<abstract xmlns="http://www.w3.org/1999/xhtml">
<p>This study’s goal was to identify the haemostatic profile of COVID-19 patients and their relationships to disease severity and death rates. 163 COVID-19 patients were enrolled in the research, and their diagnoses were made using PCR, common symptoms, and radiological findings (CT). Patients that were hospitalized to Ali Boushaba Public Hospitalier Khenchela’s Infectology Service in 2020. Data was gathered between January 1 and June 30, 2021. In the population that was counted, patients with COVID-19 have an average age of 61.44 + 15.4 years. The gender ratio of males to women was in the range of 0.98, therefore there was no discernible male predominance. 20% of the oxygen was desaturated, and 38.6% and 6.8% of patients had significant or serious lung disease, respectively. 16.4% mortality was seen in these individuals. These individuals had a wide spectrum of biochemical anomalies, including hyperglycaemia, which had an average value of 1.94+1.22 g/L. An increase in the mean values of CRP (68.35+58.87 mg/l) was noted. About the haemostatic profile we recorded an increase in the level of D-dimer (730.49+674.87 ng/l), a decrease in prothrombin time (55.54+36.24%). The highest D-dimer value (946.40+ 568.02 ng/l) was recorded in patients with critical parenchymal involvement (≥ 75%), and a significant correlation between the D-dimer value and parenchymal involvement was noted. Furthermore, statistically the relationship of haemostatic profile with COVID-19’s severity and with clinical outcome was insignificant.  </p>
</abstract>

This study’s goal was to identify the haemostatic profile of COVID-19 patients and their relationships to disease severity and death rates. 163 COVID-19 patients were enrolled in the research, and their diagnoses were made using PCR, common symptoms, and radiological findings (CT). Patients that were hospitalized to Ali Boushaba Public Hospitalier Khenchela’s Infectology Service in 2020. Data was gathered between January 1 and June 30, 2021. In the population that was counted, patients with COVID-19 have an average age of 61.44 + 15.4 years. The gender ratio of males to women was in the range of 0.98, therefore there was no discernible male predominance. 20% of the oxygen was desaturated, and 38.6% and 6.8% of patients had significant or serious lung disease, respectively. 16.4% mortality was seen in these individuals. These individuals had a wide spectrum of biochemical anomalies, including hyperglycaemia, which had an average value of 1.94+1.22 g/L. An increase in the mean values of CRP (68.35+58.87 mg/l) was noted. About the haemostatic profile we recorded an increase in the level of D-dimer (730.49+674.87 ng/l), a decrease in prothrombin time (55.54+36.24%). The highest D-dimer value (946.40+ 568.02 ng/l) was recorded in patients with critical parenchymal involvement (≥ 75%), and a significant correlation between the D-dimer value and parenchymal involvement was noted. Furthermore, statistically the relationship of haemostatic profile with COVID-19’s severity and with clinical outcome was insignificant.

The Haemostatic Profile in COVID-19 Patients

Laboratory of Pharmacology and Toxicology

Laboratory of Cellular and Molecular Biology

Department of Biochemistry and Biological Cellular and Molecular

Advanced Research in Life Sciences

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

{"article-title":"The Haemostatic Profile in COVID-19 Patients"}

This study’s goal was to identify the haemostatic profile of COVID-19 patients and their relationships to disease severity and death rates. 163 COVID-19...

The Haemostatic Profile in COVID-19 Patients

Publié en ligne: 13 sept. 2023

Pages: 93 - 99

Reçu: 01 févr. 2023

Accepté: 01 août 2023

DOI: https://doi.org/10.2478/arls-2023-0011

Mots clés
Haemostatic profile, COVID-19, D-dimer, Prothrombin, Platelet count

© 2023 Nousseiba Abed et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

The Haemostatic Profile in COVID-19 Patients

Publié en ligne: 13 sept. 2023

Pages: 93 - 99

Reçu: 01 févr. 2023

Accepté: 01 août 2023

DOI: https://doi.org/10.2478/arls-2023-0011

Mots clésHaemostatic profile, COVID-19, D-dimer, Prothrombin, Platelet count

© 2023 Nousseiba Abed et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Mots clés
Haemostatic profile, COVID-19, D-dimer, Prothrombin, Platelet count