The use of the Gelot emulsifier in diclofenac sodium semi-solid preparations

1. Alexander A. et al.: Approaches for breaking the barriers of drug permeation through transdermal drug delivery. J. Controlled Release, 164, 26, 2012.10.1016/j.jconrel.2012.09.017Search in Google Scholar

2. Asasutjarit R. et al.: Optimization and evaluation of thermoresponsive diclofenac sodium ophthalmic in situ gel. Int. J. Pharm., 411, 128, 2011.10.1016/j.ijpharm.2011.03.054Search in Google Scholar

3. Cal K.: Nowoczesne metody podawania substancji leczniczych przez skóręw nowych obszarach terapeutycznych na przykładzie transdermalnych systemów terapeutycznych (TTS). Aptekarz Polski, 70/48, 2012.Search in Google Scholar

4. Cal K., Stefanowska J.: Metody zwiększania przenikania substancji leczniczych przez skórę. Farmacja Polska, 66, 514, 2010.Search in Google Scholar

5. Cevc G., Blume G.: New, highly efficient formulation of diclofenac for the topical, transdermal administration in ultradeformable drug carriers. Transferosomes. Biochim. Biophys. Acta, 1514, 191, 2001.10.1016/S0005-2736(01)00369-8Search in Google Scholar

6. Chaudhary H., Kohli K., Kumar V.: Nano-transferosomes as a novel carrier for transdermal delivery. Int. J. Pharm., 454, 367, 2013.Search in Google Scholar

7. Chiarini A., Tartarini A., Fini A.: pH-solubility relationship and partition coefficients for some anti-inflammatory arylaliphatic acids. Arch. Pharm., 317, 268, 1984.Search in Google Scholar

8. Cordero J.A. et al.: A comparative study of the transdermal penetration of a series of nonsteroidal antiinflammatory drugs. J. Pharm. Sci., 86, 503, 1997.10.1021/js950346l9109056Search in Google Scholar

9. Farmakopea Polska X TOM I, (2014). Fizyczne i fizykochemiczne metody badania - Pomiar pH metodą potencjometryczną. Polskie Towarzystwo Farmaceutyczne, p. 110.Search in Google Scholar

10. Farmakopea Polska X TOM I, (2014). Metody badania postaci leku - Uwalnianie substancji czynnej z systemów transdermalnych. Polskie Towarzystwo Farmaceutyczne, p. 393.Search in Google Scholar

11. Fouad S.A. et al.: Microemulsion and poloxamer microemulsionbased gel for sustained transdermal delivery of diclofenac epolamine using in-skin drug depot: In vitro/in vivo evaluation. Int. J. Pharm., 45, 569, 2013.10.1016/j.ijpharm.2013.06.00923792042Search in Google Scholar

12. Fuller P., Roth S.: Diclofenac sodium topical solution with dimethyl sulfoxide, a viable alternative to oral nonsteroidal antiinflammatories in osteoarthritis: review of current evidence. J. Multidiscip. Healthc., 4, 223, 2011.Search in Google Scholar

13. Ioele G. et al.: The difficulties for a photolabile drug in topical formulations: The case of diclofenac. Int. J. Pharm., 465, 284, 2014.10.1016/j.ijpharm.2014.01.03024491531Search in Google Scholar

14. Kalhapure R.S., Akamanchi K.G.: Oleodendrimers: A novel class of multicephalous heterolipids as chemical penetration enhancers for transdermal drug delivery. Int. J. Pharm., 454, 158, 2013.Search in Google Scholar

15. Lane M.E.: Skin penetration enhancers. Int. J. Pharm. 447, 12, 2013.10.1016/j.ijpharm.2013.02.04023462366Search in Google Scholar

16. Łubkowska B., Grobelna B., Maćkiewicz Z.: Przenikanie składników aktywnych przez skórę. Pol. J. Cosmetol., 15, 33, 2012.Search in Google Scholar

17. Milao D. et al.: Hydrophilic gel containing nanocapsules of diclofenac: development, stability study and physico-chemical characterization. Pharmazie, 58, 325, 2003.Search in Google Scholar

18. Mohammadi R., Hirsaee M.A., Amini K.: Improvement of functional recoveryof transected peripheral nerve by means of artery grafts filled with diclofenac. Int. J. Surg., 11, 259, 2013.Search in Google Scholar

19. Mora M.J., Longhi M.R., Granero G.E.: Synthesis and characterization of binary and ternary complexes of diclofenac with a methyl-beta-CD and monoethanolamine and in vitro transdermal evaluation. Eur. J. Med. Chem., 45, 4079, 2010.Search in Google Scholar

20. Mudshinge S.R. et al.: Nanoparticles: emerging carries for drug delivery. Saudi Pharm. J. 19, 129, 2011.10.1016/j.jsps.2011.04.001374499923960751Search in Google Scholar

21. Pando D. et al.: Formulation of resveratrol entrapped niosomes for topical use. Colloids and Surfaces B: Biointerfaces, 128, 398, 2015.Search in Google Scholar

22. Pawlik-Gałczyńska A., Owczarek A., Pluta J.: Skóra jako droga podania substancji leczniczych. Część I. Budowa skóry, wchłanianie leków przez skórę. Farmacja Polska, 63, 287, 2007.Search in Google Scholar

23. Sayen S. et al.: A novel copper (II) mononuclear complex with the non-steroidal anti-inflammatory drug diclofenac: Structural characterization and biological activity. J. Inorganic Biochem., 120, 39, 2013.10.1016/j.jinorgbio.2012.12.00223280425Search in Google Scholar

24. Shahzad Y. et al.: Breaching the skin barrier through temperature modulations. J. Control Release, 202, 1, 2015.10.1016/j.jconrel.2015.01.01925616160Search in Google Scholar

25. Sharquie K.E. et al.: Treatment of pityriasis versicolor using 1% diclofenac gel and clotrimazole cream (comparative therapeutic study). J. Saudi Soc. Dermatol. Dermatol. Surg., 15, 19, 2011.10.1016/j.jssdds.2010.10.004Search in Google Scholar

26. Silva N.H.C.S. et al.: Bacterial cellulose membranes as transdermal delivery systems for diclofenac: In vitro dissolution and permeation studies. Carbohydrate Polymers, 106, 264, 2014.10.1016/j.carbpol.2014.02.01424721077Search in Google Scholar

27. Sintov A.C., Botner S.: Transdermal drug delivery using microemulsion and aqueous systems: influence of skin storage conditions on the in vitro permeability of diclofenac from aqueous vehicle systems. Int. J. Pharm., 311, 55, 2006.Search in Google Scholar

28. Technical data sheet - Gelot 64; http://www.gattefosse.com/Search in Google Scholar

29. Wadhawa J., Nair A., Kumira R.: Emulsion forming drug delivery system for lipophilic drugs. Acta Pol. Pharm., 69, 179, 2012.Search in Google Scholar

30. Zacher J. et al.: Topical diclofenac and its role in pain and inflammation: an evidence-based review. Curr. Med. Res. Opin., 24, 925, 2008.10.1185/030079908X273066Search in Google Scholar

31. Zgoda M.M., Kołodziejska J., Godlewska M. (2008). Metody badania wybranych środków farmaceutycznych i kosmetyków. Wydawnictwo Kwieciński p. 8.Search in Google Scholar