Methods for preliminary determination of pemetrexed in macromolecular drug-carrier systems

1. R. Duncan, Polymer conjugates as anticancer nanomedicines, Nat. Rev. Cancer6 (2006) 688–701; DOI: 10.1038/Nrc1958.10.1038/nrc195816900224Search in Google Scholar

2. M. J. Vicent and R. Duncan, Polymer conjugates: nanosized medicines for treating cancer, Trends Biotechnol. 24 (2006) 39–47; DOI: 10.1016/j.tibtech.2005.11.006.10.1016/j.tibtech.2005.11.00616307811Search in Google Scholar

3. R. Haag and F. Kratz, Polymer the rapeutics: concepts and applications, Angew Chem. Int. Ed. Engl. 45 (2006) 1198–1215; DOI: 10.1002/anie.200502113.10.1002/anie.20050211316444775Search in Google Scholar

4. A. A. Adjei, Pemetrexed (ALIMTA), a novel multitargeted antineoplastic agent, Clin. Cancer Res.10 (2004) 4276–4280; DOI: 10.1158/1078-0432.CCR-040010.10.1158/1078-0432.CCR-04001015217974Search in Google Scholar

5. R. B. Zhao, N. Diop-Bove, M. Visentin and I. D. Goldman, Mechanisms of membrane transport of folates into cells and across epithelia, Ann. Rev. Nutr. 31 (2011) 177–201; DOI: 10.1146/annurev-nutr-072610-145133.10.1146/annurev-nutr-072610-145133388523421568705Search in Google Scholar

6. J. E. Nutt, A. R. Razak, K. O’Too le, F. Black, A. E. Quinn, A. H. Calvert, E. R. Plummer and J. Lunec, The role of folate receptor alpha (FR alpha) in the response of malignant pleural mesothelioma to pemetrexed-containing chemotherapy, Br. J. Cancer102 (2010) 553–560; DOI: 10.1038/sj.bjc.6605501.10.1038/sj.bjc.6605501282293820051956Search in Google Scholar

7. W. H. Schuette, A. Groschel, M. S ebastian, S. Andreas, T. Muller, F. Schneller, S. Guetz, C. Eschbach, S. Bohnet, M. I. Leschinger and M. Reck, A randomized phase II study of pemetrexed in combination with cisplatin or carboplatin as first-line therapy for patients with locally advanced or metastatic non-small-cell lung cancer, Clin. Lung Cancer14 (2013) 215–223; DOI: 10.1016/j.cllc.2012.10.001.10.1016/j.cllc.2012.10.00123332288Search in Google Scholar

8. O. Caffo, L. Fratino, R. Barbieri, A. Perin, T. Martini, T. Sava, R. Segati, E. Vaccher, F. Bernardo Bassan, A. Veccia, G. Pappagallo nad E. Galligioni, Pemetrexed as second-line chemotherapy for castration-resistant prostate cancer after docetaxel failure: results from a phase II study, Urol Oncol. 31 (2013) 180–186; DOI: 10.1016/j.urolonc.2010.11.012.10.1016/j.urolonc.2010.11.01221803618Search in Google Scholar

9. A. A. Adjei, Pharmacology and mechanism of action of pemetrexed, Clin. Lung Cancer5 (2004) 51–55; DOI: 10.3816/CLC.2004.s.003.10.3816/CLC.2004.s.003Search in Google Scholar

10. R. Budzynska, D. Nevozhay, U. Kanska, M. Jagiello, A. Opolski, J. Wietrzyk and J. Boratynski, Antitumor activity of mannan-methotrexate conjugate in vitro and in vivo, Oncol. Res. 16 (2007) 415–421.10.3727/00000000778398083718074676Search in Google Scholar

11. D. Nevozhay, R. Budzynska, U. Kanska, M. Jagiello, M. S. Omar, J. Boratynski and A. Opolski, Antitumor properties and toxicity of dextran-methotrexate conjugates are dependent on the molecular weight of the carrier, Anticancer Res. 26 (2006) 1135–1143.Search in Google Scholar

12. A. Homma, H. Sato, A. Okamachi, T. Emura, T. Ishizawa, T. Kato, T. Matsuura, S. Sato, T. Tamura, Y. Higuchi, T. Watanabe, H. Kitamura, K. Asanuma, T. Yamazaki, M. Ikemi, H. Kitagawa, T. Morikawa, H. Ikeya, K. Maeda, K. Takahashi, K. Nohmi, N. Izutani, M. Kanda, and R. Suzuki, Novel hyaluronic acid-methotrexate conjugates for osteoarthritis treatment, Bioorg. Med. Chem. 17 (2009) 4647–4656; DOI: 10.1016/j.bmc.2009.04.063.10.1016/j.bmc.2009.04.06319457673Search in Google Scholar

13. T. M. Goszczynski, B. Filip-Psurska, K. Kempinska, J. Wietrzyk and J. Boratynski, Hydroxyethyl starch as an effective methotrexate carrier in anticancer therapy, Pharmacol. Res. Perspect. 2 (2014) 1–8; DOI: 10.1002/prp2.47.10.1002/prp2.47418641525505592Search in Google Scholar

14. M. Westphal, M. F. James, S. Kozek-Langenecker, R. Stocker, B. Guidet and H. Van Aken, Hydroxyethyl starches: different products-different effects, Anesthesiology111 (2009) 187–202; DOI: 10.1097/ALN.0b013e3181a7ec82.10.1097/ALN.0b013e3181a7ec8219512862Search in Google Scholar

15. T. Masuko, A. Minami, N. Iwasaki, T. Majima, S. Nishimura and Y. C. Lee, Carbohydrate analysis by a phenol-sulfuric acid method in microplate format, Anal. Biochem. 339 (2005) 69–72; DOI: 10.1016/j.ab.2004.12.001.10.1016/j.ab.2004.12.00115766712Search in Google Scholar