Revista y Edición

Volumen 70 (2021): Edición 2 (September 2021)

Volumen 70 (2021): Edición 1 (June 2021)

Volumen 69 (2020): Edición 4 (December 2020)

Volumen 69 (2020): Edición 3 (December 2020)

Volumen 69 (2020): Edición 2 (December 2020)

Volumen 69 (2020): Edición 1 (June 2020)

Volumen 68 (2019): Edición 4 (December 2019)

Volumen 68 (2019): Edición 3 (December 2019)

Volumen 68 (2019): Edición 2 (October 2019)

Volumen 68 (2019): Edición 1 (June 2019)

Detalles de la revista
Formato
Revista
eISSN
2247-059X
Publicado por primera vez
31 Jan 1951
Periodo de publicación
1 tiempo por año
Idiomas
Inglés

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Volumen 69 (2020): Edición 2 (December 2020)

Detalles de la revista
Formato
Revista
eISSN
2247-059X
Publicado por primera vez
31 Jan 1951
Periodo de publicación
1 tiempo por año
Idiomas
Inglés

Buscar

11 Artículos

Summary

Acceso abierto

Summary

Publicado en línea: 31 Dec 2020
Páginas: 67 - 68

Resumen

Editorial

Acceso abierto

Comorbidities, COPD and COVID 19

Publicado en línea: 31 Dec 2020
Páginas: 69 - 72

Resumen

Abstract

Coronavirus disease 2019 caused by the severe acute respiratory syndrome coronavirus 2 is one of the most pressing health care concerns in 2020. The continually growing number of new cases, the global outspread of the virus and the severity of the disease determined the World Health Organization to declare the outbreak a pandemic.

Twenty per cent of the patients present severe and critical forms that frequently require oxygen supplementation and intensive care unit admission. That is why, to provide optimal care, it is imperative to identify at-risk patients.

Patients with associated chronic diseases are more prone to develop severe and critical forms of the infection. Although the chronic pulmonary obstructive disease is present only in a limited number of coronavirus disease 2019 patients, it is most commonly associated with lung disease and a poor outcome than other comorbidities.

Palabras clave

  • COVID-19
  • COPD
  • comorbidities

Cuvinte-cheie

  • COVID 19
  • BPOC
  • comorbidități

Reviews

Acceso abierto

Challenges in the diagnosis, treatment and management of asthma during COVID-19 pandemic

Publicado en línea: 31 Dec 2020
Páginas: 73 - 80

Resumen

Abstract

People over the age of 65 and those suffering from chronic diseases, such as asthma, are part of the risk group for severe acute respiratory syndrome-COV-2 (SARS-CoV-2) infection. In the past, a connection between viral infections and asthma has been presented. Patients with asthma appear to be at risk of contracting viral infections, and also viruses can cause asthma exacerbations. Another concern during this period was about the chronic administration of corticosteroids in asthmatic patients, because of the consideration that corticosteroid therapy would decrease the immunity of these patients, thus increasing the risk of infections, including the infection with SARS-CoV-2. Thus, several questions have emerged about the role of corticosteroid therapy in the development of COVID-19 in patients undergoing corticosteroid treatment. Most guidelines recommend continuing the administration of chronic treatment to this category of patients. At the same time, the health system had to adapt to the situation caused by the COVID-19 pandemic and deviate from the standard methods of managing most chronic diseases and these changes had an impact on these category of patients.

Palabras clave

  • COVID-19
  • asthma
  • viral infections
  • corticotherapy

Cuvinte-cheie

  • COVID-19
  • astmul bronșic
  • infecții virale
  • corticoterapie

Original Papers

Acceso abierto

Systemic inflammation, TNM staging and survival in patients with lung cancer

Publicado en línea: 31 Dec 2020
Páginas: 81 - 86

Resumen

AbstractBackground

It is recognised that systemic inflammation plays an important role in the development and progression of lung cancer. Several affordable biomarkers could be used to evaluate systemic inflammation: neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR) and erythrocyte sedimentation rate (ESR). These biomarkers may be linked with survival in lung cancer.

