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Does Methanolic Leaf Extract of Cassia tora Possess Hepatoprotective Properties in Paracetamol-Induced Liver Damage in Rats?

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09 sept. 2025
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Asrani SK, Devarbhavi H, Eaton J, Kamath PS. Burden of liver diseases in the world. Journal of Hepatology, 2019, 70(1):151-171. Search in Google Scholar

Valkov I, Ivanova R, Marinova C, et al. A comparative analysis of serum lipids in patients with chronic hepatitis C, non alcoholic fatty liver disease and healthy controls. Acta Medica Bulgarica, 2017, 44: 5-10. Search in Google Scholar

Chancharoenthana W, Leelahavanichkul A. Acute kidney injury spectrum in patients with chronic liver disease: Where do we stand? World Journal of Gastroenterology, 2019, 25(28):3684-3703. Search in Google Scholar

Starvrakeva K, Popova M, Esad M, et al. Drug-induced liver toxicity. Acta Medica Bulgarica, 2024, 51(4): 77-85. Search in Google Scholar

Zhang J, Lin S, Jiang D, et al. Chronic hepatitis B and non-alcoholic fatty liver disease: Conspirators or competitors? Liver International, 2020, 40(3):496-508. Search in Google Scholar

Buzzetti E, Kalafateli M, Thorburn D, et al 2017. Pharmacological interventions for alcoholic liver disease (alcohol-related liver disease): an attempted network meta-analysis. Cochrane Database Systemic Review, 3(3):11646-11653. Search in Google Scholar

Okaiyeto K, Oguntibeju OO. African Herbal Medicines: Adverse Effects and Cytotoxic Potentials with Different Therapeutic Applications. International Journal of Environmental Research and Public Health, 2021, 18(11):5988. Search in Google Scholar

Tsanova-Savova S, Velikov S, Paneva S, et al. Comparative Evaluation of the content of antioxidant polyphenolic compounds in selected Bulgarian medicinal plants. Acta Medica Bulgarica, 2022, 49(1): 26-34. Search in Google Scholar

Kpodar MS, Karou SD, Katawa G, et al. An ethnobotanical study of plants used to treat liver diseases in the Maritime region of Togo. Journal of Ethnopharmacology, 2016, 181:263-273. Search in Google Scholar

Ali M, Khan T, Fatima K, et al. Selected hepatoprotective herbal medicines: Evidence from ethnomedicinal applications, animal models, and possible mechanism of actions. Phytotherapy Research, 2018, 32(2):199-215. Search in Google Scholar

Izzo AA, Hoon-Kim S, Radhakrishnan R, Williamson EM. A critical approach to evaluating clinical enjcacy, adverse events and drug interactions of herbal remedies. Phytotherapy Research, 2016, 30(5):691-700. Search in Google Scholar

Latief U, Ahmad R. Herbal remedies for liver fibrosis: A review on the mode of action of fifty herbs. Journal of Traditional and Complementary Medicine, 2017, 8(3):352-360. Search in Google Scholar

Ali M, Khan T, Fatima K, et al. Selected hepatoprotective herbal medicines: Evidence from ethnomedicinal applications, animal models, and possible mechanism of actions. Phytotherapy Research, 2018, 32(2):199-215. Search in Google Scholar

Pawar HA, D’mello PM. Cassia tora Linn.: an overview. International Journal of Pharmaceutical Science and Research, 2011, 2(9): 2286-2291. Search in Google Scholar

Kumar RS, Narasingappa RB, Joshi CG, et al. Evaluation of Cassia tora Linn. against oxidative stress-induced DNA and cell membrane damage. Journal of Pharmacology and Bioallied Sciences, 2017, 9(1):33-43. Search in Google Scholar

Harborne JB. Phytochemical Methods. A Guide to Modern Technology of Plant Analysis, 3rd Edn. Chapman and Hall, New York, 1998. pp. 88-185. Search in Google Scholar

Lorke D. A new approach to practical acute toxicity testing. Archives of Toxicology, 19893, 35: 275-287. Search in Google Scholar

Reitman S, Frankel S. A colorimetric method for the determination of serum glutamate oxaloacetate and pyruvate transaminase. American Journal of Clinical Pathology. 1957, 28: 56-63. Search in Google Scholar

Englehardt VA. Measurement of alkaline phosphatase. Aerztl-Labour 1970, 16:42 Search in Google Scholar

Jendrassik L, Grof P. In Vitro determination of total and direct bilirubin. Biochemica, 1938, 297: 81-9 Search in Google Scholar

Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. Protein measurement with the Folin phenol reagent. Journal of Biology and Chemistry, 1951, 193: 265-275. Search in Google Scholar

Henry JB. Clinical Diagnosis and Management.17th ed, W.B. Saunder Co., Philadelphia, p. 157 (1984) Search in Google Scholar

Fawcett JK, Scott JE. A rapid and precise method for the determination of urea. Journal of Clinical Pathology, 1960, 13, 156-159. Search in Google Scholar

Trinder P. A rapid method for the determination of sodium in serum. Analyst, 1951;76: 596-599. Search in Google Scholar

Skeggs LT, Hochstrasser HC. Colorimetric determination of chloride. Clinical Chemistry, 1964;10: 918-925. Search in Google Scholar

Exner R, Wessner B, Manhart N, Roth, E. Therapeutic potential of glutathione.Wien Klin Wochenschr, 2000;112: 610-616. Search in Google Scholar

