<abstract xmlns="http://www.w3.org/1999/xhtml"><sec id="j_abm-2018-0030_s_005_w2aab3b7b5b1b6b1aab1c16b1Aa"><h3>Background</h3><p>Opisthorchiasis caused by <italic>Opisthorchis viverrini</italic> is a serious health issue in the Mekong basin region, resulting in a high prevalence of cholangiocarcinoma. Nakhon Phanom province had the highest prevalence of <italic>O. viverrini</italic> infection in Thailand at 60% of the surveyed population in 2009, despite the attempted control of opisthorchiasis for >50 years. Knowing risk factors for <italic>O. viverrini</italic> infection in Nakhon Phanom may lead to improved control and prevention of opisthorchiasis.</p></sec><sec id="j_abm-2018-0030_s_006_w2aab3b7b5b1b6b1aab1c16b2Aa"><h3>Objectives</h3><p>To determine risk factors for <italic>O. viverrini</italic> infection in Nakhon Phanom.</p></sec><sec id="j_abm-2018-0030_s_007_w2aab3b7b5b1b6b1aab1c16b3Aa"><h3>Methods</h3><p>We conducted a cross-sectional survey in Nakhon Phanom province from February to March 2014. The community was selected using a stratified random sampling method, and then, participants were selected by systematic random sampling. Individuals ≥15 years old were included. Knowledge of <italic>O. viverrini</italic> infection, and attitudes and practice to avoid it were assessed using a questionnaire. <italic>O. viverrini</italic> infection was determined by stool examination with a formalin–ether concentration method. Factors associated with the infection were determined using multivariate logistic regression analysis.</p></sec><sec id="j_abm-2018-0030_s_008_w2aab3b7b5b1b6b1aab1c16b4Aa"><h3>Results</h3><p>Of the 134 participants, 75 (56%) were infected with <italic>O. viverrini</italic>. In the multivariate logistic regression analysis, 3 independent factors were associated with <italic>O. viverrini</italic> infection: age ≥ 55 years, odds ratio (OR) adjusted 6.36 (95% confidence interval (CI) 1.28–31.66); consumption of chopped raw-fish salad (<italic>koi pla</italic>), OR adjusted 28.74 (95% CI 3.59–230.24); and perceived susceptibility, OR adjusted 0.15 (95% CI 0.03–0.74).</p></sec><sec id="j_abm-2018-0030_s_009_w2aab3b7b5b1b6b1aab1c16b5Aa"><h3>Conclusions</h3><p>Age ≥ 55 years, consuming <italic>koi pla</italic>, and perceived susceptibility were independently associated with <italic>O. viverrini</italic> infection in Nakhon Phanom.</p></sec></abstract>

BackgroundOpisthorchiasis caused by Opisthorchis viverrini is a serious health issue in the Mekong basin region, resulting in a high prevalence of cholangiocarcinoma. Nakhon Phanom province had the highest prevalence of O. viverrini infection in Thailand at 60% of the surveyed population in 2009, despite the attempted control of opisthorchiasis for >50 years. Knowing risk factors for O. viverrini infection in Nakhon Phanom may lead to improved control and prevention of opisthorchiasis.ObjectivesTo determine risk factors for O. viverrini infection in Nakhon Phanom.MethodsWe conducted a cross-sectional survey in Nakhon Phanom province from February to March 2014. The community was selected using a stratified random sampling method, and then, participants were selected by systematic random sampling. Individuals ≥15 years old were included. Knowledge of O. viverrini infection, and attitudes and practice to avoid it were assessed using a questionnaire. O. viverrini infection was determined by stool examination with a formalin–ether concentration method. Factors associated with the infection were determined using multivariate logistic regression analysis.ResultsOf the 134 participants, 75 (56%) were infected with O. viverrini. In the multivariate logistic regression analysis, 3 independent factors were associated with O. viverrini infection: age ≥ 55 years, odds ratio (OR) adjusted 6.36 (95% confidence interval (CI) 1.28–31.66); consumption of chopped raw-fish salad (koi pla), OR adjusted 28.74 (95% CI 3.59–230.24); and perceived susceptibility, OR adjusted 0.15 (95% CI 0.03–0.74).ConclusionsAge ≥ 55 years, consuming koi pla, and perceived susceptibility were independently associated with O. viverrini infection in Nakhon Phanom.

Risk factors for <italic>Opisthorchis viverrini</italic> infection in Nakhon Phanom, Thailand, where the infection is highly endemic

Tropical and Parasitic Diseases Research Unit, Graduate Studies Division

Faculty of Medicine, Mahasarakham University

Asian Biomedicine

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Risk factors for  infection in Nakhon Phanom, Thailand, where the infection is highly endemic

BackgroundOpisthorchiasis caused by Opisthorchis viverrini is a serious health issue in the Mekong basin region, resulting in a high prevalence of...

Risk factors for Opisthorchis viverrini infection in Nakhon Phanom, Thailand, where the infection is highly endemic

Article Category: Brief communication (original)

Publié en ligne: 31 déc. 2018

Pages: 45 - 51

DOI: https://doi.org/10.1515/abm-2018-0030

Mots clés
endemic diseases, opisthorchiasis, risk factors, trematode infections

© 2018 Songkran Nakbun et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Risk factors for Opisthorchis viverrini infection in Nakhon Phanom, Thailand, where the infection is highly endemic

Article Category: Brief communication (original)

Publié en ligne: 31 déc. 2018

Pages: 45 - 51

DOI: https://doi.org/10.1515/abm-2018-0030

Mots clésendemic diseases, opisthorchiasis, risk factors, trematode infections

© 2018 Songkran Nakbun et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Mots clés
endemic diseases, opisthorchiasis, risk factors, trematode infections