<abstract xmlns="http://www.w3.org/1999/xhtml">

<p>Chemical compounds used to prevent and control fish disease often cause environmental hazards; thus, alternative approaches as new and effective strategies are needed. The current investigation was performed with the aim of exploring the effects of dietary Moldavian balm (MB, Dracocephalum moldavica L.) on the growth, immune parameters, and antioxidant status of common carp (Cyprinus carpio). Fish (n=300, w= 3.80±0.02 g) in four groups in triplicates were supplemented with 0%, 0.5%, 1%, and 2% MB. After 42 days, it was found that feed supplements increased final weight (FW), weight gain (WG), and specific growth rate (SGR) and decreased the food conversion ratio (FCR) (P &lt; 0.05). In addition, fish supplemented with 2% MB significantly showed higher serum total protein (TP), alternative complement pathway (ACH50), and glutathione peroxidase (GPx) (P &lt; 0.05). The 0.5% MB-supplemented fish represented higher levels of LYZ, alkaline phosphatase (ALP), total Ig, and ACH50 in their skin mucus in comparison with the unsupplemented fish (P &lt; 0.05). The results also indicated that 2% MB resulted in a significantly higher expression level of intestinal tumor necrosis factor (TNF- α) (P &lt; 0.05); however, the level of LYZ, interleukin-1β (IL-1β), and TLRs decreased in supplemented fish. CAT and SOD expressions were increased in 0.5% MB supplement. In conclusion, MB could be recommended as an efficient feed additive to boost common carp’s growth, immunity, and health status.</p>
</abstract>

Chemical compounds used to prevent and control fish disease often cause environmental hazards; thus, alternative approaches as new and effective strategies are needed. The current investigation was performed with the aim of exploring the effects of dietary Moldavian balm (MB, Dracocephalum moldavica L.) on the growth, immune parameters, and antioxidant status of common carp (Cyprinus carpio). Fish (n=300, w= 3.80±0.02 g) in four groups in triplicates were supplemented with 0%, 0.5%, 1%, and 2% MB. After 42 days, it was found that feed supplements increased final weight (FW), weight gain (WG), and specific growth rate (SGR) and decreased the food conversion ratio (FCR) (P < 0.05). In addition, fish supplemented with 2% MB significantly showed higher serum total protein (TP), alternative complement pathway (ACH50), and glutathione peroxidase (GPx) (P < 0.05). The 0.5% MB-supplemented fish represented higher levels of LYZ, alkaline phosphatase (ALP), total Ig, and ACH50 in their skin mucus in comparison with the unsupplemented fish (P < 0.05). The results also indicated that 2% MB resulted in a significantly higher expression level of intestinal tumor necrosis factor (TNF- α) (P < 0.05); however, the level of LYZ, interleukin-1β (IL-1β), and TLRs decreased in supplemented fish. CAT and SOD expressions were increased in 0.5% MB supplement. In conclusion, MB could be recommended as an efficient feed additive to boost common carp’s growth, immunity, and health status.

Effect of dietary Moldavian balm (<italic>Dracocephalum moldavica</italic> L.) on growth performance, antioxidant status, immune response, and gene expression of common carp (<italic>Cyprinus carpio</italic>)

Department of Fisheries, Faculty of Fisheries and Environmental Sciences

Gorgan University of Agricultural Sciences and Natural Resources

Department of Animal Science, Chaharmahal and Bakhtiari Agricultural and Natural Resources Research and Education Center

Department of Nutritional Sciences, School of Health

Department of Fisheries Science, College of Marine Science

Peoples’ Friendship University of Russia (RUDN University)

Department of Animal and Aquatic Sciences, Faculty of Agriculture

Annals of Animal Science

This work is licensed under the Creative Commons Attribution 4.0 International License.

Effect of dietary Moldavian balm ( L.) on growth performance, antioxidant status, immune response, and gene expression of common carp ()

Chemical compounds used to prevent and control fish disease often cause environmental hazards; thus, alternative approaches as new and effective strategies are...

Effect of dietary Moldavian balm (Dracocephalum moldavica L.) on growth performance, antioxidant status, immune response, and gene expression of common carp (Cyprinus carpio)

Publié en ligne: 24 avr. 2024

Pages: -

Reçu: 19 juin 2023

Accepté: 25 mars 2024

DOI: https://doi.org/10.2478/aoas-2024-0042

Mots clés
fish immunity, herbal immunostimulants, immune-related genes

© 2024 Seyed Hossein Hoseinifar et al., published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.

Effect of dietary Moldavian balm (Dracocephalum moldavica L.) on growth performance, antioxidant status, immune response, and gene expression of common carp (Cyprinus carpio)

Publié en ligne: 24 avr. 2024

Pages: -

Reçu: 19 juin 2023

Accepté: 25 mars 2024

DOI: https://doi.org/10.2478/aoas-2024-0042

Mots clésfish immunity, herbal immunostimulants, immune-related genes

© 2024 Seyed Hossein Hoseinifar et al., published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.

Mots clés
fish immunity, herbal immunostimulants, immune-related genes