<abstract xmlns="http://www.w3.org/1999/xhtml"><sec id="j_1905-7415.0904.419_s_001_w2aab3b7b6b1b6b1aab1c16b1Aa"><h3>Background</h3><p>soriasis is an independent risk factor for cardiovascular disease. Several tools such as Framingham score (FRS) and Ramathibodi-Electricity Generating Authority of Thailand (RAMA-EGAT) score have been developed to predict the 10-year risk of coronary artery disease (CAD) and death. However, there are only few studies determine CAD risk using FRS and RAMA-EGAT score in Asian patients with psoriasis.</p></sec><sec id="j_1905-7415.0904.419_s_002_w2aab3b7b6b1b6b1aab1c16b2Aa"><h3>Objectives</h3><p>To investigate the risk of CAD events using the FRS and RAMA-EGAT score in Thai patients with psoriasis.</p></sec><sec id="j_1905-7415.0904.419_s_003_w2aab3b7b6b1b6b1aab1c16b3Aa"><h3>Methods</h3><p>Predictive factors that associated with intermediate and high risk (≥10%) of CAD events within 10-year were determined. Variables, including age, sex, blood pressure, cholesterol, high-density lipoprotein, diabetes mellitus, waist circumference, smoking, and alcohol intake were used to calculate scores.</p></sec><sec id="j_1905-7415.0904.419_s_004_w2aab3b7b6b1b6b1aab1c16b4Aa"><h3>Results</h3><p>Of 145 patients with psoriasis and a mean age of 48.1 ± 14.1 years, 72 patients were men. Using FRS and RAMA-EGAT, 25% and 13% of the patients, respectively had a ≥10% risk of developing CAD events. A higher risk of CAD was predicted when severe psoriasis was considered. The duration of disease and treatment were associated with an increased risk of CAD using the FRS and RAMA-EGAT score by multivariate analysis.</p></sec><sec id="j_1905-7415.0904.419_s_005_w2aab3b7b6b1b6b1aab1c16b5Aa"><h3>Conclusions</h3><p>A substantial portion of our patients had a CAD risk ≥10%, with significant relationship with duration of disease and treatment. Early screening of CAD and appropriate treatments of psoriasis may be helpful for preventing CAD in patients with psoriasis.</p></sec></abstract>

Backgroundsoriasis is an independent risk factor for cardiovascular disease. Several tools such as Framingham score (FRS) and Ramathibodi-Electricity Generating Authority of Thailand (RAMA-EGAT) score have been developed to predict the 10-year risk of coronary artery disease (CAD) and death. However, there are only few studies determine CAD risk using FRS and RAMA-EGAT score in Asian patients with psoriasis.ObjectivesTo investigate the risk of CAD events using the FRS and RAMA-EGAT score in Thai patients with psoriasis.MethodsPredictive factors that associated with intermediate and high risk (≥10%) of CAD events within 10-year were determined. Variables, including age, sex, blood pressure, cholesterol, high-density lipoprotein, diabetes mellitus, waist circumference, smoking, and alcohol intake were used to calculate scores.ResultsOf 145 patients with psoriasis and a mean age of 48.1 ± 14.1 years, 72 patients were men. Using FRS and RAMA-EGAT, 25% and 13% of the patients, respectively had a ≥10% risk of developing CAD events. A higher risk of CAD was predicted when severe psoriasis was considered. The duration of disease and treatment were associated with an increased risk of CAD using the FRS and RAMA-EGAT score by multivariate analysis.ConclusionsA substantial portion of our patients had a CAD risk ≥10%, with significant relationship with duration of disease and treatment. Early screening of CAD and appropriate treatments of psoriasis may be helpful for preventing CAD in patients with psoriasis.

Coronary artery events in Thai patients with psoriasis using Framingham and Ramathibodi–Electricity Generating Authority of Thailand risk scores

Department of Dermatology, Faculty of Medicine

Department of Internal Medicine, Faculty of Medicine

Asian Biomedicine

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Backgroundsoriasis is an independent risk factor for cardiovascular disease. Several tools such as Framingham score (FRS) and Ramathibodi-Electricity...

Coronary artery events in Thai patients with psoriasis using Framingham and Ramathibodi–Electricity Generating Authority of Thailand risk scores

Article Category: Brief communication (Original)

Publicado en línea: 31 ene 2017

Páginas: 495 - 500

DOI: https://doi.org/10.5372/1905-7415.0904.419

Palabras clave
Coronary artery diseases, Framingham score, psoriasis, RAMA-EGAT score, Thai

© 2015 Sakunee Khankham, Leena Chularojanamontri, Chanisada Wongpraparut, Narumol Silpa-archa, Nuttaporn Janyong, Prin Vathesatogkit

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Coronary artery events in Thai patients with psoriasis using Framingham and Ramathibodi–Electricity Generating Authority of Thailand risk scores

Article Category: Brief communication (Original)

Publicado en línea: 31 ene 2017

Páginas: 495 - 500

DOI: https://doi.org/10.5372/1905-7415.0904.419

Palabras claveCoronary artery diseases, Framingham score, psoriasis, RAMA-EGAT score, Thai

© 2015 Sakunee Khankham, Leena Chularojanamontri, Chanisada Wongpraparut, Narumol Silpa-archa, Nuttaporn Janyong, Prin Vathesatogkit

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Palabras clave
Coronary artery diseases, Framingham score, psoriasis, RAMA-EGAT score, Thai