Olfaction and traumatic head injury - Is it possible to discriminate between malingering and patients with smell disorders based on nowadays knowledge?

1. Humme T., Landis B.N., Hüttenbrink K.B. - Smell and taste disorders. GMS Curr Top Otorhinolaryngol Head Neck Surg., 2011;10:Doc04. doi: 10.3205/cto000077.Search in Google Scholar

2. Zhao K., Scherer P.W., Hajiloo S.A., Dalton P. - Effect of anatomy on human nasal air flow and odorant transport patterns: implications for olfaction. Chem Senses., 2004;29(5):365-379. doi:10.1093/chemse/bjh033.10.1093/chemse/bjh033Search in Google Scholar

3. Damm M., Vent J., Schmidt M., Theissen P., Eckel H.E., Lotsch J., Hummel T. - Intranasal volume and olfactory function. Chem Senses., 2002;27(9):831-839. doi: 10.1093/chemse/27.9.831.10.1093/chemse/27.9.831Search in Google Scholar

4. Moulton D.G. - Dynamics of cell populations in the olfactory epithelium. Ann NY Acad Sci., 1974;237(0):52-61. doi: 10.1111/j.1749-6632.1974.tb49843.x.10.1111/j.1749-6632.1974.tb49843.xSearch in Google Scholar

5. Gradziadei P.P.C., Monti-Graziadei G.A. - Continuous nerve cell renewal in the olfactory system. In: Jacobson M., editor. - Handbook of sensory physiology. Volume IX. Development of Sensory Systems; Springer-Verlag, New York, 1978;pp.55-83.10.1007/978-3-642-66880-7_2Search in Google Scholar

6. Ohloff G. - Riechstoffe und Geruchssinn. Berlin: Springer Verlag, 1990.10.1007/978-3-662-09768-7Search in Google Scholar

7. Bignetti E., Cavaggioni A., Pelosi P., Persaud K.C., Sorbi R.T., Tirindelli R. - Purification and characterization of an odorant-binding protein from cow nasal tissue. Eur J Biochem., 1985;149(2):227-231. doi: 10.1111/j.1432-1033.1985.tb08916.x.10.1111/j.1432-1033.1985.tb08916.xSearch in Google Scholar

8. Briand L., Eloit C., Nespoulous C., Bezirard V., Huet J.C., Henry C., Blon F., Trotier D., Pernollet J.C. - Evidence of an odorant-binding protein in the human olfactory mucus: location, structural characterization, and odorant-binding properties. Biochemistry, 2002;41(23):7241-7252. doi: 10.1021/bi015916c.10.1021/bi015916cSearch in Google Scholar

9. Larsson M., Backman L. - Modality memory across the adult life span: evidence for selective age-related olfactory deficits. Exp Aging Res., 1998;24(1):63-82. doi: 10.1080/036107398244364.10.1080/036107398244364Search in Google Scholar

10. Hummel T., Futschik T., Frasnelli J., Huttenbrink K.B. - Effects of olfactory function, age, and gender on trigeminally mediated sensations: a study based on the lateralization of chemosensory stimuli. Toxicol Lett., 2003;140-141:273-280.10.1016/S0378-4274(03)00078-XSearch in Google Scholar

11. Hummel T. - Assessment of intranasal trigeminal function. Int J Psychophysiol., 2000;36(2):147-155.10.1016/S0167-8760(99)00108-7Search in Google Scholar

12. Doty R.L., Brugger W.E., Jurs P.C., Orndorff M.A., Snyder P.J., Lowry L.D. - Intranasal trigeminal stimulation from odorous volatiles: psychometric responses from anosmic and normal humans. Physiol Behav., 1978;20(2):175-185.Search in Google Scholar

13. Hummel T., Barz S., Lotsch J., Roscher S., Kettenmann B., Kobal. - Loss of olfactory function leads to a decrease of trigeminal sensitivity. Chem Senses, 1996;21(1):75-79.10.1093/chemse/21.1.75Search in Google Scholar

14. Gudziol H., Schubert M., Hummel T. - Decreased trigeminal sensitivity in anosmia. ORL J Otorhinolaryngol Relat Spec., 2001;63(2):72-75.Search in Google Scholar

15. Landis B.N., Hummel T., Lacroix J.S. - Basic and Clinical Aspects of Olfaction. Adv Tech Stand Neurosurg., 2005;30:69-105.Search in Google Scholar

16. Mozell M.M. - Evidence for sorption as a mechanism of the olfactory analysis of vapours. Nature, 1964;203:1181-1182.10.1038/2031181a0Search in Google Scholar

