Cephalometric assessment of soft tissue morphology of patients with acromegaly

Twenty-seven patients with acromegaly (11 male, 16 female; mean age 47.3 ± 11.5 years) and 30 healthy subjects (15 male, 15 female; mean age 42.2 ± 17.4 years) were included in the study. Linear and angular measurements were made on lateral cephalograms to evaluate soft tissue and skeletal characteristics. The intergroup comparisons were analysed with the Student’s t-test.

Results

Facial convexity (p < 0.01) and the nasolabial angle (p < 0.001) were reduced in patients with acromegaly, whereas nose prominence (p < 0.01), upper lip sulcus depth (p < 0.01), upper lip thickness (p < 0.01), basic upper lip thickness (p < 0.01), lower lip protrusion (p < 0.05), mentolabial sulcus depth (p < 0.05) and soft tissue chin thickness (p < 0.001) were increased. Anterior cranial base length (p < 0.05), the supraorbital ridge (p < 0.01), the length of the maxilla and mandible (p < 0.001, p < 0.01, respectively) were significantly increased, and mandibular prognathism was an acromegalic feature (p < 0.05).

Conclusion

Acromegalic coarsening and thickening of the craniofacial soft tissues was identified from lateral cephalograms, which may therefore contribute to early diagnosis when evaluated together with other changes caused by the disease.

eISSN:: 2207-7480
Langue:: Anglais

Périodicité:: Volume Open
Sujets de la revue:: Medicine, Basic Medical Science, other

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Cephalometric assessment of soft tissue morphology of patients with acromegaly

Publié en ligne: 30 juil. 2021

Pages: 48 - 54

Reçu: 01 août 2015

Accepté: 01 févr. 2016

DOI: https://doi.org/10.21307/aoj-2020-112

© 2016 Nehir Canigur Bavbek et al., published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.

Aim

Methods

Results

Conclusion