Aim

To assess the relation between systemic inflammation evaluated by NLR, PLR and ESR, tumour nodes metastasis (TNM) staging and negative outcome in lung cancer.

Materials and methods

Patients with lung cancer were classified (7th TNM lung cancer staging) into two groups: Group A (resectable stages) and Group B (nonresectable stages). Each group was divided into two subsets: survivors (As, Bs) and deceased (Ad, Bd) patients. Complete blood count (CBC) and ESR were determined. NLR and PLR were calculated. NLR, PLR and ESR values were compared between the two groups and their subsets.

Results

102 consecutive patients completed the protocol. In Group A (31 patients): NLR: 2.74 (0.87–12.94), PLR: 33.95 (21.61–416.66), ESR: 35 mm/h (6–135). Subgroup As: NLR: 2.36 (0.87–8.36), PLR: 138.82 (21.61–416.66), ESR: 15 mm/h (6–110). Subgroup Ad: NLR: 2.77 (1.25–12.94), PLR: 132.57 (41.11–371.17), ESR: 62 mm/h (11–135). In Group B (71 patients): NLR: 3.51(0.76–25.60), PLR: 170.37 (3.38–651.25), ESR:40 mm/h (3–120). Subgroup Bs: NLR: 1.40 (1.32–1.73), PLR: 112.89 (91.14–140.54), ESR: 31 mm/h (9–90). Subgroup Bd: NLR: 3.59 (0.70–25.60), PLR: 183.50 (3.38–651.25), ESR: 44 mm/h (3–120). NLR and PLR values were significantly higher (p: 0.04; p: 0.05) in Group B versus Group A. No significant difference was noted for ESR values between the two groups. In patients with nonresectable stages who were deceased (subgroup Bd), NLR and PLR values were significantly higher (p: 0.01; p: 0.03) versus survivals. In patients with resectable stages who were deceased (subgroup Ad), only the ESR value was significantly higher versus survivals.

Conclusions

Systemic inflammation assessed by affordable biomarkers as NLR and PLR is more prominent in advanced, nonresectable lung cancer. It may be a contributor, along with TNM staging, to the poor outcome of patients with nonresectable lung cancer.

Clinical implication

NLR and PLR may represent a valuable additional tool in the clinical management of patients with nonresectable lung cancer.

Palabras clave

  • lung cancer
  • systemic inflammation
  • neutrophil-to-lymphocyte ratio
  • platelet-to-lymphocyte ratio

Cuvinte-cheie

  • cancer bronhopulmonar
  • inflamatie sistemica
  • raport neutrofile-limfocite
  • raport trombocite-limfocite
Acceso abierto

INSPIRO project – Educational intervention against non-adherence to inhalation therapy for Romanian asthma and COPD patients

Publicado en línea: 31 Dec 2020
Páginas: 87 - 96

Resumen

AbstractBackground

In the management of chronic respiratory diseases such as asthma and chronic obstructive pulmonary disease (COPD), adherence to therapy represents a key to success.

Objective

The objective was to increase adherence to treatment through the development of educational intervention (EI) for asthma and COPD, addressed to patients and general practitioners (GPs). The educational programme includes group educational sessions and educational materials and was carried out in five Romanian hospitals. The results were assessed through Test of Adherence to Inhalers (TAI) questionnaire.

Results

Of note, 347 GPs and 435 patients were included. Seventy-six per cent of the GPs considered that the main causes of non-adherence are the disease misunderstanding, difficulty of using inhaled medication, fear of adverse effects, the patient’s conviction that no medicine is useful for his illness and financial nature (20%). Fifty-five per cent of surveyed GPs believed that their patients always or most of the time adhere to inhaled therapy but 57% of the same surveyed GPs checked the inhalation technique of their patients sometimes, rarely or never. Only 44% of the GPs discussed with the pulmonologist about their patient’s disease. Before the EI, only 32% of patients had a good adherence score to therapy; this percentage increases to 57% after EI. The most common reasons for non-adherence were: patient forgets to administer his inhalation medication daily (49%), fear of adverse effects (33%), belief that medication is useless (26%), and fear that inhalation medication affects everyday life of the patient (24%). Nearly half of the patients (47%) give up medication when they feel better. Forty per cent of patients drop off inhalation treatments due to financial reasons. The most influenced behaviours as a result of the EI were psychological component (85%), fear of the adverse events (82%) and social component (79%).

