<abstract xmlns="http://www.w3.org/1999/xhtml"><bold>Aims</bold>. The aim of this study was to evaluate the association between neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR) and microalbuminuria in patients with normal estimated glomerular filtration rate (eGFR).<bold>Methods</bold>. 174 patients who had eGFR ≥ 60 mL/min/1.73 m2 were studied. Patients were divided into two groups according to the urinary albumin excretion as microalbuminuric group (n = 105) and normoalbuminuric group (n = 69). NLR and PLR levels were calculated.<bold>Results</bold>. NLR was significantly higher (p &lt; 0.05) in microalbuminuric patients (1.91 ± 0.70) compared with normoalbuminuric patients (1.63 ± 0.53). A positive correlation was found between urine albumin excretion and NLR in the whole study group (r = 0.214, p &lt; 0.005).<bold>Conclusions</bold>. Higher NLR levels were found in microalbuminuric patients with normal eGFR. Also a significant positive correlation was observed between albuminuria and NLR.</abstract>

Aims. The aim of this study was to evaluate the association between neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR) and microalbuminuria in patients with normal estimated glomerular filtration rate (eGFR).Methods. 174 patients who had eGFR ≥ 60 mL/min/1.73 m2 were studied. Patients were divided into two groups according to the urinary albumin excretion as microalbuminuric group (n = 105) and normoalbuminuric group (n = 69). NLR and PLR levels were calculated.Results. NLR was significantly higher (p < 0.05) in microalbuminuric patients (1.91 ± 0.70) compared with normoalbuminuric patients (1.63 ± 0.53). A positive correlation was found between urine albumin excretion and NLR in the whole study group (r = 0.214, p < 0.005).Conclusions. Higher NLR levels were found in microalbuminuric patients with normal eGFR. Also a significant positive correlation was observed between albuminuria and NLR.

Association of neutrophil-to-lymphocyte ratio and microalbuminuria in patients with normal eGFR

Department of Nephrology, Keçioren Education and Research Hospital

Department of Cardiology, Keçioren Education and Research Hospital

Department of Internal Medicine, Keçioren Education and Research Hospital

Romanian Journal of Internal Medicine

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Aims. The aim of this study was to evaluate the association between neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR) and...

Association of neutrophil-to-lymphocyte ratio and microalbuminuria in patients with normal eGFR

Publié en ligne: 07 mars 2018

Pages: 21 - 26

Reçu: 27 juil. 2017

DOI: https://doi.org/10.1515/rjim-2017-0036

Mots clés
Microalbuminuria, neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio

© 2017 Aysun Aybal Kutlugun et al., published by De Gruyter Open

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Association of neutrophil-to-lymphocyte ratio and microalbuminuria in patients with normal eGFR

Publié en ligne: 07 mars 2018

Pages: 21 - 26

Reçu: 27 juil. 2017

DOI: https://doi.org/10.1515/rjim-2017-0036

Mots clésMicroalbuminuria, neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio

© 2017 Aysun Aybal Kutlugun et al., published by De Gruyter Open

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Mots clés
Microalbuminuria, neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio