<abstract xmlns="http://www.w3.org/1999/xhtml"><p>When an antibody is detected, its specificity should be determined and its likely clinical significance should be assessed. When one antibody has been identified, it becomes necessary to confirm the presence of additional significant antibodies to ensure that compatible blood is provided to the patient. To perform this confirmation, specific reagent red blood cells (RBCs) are selected; these are called selected cells. Though the most common use of selected cells is for antibody confirmation, they can also be used for several other immunohematologic applications. In a developing country like India, the performance of antibody screening for unexpected antibodies on a routine basis is a comparatively new phenomenon, and those laboratories performing advanced immunohematologic testing would need to use selected cells to arrive at an accurate conclusion. This report defines selected cells and enumerates sources of these RBCs. Detailed immunohematologic applications are discussed with applicable case studies. <italic><bold>Immunohematology</bold></italic><bold>2017;33:27–35.</bold></p></abstract>

When an antibody is detected, its specificity should be determined and its likely clinical significance should be assessed. When one antibody has been identified, it becomes necessary to confirm the presence of additional significant antibodies to ensure that compatible blood is provided to the patient. To perform this confirmation, specific reagent red blood cells (RBCs) are selected; these are called selected cells. Though the most common use of selected cells is for antibody confirmation, they can also be used for several other immunohematologic applications. In a developing country like India, the performance of antibody screening for unexpected antibodies on a routine basis is a comparatively new phenomenon, and those laboratories performing advanced immunohematologic testing would need to use selected cells to arrive at an accurate conclusion. This report defines selected cells and enumerates sources of these RBCs. Detailed immunohematologic applications are discussed with applicable case studies. Immunohematology2017;33:27–35.

Applications of selected cells in immunohematology in a developing country: case studies

Immunohematology

When an antibody is detected, its specificity should be determined and its likely clinical significance should be assessed. When one antibody has been...

Applications of selected cells in immunohematology in a developing country: case studies

Article Category: Educational Forum

Publié en ligne: 09 oct. 2019

Pages: 27 - 35

DOI: https://doi.org/10.21307/immunohematology-2019-006

Mots clés
selected cells, immunohematology, unexpected antibody, alloimmunization

© 2017 R.C. Dara et al., published by Sciendo

Applications of selected cells in immunohematology in a developing country: case studies

Article Category: Educational Forum

Publié en ligne: 09 oct. 2019

Pages: 27 - 35

DOI: https://doi.org/10.21307/immunohematology-2019-006

Mots clésselected cells, immunohematology, unexpected antibody, alloimmunization

© 2017 R.C. Dara et al., published by Sciendo

Mots clés
selected cells, immunohematology, unexpected antibody, alloimmunization