scholar

Scheijen J, Clevers E, Engelen L, Dagnelie PC, Brouns F, Stehouwer CDA, Schalkwijk CG. Analysis of advanced glycation endproducts in selected food items by ultra-performance liquid chromatography tandem mass spectrometry: Presentation of a dietary AGE database. Food Chem 190, 1145–1150, 2016.Search in Google Scholar

Schmidt AM, Stern DM. Receptor for age (RAGE) is a gene within the major histocompatibility class III region: implications for host response mechanisms in homeostasis and chronic disease. Front Biosci 6, D1151–D1160, 2001.Search in Google Scholar

Son S, Hwang I, Han SH, Shin JS, Shin OS, Yu JW. Advanced glycation end products impair NLRP3 inflammasome-mediated innate immune responses in macrophages. J Biol Chem 292, 20437–20448, 2017.Search in Google Scholar

Steenbeke M, De Bruyne S, De Buyzere M, Lapauw B, Speeckaert R, Petrovic M, Delanghe JR, Speeckaert MM. The role of soluble receptor for advanced glycation end-products (sRAGE) in the general population and patients with diabetes mellitus with a focus on renal function and overall outcome. Crit Rev Clin Lab Sci 58, 113–130, 2021.Search in Google Scholar

Stefano GB, Challenger S, Kream RM. Hyperglycemia-associated alterations in cellular signaling and dysregulated mitochondrial bioenergetics in human metabolic disorders. Eur J Nutr 55, 2339–2345, 2016.Search in Google Scholar

Stolarczyk A, Sarzynska S, Gondek A, Cudnoch-Jedrzejewska A. Influence of diabetes on tissue healing in orthopaedic injuries. Clin Exp Pharmacol Physiol 45, 619–627, 2018.Search in Google Scholar

Svensson RB, Smith ST, Moyer PJ, Magnusson SP. Effects of maturation and advanced glycation on tensile mechanics of collagen fibrils from rat tail and Achilles tendons. Acta Biomater 70, 270–280, 2018.Search in Google Scholar

Teissier T, Boulanger E. The receptor for advanced glycation end-products (RAGE) is an important pattern recognition receptor (PRR) for inflammaging. Biogerontology 20, 279–301, 2019.Search in Google Scholar

Tristan Asensi M, Napoletano A, Sofi F, Dinu M. Low-grade inflammation and ultra-processed foods consumption: A review. Nutrients 15, 1546, 2023.Search in Google Scholar

Troise AD, Fogliano V, Vitaglione P, Berton-Carabin CC. Interrelated routes between the Maillard reaction and lipid oxidation in emulsion systems. J Agric Food Chem 68, 12107–12115, 2020.Search in Google Scholar

Twarda-Clapa A, Olczak A, Bialkowska AM, Koziolkiewicz M. Advanced glycation end-products (AGEs): formation, chemistry, classification, receptors, and diseases related to AGEs. Cells 11, 1312, 2022.Search in Google Scholar

Urquiaga I, Echeverria G, Dussaillant C, Rigotti A. Origen, componentes y posibles mecanismos de accion de la dieta mediterranea [Origin, components and mechanisms of action of the Mediterranean diet]. Rev Med Chil 145, 85–95, 2017.Search in Google Scholar

Van der Lugt T, Opperhuizen A, Bast A, Vrolijk MF. Dietary advanced glycation endproducts and the gastrointestinal tract. Nutrients 12, 2814, 2020.Search in Google Scholar

Van de Vyver M. Immunology of chronic low-grade inflammation: relationship with metabolic function. J Endocrinol 257, e220271, 2023.Search in Google Scholar

Van Putte L, De Schrijver S, Moortgat P. The effects of advanced glycation end products (AGEs) on dermal wound healing and scar formation: a systematic review. Scars Burn Heal 2, 2059513116676828, 2016.Search in Google Scholar

Vasishta S, Umakanth S, Adiga P, Joshi MB. Extrinsic and intrinsic factors influencing metabolic memory in type 2 diabetes. Vascul Pharmacol 142, 106933, 2022.Search in Google Scholar

Vistoli G, De Maddis D, Cipak A, Zarkovic N, Carini M, Aldini G. Advanced glycoxidation and lipoxidation end products (AGEs and ALEs): an overview of their mechanisms of formation. Free Radic Res 47, 3–27, 2013. Search in Google Scholar

Wang C, Lu Y, Huang Q, Zheng T, Sang S, Lv L. Levels and formation of α-dicarbonyl compounds in beverages and the preventive effects of flavonoids. J Food Sci Technol 54, 2030–2040, 2017a.Search in Google Scholar

Wang Q, Zhu G, Cao X, Dong J, Song F, Niu Y. Blocking AGE-RAGE signaling improved functional disorders of macrophages in diabetic wound. J Diabetes Res 2017, 1428537, 2017b.Search in Google Scholar

Wang M, Hng TM. HbA1c: More than just a number. Aust J Gen Pract 50, 628–632, 2021.Search in Google Scholar

Wu XQ, Zhang DD, Wang YN, Tan YQ, Yu XY, Zhao YY. AGE/RAGE in diabetic kidney disease and ageing kidney. Free Radic Biol Med 171, 260–271, 2021.Search in Google Scholar

Xing H, Lee H, Luo L, Kyriakides TR. Extracellular matrix-derived biomaterials in engineering cell function. Biotechnol Adv 42, 107421, 2020.Search in Google Scholar

Yan S, Wu L, Xue X. α-Dicarbonyl compounds in food products: Comprehensively understanding their occurrence, analysis, and control. Compr Rev Food Sci Food Saf 22, 1387–1417, 2023.Search in Google Scholar

Yu W, Tao M, Zhao Y, Hu X, Wang M. 4’-Methoxyresveratrol alleviated AGE-induced inflammation via RAGE-mediated NF-κB and NLRP3 inflammasome pathway. Molecules 23, 1447, 2018.Search in Google Scholar

Yu W, Fan L, Wang M, Cao B, Hu X. Pterostilbene improves insulin resistance caused by advanced glycation end products (AGEs) in hepatocytes and mice. Mol Nutr Food Res 65, e2100321, 2021.Search in Google Scholar

Yue Q, Song Y, Liu Z, Zhang L, Yang L, Li J. Receptor for advanced glycation end products (RAGE): A pivotal hub in immune diseases. Molecules 27, 4922, 2022.Search in Google Scholar

Zeng C, Li Y, Ma J, Niu L, Tay FR. Clinical/translational aspects of advanced glycation end-products. Trends Endocrinol Metab 30, 959–973, 2019.Search in Google Scholar

Zhao Y, Luo C, Chen J, Sun Y, Pu D, Lv A, Zhu S, Wu J, Wang M, Zhou J, Liao Z, Zhao K, Xiao Q. High glucose-induced complement component 3 up-regulation via RAGE-p38MAPK-NF-κB signalling in astrocytes: In vivo and in vitro studies. J Cell Mol Med 22, 6087–6098, 2018.Search in Google Scholar

Zhang Q, Wang Y, Fu L. Dietary advanced glycation end-products: Perspectives linking food processing with health implications. Compr Rev Food Sci Food Saf 19, 2559–2587, 2020.Search in Google Scholar