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Effect of the Pro12Ala polymorphism of the peroxisome proliferator-activated receptor γ2 gene on lipid profile and adipokines levels in obese subjects

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Stump M, Mukohda M, Hu C, Sigmund CD. PPARγ regulation in hypertension and metabolic syndrome. Curr Hypertens Rep. 2015; 17(12): 1-9.StumpMMukohdaMHuCSigmundCD. PPARγ regulation in hypertension and metabolic syndrome Curr Hypertens Rep. 2015 17 12 1 9Search in Google Scholar

Feige JN, Gelman L, Michalik L, Desvergne B, Wahli W. From molecular action to physiological outputs: Peroxisome proliferator-activated receptors are nuclear receptors at the crossroads of key cellular functions. Prog Lipid Res. 2006; 45(2): 120-159.FeigeJNGelmanLMichalikLDesvergneBWahliW. From molecular action to physiological outputs: Peroxisome proliferator-activated receptors are nuclear receptors at the crossroads of key cellular functions Prog Lipid Res. 2006 45 2 120 159Search in Google Scholar

Buzzetti R, Petrone A, Ribaudo MC, Alemanno I, Zavarella S, Mein CA, et al. The common PPAR-γ2 Pro12 Ala variant is associated with greater insulin sensitivity. Eur J Hum Genet. 2004; 12(12): 1050-1054.BuzzettiRPetroneARibaudoMCAlemannoIZavarellaSMeinCA The common PPAR-γ2 Pro12 Ala variant is associated with greater insulin sensitivity Eur J Hum Genet. 2004 12 12 1050 1054Search in Google Scholar

Kubota N, Terauchi Y, Miki H, Tamemoto H, Yamauchi T, Komeda K, et al. PPARγ mediates high-fat diet-induced adipocyte hypertrophy and insulin resistance. Mol Cell. 1999; 4(4): 597-609.KubotaNTerauchiYMikiHTamemotoHYamauchiTKomedaK PPARγ mediates high-fat diet-induced adipocyte hypertrophy and insulin resistance Mol Cell. 1999 4 4 597 609Search in Google Scholar

Elbrecht A, Chen Y, Cullinan CA, Hayes N, Leibowitz Md, Moller DE, et al. Molecular cloning, expression and characterization of human peroxisome proliferator activated receptors γ1 and γ2. Biochem Biophys Res Commun. 1996; 224(2): 431-437.ElbrechtAChenYCullinanCAHayesNLeibowitzMdMollerDE Molecular cloning, expression and characterization of human peroxisome proliferator activated receptors γ1 and γ2 Biochem Biophys Res Commun. 1996 224 2 431 437Search in Google Scholar

Yen CJ, Beamer BA, Negri C, Silver K, Brown KA, Yarnall DP, et al. Molecular scanning of the human peroxisome proliferator activated receptor γ (hPPARγ) gene in diabetic Caucasians: Identification of a Pro12Ala PPARγ2 missense mutation. Biochem Biophys Res Commun. 1997; 241(2): 270-274.YenCJBeamerBANegriCSilverKBrownKAYarnallDP Molecular scanning of the human peroxisome proliferator activated receptor γ (hPPARγ) gene in diabetic Caucasians: Identification of a Pro12Ala PPARγ2 missense mutation Biochem Biophys Res Commun. 1997 241 2 270 274Search in Google Scholar

Deeb SS, Fajas L, Nemoto M, Pihlajamäki J, Mykkänen L, Kuusisto J, et al. A Pro12Ala substitution in PPARγ2 associated with decreased receptor activity, lower body mass index and improved insulin sensitivity. Nat Genet. 1998; 20(3): 284-287.DeebSSFajasLNemotoMPihlajamäkiJMykkänenLKuusistoJ A Pro12Ala substitution in PPARγ2 associated with decreased receptor activity lower body mass index and improved insulin sensitivity Nat Genet. 1998 20 3 284 287Search in Google Scholar

Yao YS, Li J, Jin YL, Chen Y, He LP. Association between PPAR-γ2 Pro12Ala polymorphism and obesity: A meta-analysis. Mol Biol Rep. 2015; 42(6): 1029-1038.YaoYSLiJJinYLChenYHeLP. Association between PPAR-γ2 Pro12Ala polymorphism and obesity: A meta-analysis Mol Biol Rep. 2015 42 6 1029 1038Search in Google Scholar

