<abstract xmlns="http://www.w3.org/1999/xhtml"><p> The aim of the work was to study the effect of chronic social stress induced by increased population density, “crowding stress” on blood pressure and endothelial function of arteries of male normotensive Wistar and spontaneously hypertensive (SHR) rats. Based on the results, we assume that social stress-induced reduction in endothelium-dependent relaxation and increased blood pressure of SHR rats is most likely associated with decreased bioavailability of nitric oxide. </p></abstract>

The aim of the work was to study the effect of chronic social stress induced by increased population density, “crowding stress” on blood pressure and endothelial function of arteries of male normotensive Wistar and spontaneously hypertensive (SHR) rats. Based on the results, we assume that social stress-induced reduction in endothelium-dependent relaxation and increased blood pressure of SHR rats is most likely associated with decreased bioavailability of nitric oxide.

Effect of Chronic Social Stress on Endothelial Function of the Mesenteric Artery of Normotensive and Spontaneously Hypertensive Rats

Slovak Academy of Sciences, Institute of Experimental Pharmacology and Toxicology, Bratislava, Slovak Republic

Comenius University in Bratislava,Jessenius Faculty of Medicine in Martin, Institute of Pharmacology, Martin,

Slovak Academy of Sciences, Institute of Normal and Pathologycal Physiology, Bratislava,

Slovak Academy of Sciences, Institute of Experimental Pharmacology and Toxicology, Bratislava,

European Pharmaceutical Journal

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

The aim of the work was to study the effect of chronic social stress induced by increased population density, “crowding stress” on blood pressure and...

Effect of Chronic Social Stress on Endothelial Function of the Mesenteric Artery of Normotensive and Spontaneously Hypertensive Rats

Publié en ligne: 23 nov. 2016

Pages: 23 - 24

Reçu: 04 août 2016

Accepté: 12 août 2016

DOI: https://doi.org/10.1515/afpuc-2016-0010

Mots clés
Endothelium, SHR, Nitric Oxide, Social stress

© by B. Kaprinay

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Effect of Chronic Social Stress on Endothelial Function of the Mesenteric Artery of Normotensive and Spontaneously Hypertensive Rats

Publié en ligne: 23 nov. 2016

Pages: 23 - 24

Reçu: 04 août 2016

Accepté: 12 août 2016

DOI: https://doi.org/10.1515/afpuc-2016-0010

Mots clésEndothelium, SHR, Nitric Oxide, Social stress

© by B. Kaprinay

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Mots clés
Endothelium, SHR, Nitric Oxide, Social stress