Arthur JR, Boyne R. Superoxide dismutase and glutathione peroxidase activities in neutrophil from selenium deficient and copper deficient cattle.Life Sciences, 1985, 36: 1569-1575. Search in Google Scholar

Aebi H. Catalase Invitro. Methods Enzymol. 1984;105: 121-126. Search in Google Scholar

Wallin B, Rosengren B, Shertzer HG. Camejo G. Lipoprotein oxidation and measurement of TBARS formation in single microlitre plate; its use for evaluation of antioxidants. Analytical Biochemistry, 1993, 208: 10-15. Search in Google Scholar

Cholendra A, Vijayaraghavan R, Babu Y, et al. Acute toxicity studies of Cassia tora leaf powder International Journal of Pharmacology Research, 2014, (4): 176-181. Search in Google Scholar

Mulroy E, Baschieri F, Magrinelli F, et al. Movement disorders and liver disease. Movement Disorders Clinical Practice, 2021, 8(6): 828-842 Search in Google Scholar

Rotundo L, Pyrsopoulos N. Liver injury induced by paracetamol and challenges associated with intentional and unintentional use. World Journal of Hepatology, 2020, 12(4):125-136. Search in Google Scholar

Shehu S, Abubakar AS, Ahmed H. Evaluation of hepatotoxic effects of leaves extract of Cassia italica (Mill.) Lam. ex F.W. Ander (Leguminosae) in albino rats. Journal of Applied Sciences and Environmental Management, 2018, 22(9):1539-1542. Search in Google Scholar

Tiwari P, Kumar K, Panik R, et al. Hepatoprotective effects of Cassia tora whole plant. International Journal of Pharmacy and Technology, 2011, 3(2): 2798-2806. Search in Google Scholar

Chen S, Li S, Zhu K, et al. Antitumor activities of Juemingzi (Cassia toraL.) on Balb/c sarcoma 180injected mice. Oncology Letters 2014, 7: 250-254. Search in Google Scholar

Ye H, Luo J, Hu D, et al. Total Flavonoids of Crocus sativus petals release tert-butyl hydroperoxide-induced oxidative stress in BRL-3A cells. Oxidative Medicine and Cellular Longevity, 2021:5453047. Search in Google Scholar

Yamada S, Inaba M. Potassium metabolism and management in patients with CKD. Nutrients, 2021, 13(6):1751. Search in Google Scholar

Yohanna ER, Yakubu OE. Sub-acute nephrotoxicity of ethanol fraction of Senna tora on Wistar albino rats. GSC Advanced Research and Reviews, 2023, 16(02): 145–157 Search in Google Scholar

Park SI, Yun HC, Kang SW, et al. Effect of the seed of Cassia tora extract in the prevention of remote renal reperfusion injury. Transplantation Proceedings, 2019, 51(8):2833-2837. Search in Google Scholar

Baker LB. Physiology of sweat gland function: The roles of sweating and sweat composition in human health. Temperature (Austin), 2019, 6(3):211-259. Search in Google Scholar

Den Bakker E, Gemke RJBJ, Bökenkamp A. Endogenous markers for kidney function in children: a review. Crit Rev Clin Lab Sci. 2018 May;55(3):163-183. Search in Google Scholar

Treacy O, Brown NN, Dimeski G. Biochemical evaluation of kidney disease. Transl Androl Urol. 2019 May;8(Suppl 2):S214-S223. Search in Google Scholar

Baponwa O, Amang AP, Mezui C, et al. Antioxidant mechanism of renal and hepatic failure prevention related to paracetamol overdose by the aqueous extract of Amblygonocarpus androgenesis stem bark. BioMed Research International, 2022:1846558. Search in Google Scholar

Gutiérrez-del-Río I, López-Ibáñez S, Magadán-Corpas P, et al. Terpenoids and Polyphenols as Natural Antioxidant Agents in Food Preservation. Antioxidants, 2021, 10(8): 1264. Search in Google Scholar

Wang M, Yu F, Zhang Y, et al. The effects and mechanisms of flavonoids on cancer prevention and therapy: focus on gut Microbiota. International Journal Biological Science, 2022, 18(4):1451-1475. Search in Google Scholar

Schneider CD, Bock PM, Becker GF. Comparison of the effects of two antioxidant diets on oxidative stress markers in triathletes. Biol Spor, 2018, 35(2):181–190. Search in Google Scholar

Vasconcelos TBC, Josino ARNR, Macena JB. Antioxidants and free radicals: Peril or protection? UNOPAR. Cient Ciênc Biol Saúde, 2014, 16(3): 213–190. Search in Google Scholar

Diaz-Del Corri E, Marinez de Toda L, Felix J, Baca A. Components of the glutathione cycle as markers of biological age: An Approach to Clinical Application in Aging. Antioxidants, 2023, 12(1529): 1-13. Search in Google Scholar

Akrami A, Nikaein F, Babajafari S. Comparison of the effects of flaxseed oil and sunflower seed oil consumption on serum glucose, lipid profile, blood pressure, and lipid peroxidation in patients with metabolic syndrome. J Clin Lipidol, 2018, 2(1):70–7. Search in Google Scholar

Viana ACC, MaiaFMM, Carvalho NS. Correlation between nutritional assessment and oxidative stress in candidates for liver transplant. Einstein, 2020, 18:eAO4039. Search in Google Scholar