Tönjes A, Stumvoll M. The role of the Pro12Ala polymorphism in peroxisome proliferator-activated receptor γ in diabetes risk. Curr Opin Clin Nutr Metab Care. 2007; 10(4): 410-414.TönjesAStumvollM. The role of the Pro12Ala polymorphism in peroxisome proliferator-activated receptor γ in diabetes risk Curr Opin Clin Nutr Metab Care. 2007 10 4 410 414Search in Google Scholar

Moon MK, Cho YM, Jung HS, Park YJ, Yoon KH, Sung YA, et al. Genetic polymorphisms in peroxisome proliferator-activated receptor γ are associated with type 2 diabetes mellitus and obesity in the Korean population. Diabet Med. 2005; 22(9): 1161-1166.MoonMKChoYMJungHSParkYJYoonKHSungYA Genetic polymorphisms in peroxisome proliferator-activated receptor γ are associated with type 2 diabetes mellitus and obesity in the Korean population Diabet Med. 2005 22 9 1161 1166Search in Google Scholar

Ghoussaini M, Meyre D, Lobbens S, Charpentier G, Clément K, Charles MA, et al. Implication of the Pro12Ala polymorphism of the PPAR-γ2 gene in type 2 diabetes and obesity in the French population. BMC Med Genet. 2005; 6(11): 1-8.GhoussainiMMeyreDLobbensSCharpentierGClémentKCharlesMA Implication of the Pro12Ala polymorphism of the PPAR-γ2 gene in type 2 diabetes and obesity in the French population BMC Med Genet. 2005 6 11 1 8Search in Google Scholar

Ben Ali S, Ben Yahia F, Sediri Y, Kallel A, Ftouhi B, Feki M, et al. Gender-specific effect of Pro12Ala polymorphism in peroxisome proliferator-activated receptor γ-2 gene on obesity risk and leptin levels in a Tunisian population. Clin Biochem. 2009; 42(16-17): 1642-1647.Ben AliSBen YahiaFSediriYKallelAFtouhiBFekiM Gender-specific effect of Pro12Ala polymorphism in peroxisome proliferator-activated receptor γ-2 gene on obesity risk and leptin levels in a Tunisian population Clin Biochem. 2009 42 16-17 16421647Search in Google Scholar

Takata N, Awata T, Inukai K, Watanabe M, Ohkubo T, Kurihara S, et al. Pro12Ala substitution in peroxisome proliferator-activated receptor γ2 is associated with low adiponectin concentrations in young Japanese men. Metabolism. 2004; 53(12): 1548-1551.TakataNAwataTInukaiKWatanabeMOhkuboTKuriharaS Pro12Ala substitution in peroxisome proliferator-activated receptor γ2 is associated with low adiponectin concentrations in young Japanese men Metabolism. 2004 53 12 1548 1551Search in Google Scholar

World Health Organization. Physical status: The use and interpretation anthropometry: Report of a WHO Expert Committee, WHO Technical Report Series, no. 854. Geneva, Switzerland: WHO. 1995; 321-344.World Health Organization Physical status: The use and interpretation anthropometry: Report of a WHO Expert Committee, WHO Technical Report Series, no. 854 Geneva, Switzerland WHO 1995 321344Search in Google Scholar

Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC. Homeostasis model assessment: Insulin resistance and β-cell function from fasting plasma glucose and insulin concentration in man. Diabetologia. 1985; 28(7): 412-419.MatthewsDRHoskerJPRudenskiASNaylorBATreacherDFTurnerRC. Homeostasis model assessment: Insulin resistance and β-cell function from fasting plasma glucose and insulin concentration in man Diabetologia. 1985 28 7 412 419Search in Google Scholar

Miller SA, Dykes DD, Polesky HF. A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res. 1988; 16(3): 1215.MillerSADykesDDPoleskyHF. A simple salting out procedure for extracting DNA from human nucleated cells Nucleic Acids Res. 988 16 3 1215Search in Google Scholar

