<abstract xmlns="http://www.w3.org/1999/xhtml">

<p>Asthma is a heterogenous disease which pathophysiology is still poorly understood. Asthma was traditionally divided into allergic (extrinsic) and non-allergic (intrinsic) types, while patients with allergic type responded better to corticosteroids. Since 2013 the definition of asthma has changed. Recently, better insight into clinical consi -derations and underlying inflammatory phenotypes has been gained. Defining these phenotypes has already led to more specific clinical trials and, therefore, to more personalized and successfully targeted therapy. For future, much more effort is put in identifying new phenotype-specific biomarkers which could be helpful in stratification of heterogeneous patients with asthma.</p>
</abstract>

Asthma is a heterogenous disease which pathophysiology is still poorly understood. Asthma was traditionally divided into allergic (extrinsic) and non-allergic (intrinsic) types, while patients with allergic type responded better to corticosteroids. Since 2013 the definition of asthma has changed. Recently, better insight into clinical consi -derations and underlying inflammatory phenotypes has been gained. Defining these phenotypes has already led to more specific clinical trials and, therefore, to more personalized and successfully targeted therapy. For future, much more effort is put in identifying new phenotype-specific biomarkers which could be helpful in stratification of heterogeneous patients with asthma.

Bronchial Asthma: Current Trends in Treatment

Department of Physiology, Jessenius Faculty of Medicine in Martin

Department of Pharmacology, Jessenius Faculty of Medicine in Martin

Acta Medica Martiniana

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

{"article-title":"Bronchial Asthma: Current Trends in Treatment"}

Asthma is a heterogenous disease which pathophysiology is still poorly understood. Asthma was traditionally divided into allergic (extrinsic) and non-allergic...

Bronchial Asthma: Current Trends in Treatment

Publié en ligne: 30 avr. 2020

Pages: 9 - 17

Reçu: 28 oct. 2019

Accepté: 06 déc. 2019

DOI: https://doi.org/10.2478/acm-2020-0002

Mots clés
bronchial asthma, asthma phenotypes, asthma therapy

© 2020 R Palova et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Bronchial Asthma: Current Trends in Treatment

Publié en ligne: 30 avr. 2020

Pages: 9 - 17

Reçu: 28 oct. 2019

Accepté: 06 déc. 2019

DOI: https://doi.org/10.2478/acm-2020-0002

Mots clésbronchial asthma, asthma phenotypes, asthma therapy

© 2020 R Palova et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Mots clés
bronchial asthma, asthma phenotypes, asthma therapy