17. Mozell M.M., Jagodowicz M. - Chromatographic separation of odorants by the nose: retention times measured across in vivo olfactory mucosa. Science, 1973;181(4106):1247-1249.10.1126/science.181.4106.1247Search in Google Scholar

18. Amoore J.E. - Specific anosmia: a clue to the olfactory code. Nature, 1967;214(5093):1095-1098.10.1038/2141095a0Search in Google Scholar

19. Henning H. - Der Geruch. Johann Ambrosius Barth, Leipzig, 1916.Search in Google Scholar

20. Vassar R., Chao S.K., Sitcheran R., Nunez J.M., Vosshall L.B., Axel R. - Topographic organization of sensory projections to the olfactory bulb. Cell, 1994;79(6):981-991.10.1016/0092-8674(94)90029-9Search in Google Scholar

21. Nef P., Hermans-Borgmeyer I., Artieres-Pin H., Beasley L., Dionne V.E., Heinemann S.F. - Spatial pattern of receptor expression in the olfactory epithelium. Proc Natl Acad Sci U S A., 1992;89(19):8948-8952.Search in Google Scholar

22. Keller A., Vosshall L.B. - A psychophysical test of the vibration theory of olfaction. Nat Neurosci., 2004;7(4):337-338. Epub 2004 Mar 21.10.1038/nn1215Search in Google Scholar

23. Ressler K.J., Sullivan S.L., Buck L.B. - A zonal organization of odorant receptor gene expression in the olfactory epithelium. Cell, 1993;73(3):597-609.10.1016/0092-8674(93)90145-GSearch in Google Scholar

24. Buck L., Axel R. - A novel multigene family may encode odorant receptors: a molecular basis for odor recognition. Cell, 1991;65(1):175-187. doi: 10.1016/0092-8674(91)90418-X.10.1016/0092-8674(91)90418-XSearch in Google Scholar

25. Wenning G.K., Shephard B., Hawkes C., Petruckevitch A., Lees A., Quinn N.- Olfactory function in atypical parkinsonian syndromes. Acta Neurol Scand., 1995;91(4):247-250. doi: 10.1111/j.1600-0404.1995. tb06998.x.Search in Google Scholar

26. Welge-Lüssen A., Wattendorf E., Schwerdtfeger U., Fuhr P., Bilecen D., Hummel T., Westermann B. - Olfactory-induced brain activity in Parkinson’s disease relates to the expression of event-related potentials: a functional magnetic resonance imaging study. Neuroscience, 2009;162(2):537-543. doi: 10.1016/j.neuroscience.2009.04.050. Epub 2009 May 3.10.1016/j.neuroscience.2009.04.05019401224Search in Google Scholar

27. Nordin S., Paulsen J.S., Murphy C. - Sensory- and memory-mediated olfactory dysfunction in Huntington’s disease. J Int Neuropsychol Soc., 1995;1(13):281-290.Search in Google Scholar

28. Mesholam R.I., Moberg P.J., Mahr R.N., Doty R.L. - Olfaction in neurodegenerative disease: a meta-analysis of olfactory functioning in Alzheimer’s and Parkinson’s diseases. Arch Neurol.,1998;55(1):84-90. doi: 10.1001/archneur.55.1.84.10.1001/archneur.55.1.849443714Search in Google Scholar

29. Hawkes C. - Olfaction in neurodegenerative disorder. Adv Otorhinolaryngol., 2006;63:133-151.10.1159/00009375916733338Search in Google Scholar

30. Yamagishi M., Fujiwara M., Nakamura H.- Olfactory mucosal findings and clinical course in patients with olfactory disorders following upper respiratory viral infection. Rhinology, 1994;32(3):113-118.Search in Google Scholar

31. Delank K.W., Fechner G. - Zur Pathophysiologie der posttraumatischen Riechstörungen. Laryngol Rhinol Otol., 1996;75:154-159.Search in Google Scholar

32. Rombaux P., Mouraux A., Bertrand B., Nicolas G., Duprez T., Hummel T.- Retronasal and orthonasal olfactory function in relation to olfactory bulb volume in patients with posttraumatic loss of smell. Laryngoscope, 2006;116(6):901-905. doi: 10.1097/01.mlg.0000217533.60311.e7.10.1097/01.mlg.0000217533.60311.e716735894Search in Google Scholar

33. Kallmann F.J., Schoenfeld W.A., Barrera S.E. - The genetic aspects of primary eunuchoidism. Am J Ment Defic., 1944;48:203-236.Search in Google Scholar