Tellechea ML, Aranguren F, Perez MS, Cerrone GE, Frechtel GD, Taverna MJ. Pro12Ala polymorphism of the peroxisome proliferator activated receptor-γ gene is associated with metabolic syndrome and surrogate measures of insulin resistance in healthy men: Interaction with smoking status. Circ J. 2009; 73(11): 2118-2124.TellecheaMLArangurenFPerezMSCerroneGEFrechtelGDTavernaMJ. Pro12Ala polymorphism of the peroxisome proliferator activated receptor-γ gene is associated with metabolic syndrome and surrogate measures of insulin resistance in healthy men: Interaction with smoking status Circ J. 2009 73 11 2118 2124Search in Google Scholar

Beamer BA, Yen CJ, Andersen RE, Muller, Elahi D, Cheskin LJ, et al. Association of the Pro12Ala variant in the peroxisome proliferator-activated receptor-γ2 gene with obesity in two Caucasian populations. Diabetes. 1998; 47(11): 1806-1808.BeamerBAYenCJAndersenREMuller, ElahiDCheskinLJ Association of the Pro12Ala variant in the peroxisome proliferator-activated receptor-γ2 gene with obesity in two Caucasian populations Diabetes. 1998 47 11 1806 1808Search in Google Scholar

Masud S, Ye S; SAS Group. Effect of the peroxisome proliferator activated receptor-γ gene Pro12Ala variant on body mass index: A meta-analysis. J Med Genet. 2003; 40(10): 773-780.MasudSYeS SAS Group. Effect of the peroxisome proliferator activated receptor-γ gene Pro12Ala variant on body mass index: A meta-analysis J Med Genet. 2003 40 10 773 780Search in Google Scholar

Gonzalez Sanchez JL, Serrano Rios M, Fernandez Perez C, Laakso M, Martinez Larrad MT. Effect of the Pro12Ala polymorphism of the peroxisome proliferator activated receptor γ-2 gene on adiposity, insulin sensitivity and lipid profile in the Spanish population. Eur J Endocrinol. 2002; 147(4): 495-501.Gonzalez SanchezJLSerrano RiosMFernandez PerezCLaaksoMMartinez LarradMT. Effect of the Pro12Ala polymorphism of the peroxisome proliferator activated receptor γ-2 gene on adiposity, insulin sensitivity and lipid profile in the Spanish population Eur J Endocrinol. 2002 147 4 495 501Search in Google Scholar

Moffett SP, Feingold E, Barmada MM, Damcott CM, Marshall JA, Hamman RF, et al. The C161 → T polymorphism in peroxisome proliferator-activated receptor γ, but not P12A, is associated with insulin resistance in Hispanic and non-Hispanic white women: Evidence for another functional variant in peroxisome proliferator-activated receptor γ. Metabolism. 2005; 54(11): 1552-1556.MoffettSPFeingoldEBarmadaMMDamcottCMMarshallJAHammanRF The C161 → T polymorphism in peroxisome proliferator-activated receptor γ, but not P12A, is associated with insulin resistance in Hispanic and non-Hispanic white women: Evidence for another functional variant in peroxisome proliferator-activated receptor γ Metabolism. 2005 54 11 1552 1556Search in Google Scholar

Swarbrick MM, Chapman CM, McQuillan BM, Hung J, Thompson PL, Beilby JP. A Pro12Ala polymorphism in the human peroxisome proliferator-activated receptor-γ2 is associated with combined hyperlipidaemia in obesity. Eur J Endocrinol. 2001; 144(3): 277-282.SwarbrickMMChapmanCMMcQuillanBMHungJThompsonPLBeilbyJP. A Pro12Ala polymorphism in the human peroxisome proliferator-activated receptor-γ2 is associated with combined hyperlipidaemia in obesity Eur J Endocrinol. 2001 144 3 277 282Search in Google Scholar

Paracchini V, Pedotti P, Taioli E. Genetics of leptin and obesity: a HuGE review. Am J Epidemiol. 2005; 162(2): 101-114.ParacchiniVPedottiPTaioliE. Genetics of leptin and obesity: a HuGE review Am J Epidemiol. 2005 162 2 101 114Search in Google Scholar

