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Comparison between shear wave elastography and serological findings for the evaluation of fibrosis in chronic liver disease

Mahjabeen Liaqat
Mahjabeen Liaqat
, 
Kashif Siddique
Kashif Siddique
, 
Imran Yousaf
Imran Yousaf
, 
Raham Bacha
Raham Bacha
, 
S. Muhammad Yousaf Farooq
S. Muhammad Yousaf Farooq
 et 
Syed Amir Gilani
Syed Amir Gilani
   | 09 sept. 2021
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Article Category: research-article
Publié en ligne: 09 sept. 2021
Pages: 186 - 193
Reçu: 12 nov. 2020
Accepté: 11 mars 2021
DOI: https://doi.org/10.15557/jou.2021.0030
Mots clés
© 2021 Polish Ultrasound Society. Published by Medical Communications Sp. z o.o.
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Fig. 1.

Area under receiver operator curve for performance of APRI score in the prediction of F4 patients based on SWE
Area under receiver operator curve for performance of APRI score in the prediction of F4 patients based on SWE

Fig. 2.

Area under receiver operator curve for performance of FIB-4 score in the prediction of F4 patients based on SWE
Area under receiver operator curve for performance of FIB-4 score in the prediction of F4 patients based on SWE

Fig. 3.

Area under receiver operator curve for performance of APRI score in the prediction of F3–F4 based on SWE
Area under receiver operator curve for performance of APRI score in the prediction of F3–F4 based on SWE

Fig. 4.

Area under receiver operator curve for performance of FIB-4 score in the prediction of F3–F4 patients based on SWE
Area under receiver operator curve for performance of FIB-4 score in the prediction of F3–F4 patients based on SWE

Fig. 5.

Area under receiver operator curve for performance of APRI score in the prediction of F1–F4 patients based on SWE
Area under receiver operator curve for performance of APRI score in the prediction of F1–F4 patients based on SWE

Fig. 6.

Area under receiver operator curve for performance of FIB-4 score in the prediction of F1–F4 patients based on SWE
Area under receiver operator curve for performance of FIB-4 score in the prediction of F1–F4 patients based on SWE

Fig. 7.

SWE image showing liver fibrosis stage F4 with average median value of liver stiffness of about 17.9 kpa
SWE image showing liver fibrosis stage F4 with average median value of liver stiffness of about 17.9 kpa

Multiple comparisons for the descriptive variable FIB-4 in 5 stages of liver fibrosis

Mean difference among various stages of fibrosis with the help of multiple comparison test
Stages of fibrosis (I) Stages of fibrosis (J) Mean FIB-4 values difference (I-J) Std. error Sig. 95% confidence interval
Lower bound Upper bound
F0 F1 1.876 1.261 0.14 –0.635 4.388
F2 1.415 1.412 0.32 –1.397 4.228
F3 1.268 2.183 0.56 –3.082 5.617
F4 –0.204 1.128 0.86 –2.451 2.042
F1 F0 –1.876 1.261 0.14 –4.388 0.635
F2 –0.461 1.295 0.72 –3.040 2.118
F3 –0.609 2.109 0.77 –4.811 3.593
F4 –2.081* 0.976 0.04 –4.026 –0.136
F2 F0 –1.415 1.412 0.32 –4.228 1.397
F1 0.461 1.295 0.72 –2.118 3.040
F3 –0.148 2.203 0.95 –4.537 4.241
F4 –1.620 1.165 0.17 –3.941 0.702
F3 F0 –1.268 2.183 0.56 –5.617 3.082
F1 0.609 2.109 0.77 –3.593 4.811
F2 0.148 2.203 0.95 –4.241 4.537
F4 –1.472 2.033 0.47 –5.521 2.577
F4 F0 0.204 1.128 0.86 –2.042 2.451
F1 2.081* 0.976 0.04 0.136 4.026
F2 1.620 1.165 0.17 –0.702 3.941
F3 1.472 2.033 0.47 –2.577 5.521

Multiple comparisons for the descriptive variable APRI in 5 stages of liver fibrosis

Mean difference among various stages of fibrosis with the help of multiple comparison test
Stages of fibrosis (I) Stages of fibrosis (J) Mean FIB-4 values difference (I-J) Std. error Sig. 95% Confidence interval
Lower bound Upper bound
F0 F1 0.2500 0.3077 0.419 –0.3629 0.863
F2 0.1939 0.3446 0.575 –0.4926 0.880
F3 –0.3533 0.5329 0.509 –1.415 0.708
F4 –0.2625 0.2752 0.343 –0.8107 0.286
F1 F0 –0.2500 0.3077 0.419 –0.8629 0.363
F2 –0.0561 0.3159 0.860 –0.6855 0.573
F3 –0.6033 0.5149 0.245 –1.629 0.422
F4 –0.5125* 0.2383 0.035 –0.9873 –0.038
F2 F0 –0.1939 0.3446 0.575 –0.8805 0.493
F1 0.0561 0.3159 0.860 –0.5734 0.686
F3 –0.5473 0.5378 0.312 –1.618 0.524
F4 –0.4564 0.2844 0.113 –1.023 0.110
F3 F0 0.3533 0.5329 0.509 –0.7083 1.415
F1 0.6033 0.5149 0.245 –0.4223 1.629
F2 0.5473 0.5378 0.312 –0.5240 1.618
F4 0.0908 0.4961 0.855 –0.8975 1.079
F4 F0 0.2625 0.2752 0.343 –0.2857 0.811
F1 0.5125* 0.2383 0.035 0.0377 0.987
F2 0.4564 0.2844 0.113 –0.1101 1.023
F3 –0.0908 0.4961 0.855 –1.079 0.898
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