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Walnut (Juglans regia L.) is the most widespread walnut in the world. All parts of the plant are important: bark, leaves, dried and green peel of the fruit, septum, core. The benefits of walnuts are due to the presence of phytochemicals such as flavonoids, carotenoids, alkaloids, polyphenols, etc. In addition to the many benefits that walnut has on our health (antibacterial, antioxidant), it also has important phytosanitary and insecticidal properties. Walnuts can be used because of their plant-friendly properties in the form of biopesticides that are safe and can be a viable, inexpensive and cleaner alternative to synthetic products that can be harmful to the environment. This review paper seeks to bring to the fore the available literature on Juglans regia directed on the properties, antifungals and insecticides with action on plants and antibacterials with action on the human body, as well as mathematical models regarding the multiplication of microorganisms.