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Unraveling the complexity of Stenotrophomonas maltophilia – a comprehensive review of current knowledge

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14 sept. 2024
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Summary of studies investigating antibiotic resistance of S_ maltophilia

Authors Year Antibiotic resistance findings
Rahmati-Bahram et al. [81] 1996 Investigated temperature-dependent aminoglycoside resistance in S. maltophilia, highlighting alterations in protein and lipopolysaccharide with growth temperature.
Avison et al. [76] 2000 Identified a TEM-2β-lactamase encoded on an active transposon in the genome of a clinical isolate of S. maltophilia.
Barbier-Frebour et al. [77] 2000 Explored the molecular mechanisms behind the rapid emergence of ticarcillin-clavulanate resistance in S. maltophilia isolates.
Zhang et al. [79] 2000 Involvement of a multidrug efflux system in multiple antibiotic resistance in S. maltophilia.
Alonso and Martínez [75] 2000 Cloning and characterization of SmeDEF, a multidrug efflux pump from S. maltophilia
Avison et al. [70] 2001 Plasmid location and molecular heterogeneity of beta-lactamase genes of S. maltophilia.
Poole [74] 2004 Efflux-mediated multiresistance in Gram-negative (G−) bacteria, including mechanisms in S. maltophilia.
Gülmez and Hasçelik [71] 2005 Antimicrobial resistance and molecular typing of S. maltophilia in a Turkish university hospital
Toleman et al. [78] 2007 Global emergence of trimethoprim/sulfamethoxazole resistance mediated by acquisition of sul genes in S. maltophilia.
Valenza et al. [80] 2008 Prevalence and antimicrobial susceptibility of microorganisms, including S. maltophilia, isolated from patients with cystic fibrosis.
Liaw et al. [72] 2010 Multidrug resistance in clinical isolates of S. maltophilia, including roles of integrons, efflux pumps, and biofilm formation.
Al Johani et al. [69] 2010 Prevalence of antimicrobial resistance among G− isolates in an adult intensive care unit, including S. maltophilia.
Hu et al. [82] 2011 S. maltophilia resistance to trimethoprim/sulfamethoxazole mediated by acquisition of sul and dfrA genes in a plasmid-mediated class 1 integron.