Conclusions

The non-adherence to therapy remains a real problem in asthma and COPD patients in our study group, but EI had positive effects. Extending medical education programmes for patients focused on main reasons of poor adherence, such as forgetting to take medication daily, use of inhalator devices, not understanding their disease, may significantly increase adherence to inhalation treatment.

Palabras clave

  • adherence
  • asthma
  • COPD

Cuvinte-cheie

  • aderare
  • astm
  • BPOC
Acceso abierto

Management of neoplastic pericarditis – overview of 156 patients

Publicado en línea: 31 Dec 2020
Páginas: 97 - 102

Resumen

AbstractIntroduction

Neoplastic pericarditis may develop in any type of cancer, but it is found more frequently in lung cancer, breast cancer and lymphoma.

Methods

We studied 156 consecutive oncological patients presented with pericardial fluid between 2010 and 2015. Among them, 80 patients were stable, with no indication for pericardial drainage or biopsy, and 76 patients needed surgery to evacuate the pericardium and obtain biopsy.

Results

Echocardiography and computed tomography were essential in evaluating the topography of the pericardial fluid and the haemodynamic effect, and these investigations helped us choose the appropriate surgical procedure. We performed pericardiocentesis, subxiphoid pericardial drainage, left paraxifoidian pericardial drainage, pericardio-pleural window through intercostal video-assisted thoracic surgery (VATS) or through classical thoracic surgery. Twenty-three patients (14.7%) were admitted and treated for cardiac tamponade. The rate of recurrence after pericardial drainage was 3.89%. The immediate survival at 48 h was 97.3%.

Conclusion

Long-term survival in patients with malignancy and drained pericardial effusion is influenced mainly by the type of underlying malignant disease. We observed a better survival in patients without cardiac tamponade. Immediate survival depends on the pericardial shock complication – postoperative low cardiac output syndrome (LCOS) or pericardial decompression syndrome (PDS). The indication for pericardial drainage depends on the quantity of pericardial fluid, presence of tamponade, associated pleural effusion and need for biopsy, offering the maximum possible benefit and safety for the patient.

Palabras clave

  • neoplastic pericardial effusion
  • cardiac tamponade
  • surgical pericardial drainage
  • video-assisted thoracic surgery (VATS)
  • pericardial fenestration
  • subxiphoidian pericardial drainage
  • paraxiphoidian pericardial drainage

Cuvinte-cheie

  • pericardita neoplazica
  • tamponada cardiaca
  • drenaj pericardic
  • fenestrare pericardica prin chirurgie toracica video-asistata CTVA
  • drenaj pericardic subxifoidian
  • drenaj pericardic paraxifoidian

Clinical Cases

Acceso abierto

Pulmonary artery thrombosis in home patient with a mild COVID-19 disease

Publicado en línea: 31 Dec 2020
Páginas: 103 - 106

Resumen

Abstract

COVID-19 has been described as the cause for a proinflammatory and hypercoagulable state that induces thrombotic vascular lesions and, in more severe cases, disseminated intravascular coagulation. Increased values of d-dimers are related to the severity of the disease and are associated with worst prognosis. Intensive care studies reported an increased risk of pulmonary embolism and venous thrombosis diseases in COVID-19 compared with the historical control group even in patients who underwent the low-molecular-weight heparin (LWMH) prophylaxis. Patients with COVID-19 who have a stable clinical condition do not require hospitalisation and are treated at home with symptomatic therapy. LWMH is reserved for those with reduced mobility. In this case report, we describe a COVID-19 patient with pulmonary artery thrombosis treated at home.

