<abstract xmlns="http://www.w3.org/1999/xhtml"><p> The smoke of cigarettes with high base content was examined for primary and secondary bases. As 4'-nitro-azobenzenecarboxamides- (4) (NABSA) the bases were separated by column and thin-layer chromatography and identified by melting points, R<sub>F</sub>-values, IR-spectra, retention times, mass-spectra, and elemental analyses. 27 primary and secondary bases were isolated and 24 of them identified. For the first time n-propylamine, n-butylamine, iso-butylamine, iso-pentylamine, b-phenethylamine, methyl ethylamine, diethylamine, methyl-b-phenethylamine, 1,2,5,6-tetrahydropyridine, aniline, 3-methylaminopyridine, and dihydrometanicotine were detected in cigarette smoke. Earlier results about the presence of pyrrolidine, piperidine, and 2-methylpyrrolidine in smoke could be confirmed. Presumably methyl-n-butylamine and methyl-iso-butylamine are to be found in tobacco smoke. One further amine was not identified.</p></abstract>

The smoke of cigarettes with high base content was examined for primary and secondary bases. As 4'-nitro-azobenzenecarboxamides- (4) (NABSA) the bases were separated by column and thin-layer chromatography and identified by melting points, RF-values, IR-spectra, retention times, mass-spectra, and elemental analyses. 27 primary and secondary bases were isolated and 24 of them identified. For the first time n-propylamine, n-butylamine, iso-butylamine, iso-pentylamine, b-phenethylamine, methyl ethylamine, diethylamine, methyl-b-phenethylamine, 1,2,5,6-tetrahydropyridine, aniline, 3-methylaminopyridine, and dihydrometanicotine were detected in cigarette smoke. Earlier results about the presence of pyrrolidine, piperidine, and 2-methylpyrrolidine in smoke could be confirmed. Presumably methyl-n-butylamine and methyl-iso-butylamine are to be found in tobacco smoke. One further amine was not identified.

Examination of Volatile Bases in Cigarette Smoke / Untersuchung der Flüchtigen Basen des Tabakrauches

Forschungslaboratorium H. F. & Ph. F. Reemtsma, Hamburg, Germany

Contributions to Tobacco & Nicotine Research

This article is distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

The smoke of cigarettes with high base content was examined for primary and secondary bases. As 4'-nitro-azobenzenecarboxamides- (4) (NABSA) the bases were...

Examination of Volatile Bases in Cigarette Smoke / Untersuchung der Flüchtigen Basen des Tabakrauches

Publié en ligne: 13 juin 2014

Pages: 563 - 569

DOI: https://doi.org/10.2478/cttr-2013-0154

© Beiträge zur Tabakforschung International

This article is distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.