Schneider J, Kreuzer J, Hamann A, Nawroth PP, Dugi KA. The proline 12 alanine substitution in the peroxisome proliferator – Activated receptor-γ2 gene is associated with lower lipoprotein lipase activity in vivo. Diabetes. 2002; 51(13): 867-870.SchneiderJKreuzerJHamannANawrothPPDugiKA. The proline 12 alanine substitution in the peroxisome proliferator – Activated receptor-γ2 gene is associated with lower lipoprotein lipase activity in vivo Diabetes. 2002 51 13 867 870Search in Google Scholar

Hollenberg AN, Susulic VS, Madura JP, Zhang B, Moller DE, Tontonoz P, et al. Functional antagonism between CCAAT/enhancer binding protein-α and peroxisome proliferator-activated receptor-γ on the leptin promoter. J Biol Chem. 1997; 272(8): 5283-5290.HollenbergANSusulicVSMaduraJPZhangBMollerDETontonozP Functional antagonism between CCAAT/enhancer binding protein-α and peroxisome proliferator-activated receptor-γ on the leptin promoter J Biol Chem. 1997 272 8 5283 5290Search in Google Scholar

Akune T, Ohba S, Kamekura S, Yamaguchi M, Chung UI, Kubota N, et al. PPARγ insufficiency enhances osteogenesis through osteoblast formation from bone marrow progenitors. J Clin Invest. 2004; 113(6): 846-855.AkuneTOhbaSKamekuraSYamaguchiMChungUIKubotaN PPARγ insufficiency enhances osteogenesis through osteoblast formation from bone marrow progenitors J Clin Invest. 2004 113 6 846855Search in Google Scholar

Simón I, Vendrell J, Gutiérrez C, Fernández-Real JM, Vendrell I, Gallart L, et al. Pro12Ala substitution in the peroxisome proliferator-activated receptor-γ is associated with increased leptin levels in women with type-2 diabetes mellitus. Horm Res. 2002; 58(3): 143-149.SimónIVendrellJGutiérrezC Fernández-RealJMVendrellIGallartL Pro12Ala substitution in the peroxisome proliferator-activated receptor-γ is associated with increased leptin levels in women with type-2 diabetes mellitus Horm Res. 2002 58 3 143 149Search in Google Scholar

Maeda N, Takahashi M, Funahashi T, Kihara S, Nishizawa H, Kishida K, et al. PPARγ ligands increase expression and plasma concentrations of adiponectin, an adipose-derived protein. Diabetes. 2001; 50(9): 2094-2099.MaedaNTakahashiMFunahashiTKiharaSNishizawaHKishidaK PPARγ ligands increase expression and plasma concentrations of adiponectin an adipose-derived protein Diabetes. 2001 50 9 2094 2099Search in Google Scholar

Moseti D, Regassa A, Kim WK. Molecular regulation of adipogenesis and potential anti-adipogenic bioactive molecules. Int J Mol Sci. 2016; 17(1): 1-24.MosetiDRegassaAKimWK. Molecular regulation of adipogenesis and potential anti-adipogenic bioactive molecules Int J Mol Sci. 2016 17 1 1 24Search in Google Scholar

Duncan BB, Schmidt MI, Pankow JS, Bang H, Couper D, Ballantyne CM, et al. Adiponectin and the development of type 2 diabetes: The atherosclerosis risk in communities study. Diabetes. 2004; 53(9): 2373-2478.DuncanBBSchmidtMIPankowJSBangHCouperDBallantyneCM Adiponectin and the development of type 2 diabetes: The atherosclerosis risk in communities study Diabetes. 2004 53 9 2373 2478Search in Google Scholar

Mousavinasab F, Tähtinen T, Jokelainen J, Koskela P, Vanhala M, Oikarinen J, et al. Common poly-morphisms (single-nucleotide polymorphisms SNP+45 and SNP+276) of the adiponectin gene regulate serum adiponectin concentrations and blood pressure in young Finnish men. Mol Genet Metab. 2005; 87(2): 147-151.MousavinasabFTähtinenTJokelainenJKoskelaPVanhalaMOikarinenJ Common poly-morphisms (single-nucleotide polymorphisms SNP+45 and SNP+276) of the adiponectin gene regulate serum adiponectin concentrations and blood pressure in young Finnish men Mol Genet Metab. 2005 87 2 147 151Search in Google Scholar