Palabras clave

  • COVID-19
  • -dimers
  • pulmonary artery thrombosis
  • interstitial pneumonia

Cuvinte-cheie

  • COVID-19
  • D-dimeri
  • tromboză arterială pulmonară
  • pneumonie interstițială
Acceso abierto

An atypical case: RT-PCR-negative, sero-positive covid-19 patient

Publicado en línea: 31 Dec 2020
Páginas: 107 - 114

Resumen

Abstract

The novel coronavirus disease-2019 (COVID-19), caused by the severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2), has become a public health emergency of international concern. The first confirmed COVID-19 case in Indonesia was announced on 2 March 2020, and later on, 11,192 confirmed cases were reported as of 3 May. The World Health Organization has stated that performing a real-time reverse transcription–polymerase chain reaction (RT-PCR) specific for SARS-CoV-2 on specimens from the upper and the lower respiratory tracts, especially nasopharyngeal and oropharyngeal swabs, is the standard diagnostic procedure for COVID-19. In Indonesia, we also use other diagnostic tests, such as rapid antibody tests specific for SARS-CoV-2. Herein, we report an atypical case of COVID-19 and describe the diagnostic process, the clinical course, with progression to severe pneumonia on Week 3 of illness and the case management. We also try to highlight the possibility of false-negative RT-PCR tests.

Palabras clave

  • COVID-19
  • SARS-CoV-2
  • RT-PCR
  • atypical case
  • sero-positive

Cuvinte-cheie

  • COVID-19
  • SARS-COV2
  • RT-PCR
  • Caz atipic
  • Seropozitiv

Smoking Problems

Acceso abierto

COVID 19 - a new threat for smokers and vapers?

Publicado en línea: 31 Dec 2020
Páginas: 115 - 118

Resumen

Abstract

The new pandemic disease Covid-19 compelled all the researchers to investigate for early identification of the potential risk factors. Further, the relation between smoking and infections are well known. The authors are trying to find the epidemiological links, the pathogenic mechanisms and also the impact of this coronavirus on different respiratory chronic diseases, based on the last published data about the consequences of smoking and vaping on consumers.

Palabras clave

  • vaping
  • e cigarette
  • smoking
  • COVID-19

Cuvinte-cheie

  • vaping
  • tigara electronică
  • fumatul
  • COVID-19
Acceso abierto

No Tobacco Day 2020 – another ancient ‘COVID DAY’?

Publicado en línea: 31 Dec 2020
Páginas: 119 - 121

Resumen

Romanian Society of Pneumology Activities

Acceso abierto

Romanian Society of Pneumology respect its traditional activities

Publicado en línea: 31 Dec 2020
Páginas: 122 - 125

Resumen

11 Artículos

Summary

Acceso abierto

Summary

Publicado en línea: 31 Dec 2020
Páginas: 67 - 68

Resumen

Editorial

Acceso abierto

Comorbidities, COPD and COVID 19

Publicado en línea: 31 Dec 2020
Páginas: 69 - 72

Resumen

Abstract

Coronavirus disease 2019 caused by the severe acute respiratory syndrome coronavirus 2 is one of the most pressing health care concerns in 2020. The continually growing number of new cases, the global outspread of the virus and the severity of the disease determined the World Health Organization to declare the outbreak a pandemic.

Twenty per cent of the patients present severe and critical forms that frequently require oxygen supplementation and intensive care unit admission. That is why, to provide optimal care, it is imperative to identify at-risk patients.

Patients with associated chronic diseases are more prone to develop severe and critical forms of the infection. Although the chronic pulmonary obstructive disease is present only in a limited number of coronavirus disease 2019 patients, it is most commonly associated with lung disease and a poor outcome than other comorbidities.

