Observing the structure of employment and its trends constitute the fundamental baseline to assess the successes and failures of both national and EU social and economic policies in terms of evaluating effectiveness of support to regions framed by both competitiveness and cohesion issues. The study presents the assessment of structural changes of employment in the system of traditional three economic sectors using the measure of structures dissimilarity along with its decomposition and trends. The Czech NUTS 2 level regions were used for the study and the analysed period covered the years 2008−2014. The