OR | 95% Confidence interval for OR | ||
---|---|---|---|
<453 | 1.00 | 1.00 | |
453–906 | 0.64 | 0.36–1.13 | 0.12 |
>906 | 9.29 | 1.24–69.56 | 0.03 |
Normal weight | 1.00 | 1.00 | |
Overweight | 1.12 | 0.48–2.62 | 0.79 |
Obese | 3.42 | 1.18–9.95 | 0.02 |
Body mass index | |||||
---|---|---|---|---|---|
Normal (n = 724) | Overweight (n = 31) | Obese (n = 39) | Normal vs overweight | Normal vs obese | |
Urinary bisphenol A (ng/mL) | 0.67 | 0.62 | 0.87 | 0.63 | 0.14 |
Adjusted bisphenol A (μg/g Cr) | 0.51 | 0.36 | 0.71 | 0.30 | 0.19 |
n (%) | Urinary bisphenol A (n, %) | |||
---|---|---|---|---|
<0.05 ng/mL | ≥0.05 ng/mL | |||
3.01-6.00 | 40 (10.6) | 15 (16.2) | 25 (32.5) | 0.048 |
6.01-10.00 | 146 (38.8) | 39 (41.9) | 29 (37.7) | 0.479 |
10.01-18.00 | 190 (50.6) | 39 (41.9) | 23 (29.8) | 0.056 |
Male | 193 (51.3) | 41 (44.1) | 152 (53.7) | 0.121 |
Female | 183 (48.7) | 52 (55.9) | 131 (46.3) | 0.121 |
<453 | 273 (74.0) | 68 (73.9) | 205 (74.0) | 0.899 |
453–906 | 67 (18.2) | 23 (25.0) | 44 (15.9) | 0.045 |
>906 | 29 (7.8) | 1 (1.1) | 28 (10.1) | 0.006 |
Normal weight | 274 (79.7) | 77 (86.5) | 197 (77.3) | 0.015 |
Overweight | 31 (9.0) | 8 (9.0) | 23 (9.0) | 0.831 |
Obese | 39 (11.3) | 4 (4.5) | 35 (13.7) | 0.030 |
Authors | Country | Year | Ν | Age | Method | Limit of detection (ng/mL) | Bisphenol A (ng/mL) | Obesity (%) | Over-weight (%) | Bisphenol A (ng/mL) and obesity | |
---|---|---|---|---|---|---|---|---|---|---|---|
2011 Carwile XL, et al [ | USA | 2003-2006 | 2,747 | 18-74 | LCMS | 0.3 | 2.05 (median) | 33.9 | lstQ(BPA<l.l) | Significant, 95%CI | |
2nd Q (1.2-2.3) | |||||||||||
3rd Q (2.4–1.6) | |||||||||||
4th Q (>4.7) | |||||||||||
OR 1.60-1.85 | |||||||||||
2012 Trasande L, et al [ | USA | 2003-2008 | 2838 | 6-19 | LCMS | 0.3 | 2.8 (median) | 17.8 | 34.1 | lstQ(BPA≤1.5) | < 0.001 |
2nd Q (1.5-2.7) | |||||||||||
3rd Q (2.8-5.5) | |||||||||||
4thQ(>5.6) | |||||||||||
OR 2.08-2.57 | |||||||||||
2012 Bhandari R, et al [ | USA | 2003-2008 | 2200 | 6-18 | LCMS | 0.3 | 4.8 | 17.7 | 16.7 | lstQ(BPA≤1.5) | 0.002 |
2nd Q (1.5-2.7) | |||||||||||
3rd Q (2.8-5.4) | |||||||||||
4thQ(>5.4) | |||||||||||
OR 1.78-2.55 | |||||||||||
2012 Wang H, et al [ | China | 2011 | 259 | 8-15 | LCMS | 0.07 | 0.45 GM | 31.7 | 20.4 | Normal BPA 0.33 Obesity BPA 0.57 | 0.018 |
2013 Li D, et al [ | China | 2011 | 1,326 | 4-12 | HPL/FD | 0.31 | NA | 18.3 | girl: associated with overweight | Significant, 95%CI | |
Characteristics | Adjusted urinary bisphenol A (μg/g Cr) | Estimated daily intake (μg/day) | ||
---|---|---|---|---|
Mean ± S D | Median (IQR) | Mean ± S D | Median (IQR) | |
3.01-6.00 | 1.21 ± 1.53 | 0.70 (0-1.90) | 0.55 ± 0.79 | 0.28 (0-0.66) |
6.01-10.00 | 0.97 ± 1.43 | 0.71 (0-1.10) | 0.67 ± 0.86 | 0.43 (0-0.87) |
10.01-18.00 | 0.78 ± 1.07 | 0.45 0.13-0.98) | 1.42 ± 1.79 | 0.80 (0.18--2.04) |
0.90 ± 1.28 | 0.53 (0.04-1.12) | 1.04 ± 1.46 | 0.55 (0.06-1.48) | |
Male | 0.90 ± 1.09 | 0.54 0.15-1.18) | 1.15 ± 1.49 | 0.60 (0.20-1.54) |
Female | 0.91 ± 1.45 | 0.50 (0-1.02) | 0.92 ± 1.41 | 0.44 (0-1.09) |
<453 | 0.88 ± 1.15 | 0.53 (0.04-1.14) | 0.99 ± 1.36 | 0.55 (0.040-1.25) |
453-906 | 0.74 ± 0.97 | 0.41 (0-0.97) | 1.09 ± 1.86 | 0.35 (0-1.43) |
>906 | 1.59 ± 2.44 | 0.71 (0.35-0.31) | 1.46 ±1.35 | 0.76 (0.41--.34) |
Normal weight | 0.91 ± 1.35 | 0.51 (0-1.09) | 0.98 ± 1.39 | 0.50 (0-1.32) |
Overweight | 0.65 ± 0.96 | 0.36 (0-0.76) | 1.14 ± 2.18 | 0.45 (0-1.03) |
Obese | 0.90 ± 1.03 | 0.71 (0.21.16) | 1.24 ± 1.43 | 0.65 (0.30-0.04) |