Palabras clave

  • COVID-19
  • COPD
  • comorbidities

Cuvinte-cheie

  • COVID 19
  • BPOC
  • comorbidități

Reviews

Acceso abierto

Challenges in the diagnosis, treatment and management of asthma during COVID-19 pandemic

Publicado en línea: 31 Dec 2020
Páginas: 73 - 80

Resumen

Abstract

People over the age of 65 and those suffering from chronic diseases, such as asthma, are part of the risk group for severe acute respiratory syndrome-COV-2 (SARS-CoV-2) infection. In the past, a connection between viral infections and asthma has been presented. Patients with asthma appear to be at risk of contracting viral infections, and also viruses can cause asthma exacerbations. Another concern during this period was about the chronic administration of corticosteroids in asthmatic patients, because of the consideration that corticosteroid therapy would decrease the immunity of these patients, thus increasing the risk of infections, including the infection with SARS-CoV-2. Thus, several questions have emerged about the role of corticosteroid therapy in the development of COVID-19 in patients undergoing corticosteroid treatment. Most guidelines recommend continuing the administration of chronic treatment to this category of patients. At the same time, the health system had to adapt to the situation caused by the COVID-19 pandemic and deviate from the standard methods of managing most chronic diseases and these changes had an impact on these category of patients.

Palabras clave

  • COVID-19
  • asthma
  • viral infections
  • corticotherapy

Cuvinte-cheie

  • COVID-19
  • astmul bronșic
  • infecții virale
  • corticoterapie

Original Papers

Acceso abierto

Systemic inflammation, TNM staging and survival in patients with lung cancer

Publicado en línea: 31 Dec 2020
Páginas: 81 - 86

Resumen

AbstractBackground

It is recognised that systemic inflammation plays an important role in the development and progression of lung cancer. Several affordable biomarkers could be used to evaluate systemic inflammation: neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR) and erythrocyte sedimentation rate (ESR). These biomarkers may be linked with survival in lung cancer.

Aim

To assess the relation between systemic inflammation evaluated by NLR, PLR and ESR, tumour nodes metastasis (TNM) staging and negative outcome in lung cancer.

Materials and methods

Patients with lung cancer were classified (7th TNM lung cancer staging) into two groups: Group A (resectable stages) and Group B (nonresectable stages). Each group was divided into two subsets: survivors (As, Bs) and deceased (Ad, Bd) patients. Complete blood count (CBC) and ESR were determined. NLR and PLR were calculated. NLR, PLR and ESR values were compared between the two groups and their subsets.

Results

102 consecutive patients completed the protocol. In Group A (31 patients): NLR: 2.74 (0.87–12.94), PLR: 33.95 (21.61–416.66), ESR: 35 mm/h (6–135). Subgroup As: NLR: 2.36 (0.87–8.36), PLR: 138.82 (21.61–416.66), ESR: 15 mm/h (6–110). Subgroup Ad: NLR: 2.77 (1.25–12.94), PLR: 132.57 (41.11–371.17), ESR: 62 mm/h (11–135). In Group B (71 patients): NLR: 3.51(0.76–25.60), PLR: 170.37 (3.38–651.25), ESR:40 mm/h (3–120). Subgroup Bs: NLR: 1.40 (1.32–1.73), PLR: 112.89 (91.14–140.54), ESR: 31 mm/h (9–90). Subgroup Bd: NLR: 3.59 (0.70–25.60), PLR: 183.50 (3.38–651.25), ESR: 44 mm/h (3–120). NLR and PLR values were significantly higher (p: 0.04; p: 0.05) in Group B versus Group A. No significant difference was noted for ESR values between the two groups. In patients with nonresectable stages who were deceased (subgroup Bd), NLR and PLR values were significantly higher (p: 0.01; p: 0.03) versus survivals. In patients with resectable stages who were deceased (subgroup Ad), only the ESR value was significantly higher versus survivals.

Conclusions

Systemic inflammation assessed by affordable biomarkers as NLR and PLR is more prominent in advanced, nonresectable lung cancer. It may be a contributor, along with TNM staging, to the poor outcome of patients with nonresectable lung cancer.

Clinical implication

NLR and PLR may represent a valuable additional tool in the clinical management of patients with nonresectable lung cancer.