34. Doty R.L., Philip S., Reddy K., Kerr K.L. - Influences of antihypertensive and antihyperlipidemic drugs on the senses of taste and smell: a review. J Hypertens., 2003;21(10):1805-1813.Search in Google Scholar

35. Kharoubi S. - Anosmie toxi-me´dicamenteuse a` la nife´dipine. Presse Med., 2003;32:1269-1272.Search in Google Scholar

36. Levenson J.L., Kennedy K. - Dysosmia, dysgeusia, and nifedipine. Ann Intern Med., 1985 102(1):135-136.10.7326/0003-4819-102-1-135_23966735Search in Google Scholar

37. Welge-Luessen A., Wolfensberger M. - Reversible anosmia after amikacin therapy. Arch Otolaryngol Head Neck Surg., 2003;129(12):1331-1333.Search in Google Scholar

38. Huart C., Rombaux P., Hummel T. - Plasticity of the human olfactory system: the olfactory bulb. Molecules, 2013;18(9):11586-11600. doi:10.3390/molecules180911586.10.3390/molecules180911586626982824048289Search in Google Scholar

39. Hummel T., Sekinger B., Wolf S.R., Pauli E., Kobal G. - “Sniffin’ Sticks”: Olfactory performance assessed by the combined testing of odor identification, odor discrimination and olfactory threshold. Chem Senses., 1997;22(1):39-52. doi: 10.1093/chemse/22.1.39.10.1093/chemse/22.1.399056084Search in Google Scholar

40. Kobal G., Klimek L., Wolfensberger M., Gudziol H., Temmel A., Owen C.M., Seeber H., Pauli E., Hummel T. - Multicenter investigation of 1,036 subjects using a standardized method for the assessment of olfactory function combining tests of odor identification, odor discrimination, and olfactory thresholds. Eur Arch Otorhinolaryngol., 2000;257(4):205-211.Search in Google Scholar

41. Hummel T., Konnerth C.G., Rosenheim K., Kobal G. - Screening of olfactory function with a four-minute odor identification test: reliability, normative data, and investigations in patients with olfactory loss. Ann Otol Rhinol Laryngol., 2001;110(10):976-981.Search in Google Scholar

42. Hummel T., Kobal G., Gudziol H., Mackay-Sim A. - Normative data for the “Sniffin’ Sticks” including tests of odor identification, odor discrimination, and olfactory thresholds: an upgrade based on a group of more than 3,000 subjects. Eur Arch Otorhinolaryngol., 2007;264(3):237-243. Epub 2006 Sep 23.10.1007/s00405-006-0173-017021776Search in Google Scholar

43. Heilmann S., Strehle G., Rosenheim K., Damm M., Hummel T. - Clinical assessment of retronasal olfactory function. Arch Otorhinolaryngol Head Neck Surg., 2002;128(4):414-418.Search in Google Scholar

44. Heilmann S., Hummel T. - A new method for comparing orthonasal and retronasal olfaction. Behav Neurosci., 2004;118(2):412-419.Search in Google Scholar

45. Picton T.W., Hillyard S.A. - Endogenous event-related potentials. In: Picton T.W. (ed) - Human event-related potentials. Elsevier Science, Amsterdam,1988;pp.361-426.Search in Google Scholar

46. Caminiti F., De Salvo S., De Cola M .C., Russo M., Bramanti P., Marino S., Ciurleo R. - Detection of olfactory dysfunction using olfactory event related potentials in young patients with multiple sclerosis. PLoS One., 2014;9(7):e103151. doi: 10.1371/journal.pone.0103151. eCollection 2014.10.1371/journal.pone.0103151410561625047369Search in Google Scholar

47. Barresi M., Ciurleo R., Giacoppo S., Foti Cuzzola V., Celi D., Bramanti P., Marino S. - Evaluation of olfactory dysfunction in neurodegenerative diseases. J Neurol Sci., 2012;323(1-2):16-24. doi: 10.1016/j. jns.2012.08.028. Epub 2012 Sep 23.Search in Google Scholar

48. Federico G., Maremmani C., Cinquanta L., Baroncelli G.I., Fattori B., Saggese G. - Mucus of the human olfactory epithelium contains the insulin- like growth factor-I system which is altered in some neurodegenerative diseases. Brain Res., 1999;835(2):306-314.Search in Google Scholar

49. Keller A., Zhuang H., Chi Q., Vosshall L.B., Matsunami H. - Genetic variation in a human odorant receptor alters odour perception. Nature, 2007;449(7161):468-172. doi:10.1038/nature0616210.1038/nature0616217873857Search in Google Scholar

