Technological Processing of Dried Powdered Rosehips to Tablets Through Wet Granulation
, , , , , , , et | 07 sept. 2023
À propos de cet article
Article Category: Original Paper
Publié en ligne: 07 sept. 2023
Pages: 12 - 20
Reçu: 19 oct. 2022
Accepté: 07 mai 2023
DOI: https://doi.org/10.2478/afpuc-2023-0061
Mots clés
© 2023 M. Špaglová et al., published by Sciendo
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Figure 1.
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Figure 4.
The content of vitamin C in Lactose Tablets (LAC TBL) and Microcrystalline Cellulose Tablets (MCC TBL).
| Content of vitamin C (µg) | 87.16 ± 5.06 | 63.33 ± 2.83 |
| % RSD | 5.80 | 4.47 |
The Quality Assessment of Lactose Tablets (LAC TBL) and Microcrystalline Cellulose Tablets (MCC TBL).
| Mass (g) | 0.320 ± 0.003 | 0.285 ± 0.003 |
| Height (mm) | 4.37 ± 0.02 | 4.10 ± 0.02 |
| Diameter (mm) | 9.09 ± 0.01 | 9.11 ± 0.01 |
| Resistance to crushing (N) | 64.80 ± 7.47 | 27.80 ± 2.15 |
| Friability (%) | 0.14 ± 0.07 | 1.15 ± 0.26 |
| Disintegration time (min) | more than 15 | 14.34 ± 0.50 |
The Composition of the Rosehip Granules: Lactose Granules (LAC GRA), Microcrystalline Cellulose (MCC GRA).
| 50.0 | 50.0 | |
| 50.0 | - | |
| - | 50.0 | |
The Quality Assessment of Lactose Granules (LAC GRA) and Microcrystalline Cellulose Granules (MCC GRA).
| Bulk density (g.cm−3) | 0.470 ± 0.018 | 0.474 ± 0.028 |
| Apparent specific volume (cm3.g−1) | 1.999 ± 0.039 | 1.942 ± 0.028 |
| Apparent density (g.cm−3) | 0.500 ± 0.010 | 0.515 ± 0.007 |
| Compressibility index (%) | 2.5 ± 0.0 | 5.0 ± 0.1 |
| Hausner ratio | 1.03 ± 0.00 | 1.05 ± 0.00 |
| Mechanical resistance (%) | 98.90 ± 0.60 | 99.59 ± 1.01 |
| Disintegration time (min) | more than 10 | more than 10 |
| Flow rate (g. s−1) | 4.49 ± 0.11 | 4.55 ± 0.10 |