Palabras clave

  • lung cancer
  • systemic inflammation
  • neutrophil-to-lymphocyte ratio
  • platelet-to-lymphocyte ratio

Cuvinte-cheie

  • cancer bronhopulmonar
  • inflamatie sistemica
  • raport neutrofile-limfocite
  • raport trombocite-limfocite
Acceso abierto

INSPIRO project – Educational intervention against non-adherence to inhalation therapy for Romanian asthma and COPD patients

Publicado en línea: 31 Dec 2020
Páginas: 87 - 96

Resumen

AbstractBackground

In the management of chronic respiratory diseases such as asthma and chronic obstructive pulmonary disease (COPD), adherence to therapy represents a key to success.

Objective

The objective was to increase adherence to treatment through the development of educational intervention (EI) for asthma and COPD, addressed to patients and general practitioners (GPs). The educational programme includes group educational sessions and educational materials and was carried out in five Romanian hospitals. The results were assessed through Test of Adherence to Inhalers (TAI) questionnaire.

Results

Of note, 347 GPs and 435 patients were included. Seventy-six per cent of the GPs considered that the main causes of non-adherence are the disease misunderstanding, difficulty of using inhaled medication, fear of adverse effects, the patient’s conviction that no medicine is useful for his illness and financial nature (20%). Fifty-five per cent of surveyed GPs believed that their patients always or most of the time adhere to inhaled therapy but 57% of the same surveyed GPs checked the inhalation technique of their patients sometimes, rarely or never. Only 44% of the GPs discussed with the pulmonologist about their patient’s disease. Before the EI, only 32% of patients had a good adherence score to therapy; this percentage increases to 57% after EI. The most common reasons for non-adherence were: patient forgets to administer his inhalation medication daily (49%), fear of adverse effects (33%), belief that medication is useless (26%), and fear that inhalation medication affects everyday life of the patient (24%). Nearly half of the patients (47%) give up medication when they feel better. Forty per cent of patients drop off inhalation treatments due to financial reasons. The most influenced behaviours as a result of the EI were psychological component (85%), fear of the adverse events (82%) and social component (79%).

Conclusions

The non-adherence to therapy remains a real problem in asthma and COPD patients in our study group, but EI had positive effects. Extending medical education programmes for patients focused on main reasons of poor adherence, such as forgetting to take medication daily, use of inhalator devices, not understanding their disease, may significantly increase adherence to inhalation treatment.

Palabras clave

  • adherence
  • asthma
  • COPD

Cuvinte-cheie

  • aderare
  • astm
  • BPOC
Acceso abierto

Management of neoplastic pericarditis – overview of 156 patients

Publicado en línea: 31 Dec 2020
Páginas: 97 - 102

Resumen

AbstractIntroduction

Neoplastic pericarditis may develop in any type of cancer, but it is found more frequently in lung cancer, breast cancer and lymphoma.

Methods

We studied 156 consecutive oncological patients presented with pericardial fluid between 2010 and 2015. Among them, 80 patients were stable, with no indication for pericardial drainage or biopsy, and 76 patients needed surgery to evacuate the pericardium and obtain biopsy.

Results

Echocardiography and computed tomography were essential in evaluating the topography of the pericardial fluid and the haemodynamic effect, and these investigations helped us choose the appropriate surgical procedure. We performed pericardiocentesis, subxiphoid pericardial drainage, left paraxifoidian pericardial drainage, pericardio-pleural window through intercostal video-assisted thoracic surgery (VATS) or through classical thoracic surgery. Twenty-three patients (14.7%) were admitted and treated for cardiac tamponade. The rate of recurrence after pericardial drainage was 3.89%. The immediate survival at 48 h was 97.3%.

Conclusion

Long-term survival in patients with malignancy and drained pericardial effusion is influenced mainly by the type of underlying malignant disease. We observed a better survival in patients without cardiac tamponade. Immediate survival depends on the pericardial shock complication – postoperative low cardiac output syndrome (LCOS) or pericardial decompression syndrome (PDS). The indication for pericardial drainage depends on the quantity of pericardial fluid, presence of tamponade, associated pleural effusion and need for biopsy, offering the maximum possible benefit and safety for the patient.