Bhatt SP, Misra A, Sharma M, Luthra K, Guleria R, Pandey RM. Ala/Ala genotype of Pro12Ala polymorphism in the peroxisome proliferator-activated receptor-γ2 gene is associated with obesity and insulin resistance in Asian Indians. Diabetes Technol Ther. 2012; 14(9): 828-834.BhattSPMisraASharmaMLuthraKGuleriaRPandeyRM. Ala/Ala genotype of Pro12Ala polymorphism in the peroxisome proliferator-activated receptor-γ2 gene is associated with obesity and insulin resistance in Asian Indians Diabetes Technol Ther. 2012 14 9 828 834Search in Google Scholar

Takata N, Awata T, Inukai K, Watanabe M, Ohkubo T, Kurihara S, et al. Pro12Ala substitution in peroxisome proliferator-activated receptor γ2 is associated with low adiponectin concentrations in young Japanese men. Metabolism. 2004; 53(12): 1548-1551.TakataNAwataTInukaiKWatanabeMOhkuboTKuriharaS Pro12Ala substitution in peroxisome proliferator-activated receptor γ2 is associated with low adiponectin concentrations in young Japanese men Metabolism. 2004 53 12 1548 1551Search in Google Scholar

Yamamoto Y, Hirose H, Miyashita K, Nishikai K, Saito I, Taniyama M, et al. PPAR(γ)2 gene Pro12Ala polymorphism may influence serum level of an adipocyte-derived protein, adiponectin, in the Japanese population. Metabolism. 2002; 51(11): 1407-1409.YamamotoYHiroseHMiyashitaKNishikaiKSaitoITaniyamaM PPAR(γ)2 gene Pro12Ala polymorphism may influence serum level of an adipocyte-derived protein, adiponectin, in the Japanese population Metabolism. 2002 51 11 1407 1409Search in Google Scholar

Vázquez-Del Mercado M, Guzmán-Ornelas MO, Corona Meraz FI, Ríos-Ibarra CP, Reyes-Serratos EA, Ruíz-Quezada SL, et al. The 482Ser of PPARGC1A and 12Pro of PPARG2 alleles are associated with reduction of metabolic risk factors even obesity in a Mexican-Mestizo population. Biomed Res Int. 2015: 1-14.Vázquez-Del MercadoM Guzmán-OrnelasMOCorona MerazFI Ríos-IbarraCP Reyes-SerratosEA Ruíz-QuezadaSL The 482Ser of PPARGC1A and 12Pro of PPARG2 alleles are associated with reduction of metabolic risk factors even obesity in a Mexican-Mestizo population Biomed Res Int. 2015 114Search in Google Scholar

Patel L, Buckels AC, Kinghorn IJ, Murdock PR, Holbrook JD, Plumpton C, et al. Resistin is expressed in human macrophages and directly regulated by PPARγ activators. Biochem Biophys Res Commun. 2003; 300(2): 472-476.PatelLBuckelsACKinghornIJMurdockPR HolbrookJDPlumptonC Resistin is expressed in human macrophages and directly regulated by PPARγ activators Biochem Biophys Res Commun. 2003 300 2 472 476Search in Google Scholar

Muruganandan S, Roman AA, Sinal CJ. Adipocyte differentiation of bone marrow-derived mesenchymal stem cells: Cross talk with the osteoblastogenic program. Cell Mol Life Sci. 2009; 66(2): 236-253.MuruganandanSRomanAASinalCJ. Adipocyte differentiation of bone marrow-derived mesenchymal stem cells: Cross talk with the osteoblastogenic program Cell Mol Life Sci. 2009 66 2 236 253Search in Google Scholar

Muruganandan S, Parlee SD, Rourke JL, Ernst MC, Goralski KB, Sinal CJ. Chemerin, a novel peroxisome proliferator-activated receptorγ (PPARγ) target gene that promotes mesenchymal stem cell adipogenesis. J Biol Chem. 2011; 286(27): 23982-23995.MuruganandanSParleeSDRourkeJLErnstMCGoralskiKBSinalCJ. Chemerin, a novel peroxisome proliferator-activated receptorγ (PPARγ) target gene that promotes mesenchymal stem cell adipogenesis J Biol Chem. 2011 286 27 23982 23995Search in Google Scholar

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