<abstract xmlns="http://www.w3.org/1999/xhtml">
<p>Acetaminophen solubility in the glycerol and ethanol mixture was determined by a simple shake-flask technique at different temperatures and fitted to some mathematical models and the models’ accuracy was investigated by the computation of the mean relative deviations. The densities of acetaminophen saturated mixtures were also studied by the Jouyban-Acree model. Moreover, the Gibbs and van’t Hoff equations were utilized to compute apparent thermodynamic parameters of the acetaminophen dissolving. </p>
</abstract>

Acetaminophen solubility in the glycerol and ethanol mixture was determined by a simple shake-flask technique at different temperatures and fitted to some mathematical models and the models’ accuracy was investigated by the computation of the mean relative deviations. The densities of acetaminophen saturated mixtures were also studied by the Jouyban-Acree model. Moreover, the Gibbs and van’t Hoff equations were utilized to compute apparent thermodynamic parameters of the acetaminophen dissolving.

Solubility of acetaminophen in the ethanol and glycerol mixtures at different temperatures

Pharmaceutical Analysis Research Center and Faculty of Pharmacy

Student Research Committee, Faculty of Pharmacy

Shahid Beheshti University of Medical Sciences

Ovidius University Annals of Chemistry

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Acetaminophen solubility in the glycerol and ethanol mixture was determined by a simple shake-flask technique at different temperatures and fitted to some...

Solubility of acetaminophen in the ethanol and glycerol mixtures at different temperatures

Publié en ligne: 13 sept. 2023

Pages: 99 - 103

Reçu: 28 mars 2023

Accepté: 14 août 2023

DOI: https://doi.org/10.2478/auoc-2023-0013

Mots clés
acetaminophen, solubility, glycerol, ethanol, binary mixture, cosolvency models

© 2023 Nafiseh Gholizadeh et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Solubility of acetaminophen in the ethanol and glycerol mixtures at different temperatures

Publié en ligne: 13 sept. 2023

Pages: 99 - 103

Reçu: 28 mars 2023

Accepté: 14 août 2023

DOI: https://doi.org/10.2478/auoc-2023-0013

Mots clésacetaminophen, solubility, glycerol, ethanol, binary mixture, cosolvency models

© 2023 Nafiseh Gholizadeh et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Mots clés
acetaminophen, solubility, glycerol, ethanol, binary mixture, cosolvency models