Palabras clave

  • neoplastic pericardial effusion
  • cardiac tamponade
  • surgical pericardial drainage
  • video-assisted thoracic surgery (VATS)
  • pericardial fenestration
  • subxiphoidian pericardial drainage
  • paraxiphoidian pericardial drainage

Cuvinte-cheie

  • pericardita neoplazica
  • tamponada cardiaca
  • drenaj pericardic
  • fenestrare pericardica prin chirurgie toracica video-asistata CTVA
  • drenaj pericardic subxifoidian
  • drenaj pericardic paraxifoidian

Clinical Cases

Acceso abierto

Pulmonary artery thrombosis in home patient with a mild COVID-19 disease

Publicado en línea: 31 Dec 2020
Páginas: 103 - 106

Resumen

Abstract

COVID-19 has been described as the cause for a proinflammatory and hypercoagulable state that induces thrombotic vascular lesions and, in more severe cases, disseminated intravascular coagulation. Increased values of d-dimers are related to the severity of the disease and are associated with worst prognosis. Intensive care studies reported an increased risk of pulmonary embolism and venous thrombosis diseases in COVID-19 compared with the historical control group even in patients who underwent the low-molecular-weight heparin (LWMH) prophylaxis. Patients with COVID-19 who have a stable clinical condition do not require hospitalisation and are treated at home with symptomatic therapy. LWMH is reserved for those with reduced mobility. In this case report, we describe a COVID-19 patient with pulmonary artery thrombosis treated at home.

Palabras clave

  • COVID-19
  • -dimers
  • pulmonary artery thrombosis
  • interstitial pneumonia

Cuvinte-cheie

  • COVID-19
  • D-dimeri
  • tromboză arterială pulmonară
  • pneumonie interstițială
Acceso abierto

An atypical case: RT-PCR-negative, sero-positive covid-19 patient

Publicado en línea: 31 Dec 2020
Páginas: 107 - 114

Resumen

Abstract

The novel coronavirus disease-2019 (COVID-19), caused by the severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2), has become a public health emergency of international concern. The first confirmed COVID-19 case in Indonesia was announced on 2 March 2020, and later on, 11,192 confirmed cases were reported as of 3 May. The World Health Organization has stated that performing a real-time reverse transcription–polymerase chain reaction (RT-PCR) specific for SARS-CoV-2 on specimens from the upper and the lower respiratory tracts, especially nasopharyngeal and oropharyngeal swabs, is the standard diagnostic procedure for COVID-19. In Indonesia, we also use other diagnostic tests, such as rapid antibody tests specific for SARS-CoV-2. Herein, we report an atypical case of COVID-19 and describe the diagnostic process, the clinical course, with progression to severe pneumonia on Week 3 of illness and the case management. We also try to highlight the possibility of false-negative RT-PCR tests.

Palabras clave

  • COVID-19
  • SARS-CoV-2
  • RT-PCR
  • atypical case
  • sero-positive

Cuvinte-cheie

  • COVID-19
  • SARS-COV2
  • RT-PCR
  • Caz atipic
  • Seropozitiv

Smoking Problems

Acceso abierto

COVID 19 - a new threat for smokers and vapers?

Publicado en línea: 31 Dec 2020
Páginas: 115 - 118

Resumen

Abstract

The new pandemic disease Covid-19 compelled all the researchers to investigate for early identification of the potential risk factors. Further, the relation between smoking and infections are well known. The authors are trying to find the epidemiological links, the pathogenic mechanisms and also the impact of this coronavirus on different respiratory chronic diseases, based on the last published data about the consequences of smoking and vaping on consumers.

Palabras clave

  • vaping
  • e cigarette
  • smoking
  • COVID-19

Cuvinte-cheie

  • vaping
  • tigara electronică
  • fumatul
  • COVID-19
Acceso abierto

No Tobacco Day 2020 – another ancient ‘COVID DAY’?

Publicado en línea: 31 Dec 2020
Páginas: 119 - 121

Resumen

Romanian Society of Pneumology Activities

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