50. Du G., Prestwich G.D. - Protein structure encodes the ligand binding specificity in pheromone binding proteins. Biochemistry, 1995;34(27):8726-8732.10.1021/bi00027a0237612612Search in Google Scholar

51. Frasnelli J., Lundstrom J.N., Boyle J.A., Djordjevic J., Zatorre R.J., Jones- Gotman M. - Neuroanatomical correlates of olfactory performance. Exp Brain Res., 2010;201(1):1-11. doi: 10.1007/s00221-009-1999-7.10.1007/s00221-009-1999-719730837Search in Google Scholar

52. Gottfried J.A., Winston J.S., Dolan R.J. - Dissociable codes of odor quality and odorant structure in human piriform cortex. Neuron., 2006;49(3):467-479.Search in Google Scholar

53. Shiga H., Taki J., Washiyama K., Yamamoto J., Kinase S., et al. - Assessment of olfactory nerve by SPECT-MRI image with nasal thallium-201 administration in patients with olfactory impairments in com parison to healthy volunteers. PloS One, 2013;8(2):e57671. doi: 10.1371/journal.pone.0057671.10.1371/journal.pone.0057671Search in Google Scholar

54. Eftekhari M., Assadi M., Kazemi M., Saghari M., Esfahani A.F., Sichani B.F., et al. - A preliminary study of neuroSPECT evaluation of patients with post-traumatic smell impairment. BMC Nucl Med., 2005;5:6.Search in Google Scholar

55. Small D.M., Jones-Gotman M., Zatorre R.J., Petrides M., Evans A.C. - Flavor processing: more than the sum of its parts. Neuroreport., 1997;8(18):3913-3917.Search in Google Scholar

56. Kareken D.A., Sabri M., Radnovich A.J., Claus E., Foresman B., Hector D., Hutchins G.D. -Olfactory system activation from sniffng: effects in piriform and orbitofrontal cortex. Neuroimage., 2004;22(1):456-465.Search in Google Scholar

57. Savic I., Berglund H. - Passive perception of odors and semantic circuits. Hum Brain Mapp., 2004;21(4):271-278.Search in Google Scholar

58. Kettenmann B., et al. - Magnetoencephalographical recordings: separation of cortical responses to different chemical stimulation in man. Funct Neurosci [EEG Suppl], 1996;46:287-290.Search in Google Scholar

59. Kettenmann B., Hummel C., Stefan H., Kobal G. - Multiple olfactory activity in the human neocortex identified by magnetic source imaging. Chem Senses., 1997;22(5):493-502.Search in Google Scholar

60. Iannilli E., Gerber J., Frasnelli J., Hummel T. - Intranasal trigeminal function in subjects with and without an intact sense of smell. Brain Res., 2007;1139:235-244. Epub 2007 Jan 5.10.1016/j.brainres.2006.12.082Search in Google Scholar

61. Feron F., Perry C., Cochrane J., Licina P., Nowitzke A., Urquhart S., Geraghty T., Mackay-Sim A. - Autologous olfactory ensheathing cell transplantation in human spinal cord injury. Brain, 2005;128(Pt 12):2951-2960. Epub 2005 Oct 11.10.1093/brain/awh657Search in Google Scholar

62. Haxel B.R., Murrell W.G., Mackay-Sim A. - Untersuchungen der Riechschleimhaut von anosmischen Patienten nach Schädel-Hirn- Trauma. HNO., 2005;53:688-689.Search in Google Scholar

63. Schriever V.A., Studt F., Smit M., Grosser K., Hummel T. - Olfactory function after mild head injury in children. Chem Senses., 2014;39(4):343-347. doi: 10.1093/chemse/bju005. Epub 2014 Feb 19.10.1093/chemse/bju005Search in Google Scholar

64. Gerami H., Nemati S., Abbaspour F., Banan R. - Brain single photon emission computed tomography in anosmic subjects after closed head trauma. Acta Med Iran., 2011;49(1):13-17.Search in Google Scholar

65. Schofield P.W., Moore T.M., Gardner A. - Traumatic brain injury and olfaction: a systematic review. Front Neurol., 2014;5:5. doi: 10.3389/ fneur.2014.00005.10.3389/fneur.2014.00005Search in Google Scholar

66. Bhatoe H.S. - Trauma to the cranial nerves. IJNT, 2007;4(2):89-100. 10.1016/S0973-0508(07)80022-0Search in Google Scholar