<abstract xmlns="http://www.w3.org/1999/xhtml">Kinetics of oxidation of Lysine (Lys) and mechanisms by μ-peroxo <italic>bis</italic>[<italic>bis</italic>(ethylenediamine)succinimidato-dicobalt(III)]dinitratedihydrate; [LCo(μ-O2)CoL](NO3)2.2H2O (L = suc(en)2), hereafter the complex, was investigated at 420 nm wavelength of maximum absorption of the complex under the conditions hydrogen ions concentration = 1.8 × 10−2 mol dm−3, temperature = 24 ± 1 °C, [LCo(μ-O2)CoL2+] = 1.4 × 10−4 mol dm−3 and ionic strength = 0.5 mol dm−3. First order in [LCo(μ-O2)CoL2+] and [Lys] were obtained but inverse first order in [H+]. The proposed overall rate equation is as shown:<disp-formula><alternatives><graphic xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="graphic/j_ast-2018-0006_eq_001.png"></graphic><math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mrow><mi>Rate</mi><mo>=</mo><mo>(</mo><mfrac><mrow><msub><mi>k</mi><mn>1</mn></msub></mrow><mrow><msub><mi>k</mi><mn>2</mn></msub></mrow></mfrac><mo>+</mo><mfrac><mrow><msub><mi>K</mi><mn>1</mn></msub><msub><mi>k</mi><mn>3</mn></msub></mrow><mrow><msub><mi>k</mi><mn>4</mn></msub></mrow></mfrac><mfrac><mn>1</mn><mrow><mo>[</mo><msup><mi>H</mi><mo>+</mo></msup><mo>]</mo></mrow></mfrac><mo>)</mo><mo>[</mo><mi>LCo</mi><mo>(</mo><mo>μ</mo><msub><mi>O</mi><mn>2</mn></msub><mo>)</mo><msup><mi>CoL</mi><mrow><mn>2</mn><mo>+</mo></mrow></msup><mo>]</mo><mo>[</mo><mi>Lys</mi><mo>]</mo></mrow></math><tex-math>$$Rate = ({{k_1 } \over {k_2 }} + {{K_1 k_3 } \over {k_4 }}{1 \over {[H^ + ]}})[LCo(\mu O_2 )CoL^{2 + } ][Lys]$$</tex-math></alternatives></disp-formula>Rate of the reaction decreases when hydrogen ions concentration increase and exhibited converse effect with increase in concentration of ionic strength from 0.1 – 1.3 mol dm−3. Added cations and anions affected the reaction rate and the Michaelis-Menten plot passed through the origin indicating no absence of intermediate complex in the electron transfer processes. Putting all the results obtained together, the most probable reaction mechanism is in favour of outer-sphere and an appropriate rate law is established using steady state approximation.</abstract>

Kinetics of oxidation of Lysine (Lys) and mechanisms by μ-peroxo bis[bis(ethylenediamine)succinimidato-dicobalt(III)]dinitratedihydrate; [LCo(μ-O2)CoL](NO3)2.2H2O (L = suc(en)2), hereafter the complex, was investigated at 420 nm wavelength of maximum absorption of the complex under the conditions hydrogen ions concentration = 1.8 × 10−2 mol dm−3, temperature = 24 ± 1 °C, [LCo(μ-O2)CoL2+] = 1.4 × 10−4 mol dm−3 and ionic strength = 0.5 mol dm−3. First order in [LCo(μ-O2)CoL2+] and [Lys] were obtained but inverse first order in [H+]. The proposed overall rate equation is as shown:Rate=(k1k2+K1k3k41[H+])[LCo(μO2)CoL2+][Lys]$$Rate = ({{k_1 } \over {k_2 }} + {{K_1 k_3 } \over {k_4 }}{1 \over {[H^ + ]}})[LCo(\mu O_2 )CoL^{2 + } ][Lys]$$Rate of the reaction decreases when hydrogen ions concentration increase and exhibited converse effect with increase in concentration of ionic strength from 0.1 – 1.3 mol dm−3. Added cations and anions affected the reaction rate and the Michaelis-Menten plot passed through the origin indicating no absence of intermediate complex in the electron transfer processes. Putting all the results obtained together, the most probable reaction mechanism is in favour of outer-sphere and an appropriate rate law is established using steady state approximation.

The Kinetics of the Oxidation of Lysine by μ-Peroxo-Bridged Binuclear Cobalt (III) Complex of Succinimide in Aqueous Hydrochloric Acid Medium

Department of Chemical Science, Yaba College of Technology

Department of Chemistry, Federal College of Education

Annals of Science and Technology

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Kinetics of oxidation of Lysine (Lys) and mechanisms by μ-peroxo bis[bis(ethylenediamine)succinimidato-dicobalt(III)]dinitratedihydrate;...

The Kinetics of the Oxidation of Lysine by μ-Peroxo-Bridged Binuclear Cobalt (III) Complex of Succinimide in Aqueous Hydrochloric Acid Medium

Publié en ligne: 16 avr. 2018

Pages: 37 - 43

Reçu: 22 févr. 2017

Accepté: 17 juil. 2017

DOI: https://doi.org/10.2478/ast-2018-0006

Mots clés
Amino acid, Redox reaction, Mechanism, Peroxo-bridge Complex of Succinimide

© 2018 Ahmed Adetoro et al., published by De Gruyter Open

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

The Kinetics of the Oxidation of Lysine by μ-Peroxo-Bridged Binuclear Cobalt (III) Complex of Succinimide in Aqueous Hydrochloric Acid Medium

Publié en ligne: 16 avr. 2018

Pages: 37 - 43

Reçu: 22 févr. 2017

Accepté: 17 juil. 2017

DOI: https://doi.org/10.2478/ast-2018-0006

Mots clésAmino acid, Redox reaction, Mechanism, Peroxo-bridge Complex of Succinimide

© 2018 Ahmed Adetoro et al., published by De Gruyter Open

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Mots clés
Amino acid, Redox reaction, Mechanism, Peroxo-bridge Complex of Succinimide