The present paper presents the method for obtaining core/shell CuO-ZnO nanoparticles and nanocoatings by using a commercially available vacuum coating system. Initially generated Cu-Zn core/shell nanoparticles have been oxidised with a highly reactive atomic oxygen beam. Second-harmonic generation has been observed in the obtained samples. The dependence of second- harmonic intensity on the wavelength of the exciting radiation is shown in the paper.