Pathologically-based positive lymph node ratio (pLNR) for stage III colorectal cancer patients: prognostic impact on cases with fewer than 12 lymph node retrievals

1. Edge SB, Byrd DR, Compton CC, Fritz AG, Greene FL, Trotti A (Eds.). American Joint Committee on Cancer (AJCC) Cancer Staging Manual. 7th ed. New York: Springer; 2009.Search in Google Scholar

2. Sobin LH, Gospodarowicz MK, Wittekind Ch, eds. International Union Against Cancer (UICC) TNM Classification of Malignant Tumors. 7th ed. Oxford, UK: Wiley-Blackwell; 2009.Search in Google Scholar

3. Nelson H, Petrelli N, Carlin A, Couture J, Fleshman J, Guillem J, et al. Guidelines 2000 for colon and rectal cancer surgery. J Natl Cancer Inst. 2001; 93:583-96.10.1093/jnci/93.8.58311309435Open DOISearch in Google Scholar

4. Washington MK, Berlin J, Branton P, Burgart LJ, Carter DK, Fitzgibbons PL, et al. Protocol for the examination of specimens from patients with primary carcinomas of the colon and rectum. Arch Pathol Lab Med. 2009;133:1539-51.10.5858/133.10.1539290183819792043Search in Google Scholar

5. Yildirim E, Berberoglu U. Lymph node ratio is more valuable than level III involvement for prediction of outcome in nodepositive breast carcinoma patients. World J Surg. 2007; 31:276-89.10.1007/s00268-006-0487-517219275Open DOISearch in Google Scholar

6. Marchet A, Mocellin S, Ambrosi A, de Manzoni G, Di Leo A, Marrelli D, et al. The prognostic value of N ratio in patients with gastric cancer: validation in a large, multicenter series. Eur J Surg Oncol. 2008; 34: 159-65.10.1016/j.ejso.2007.04.01817566691Open DOISearch in Google Scholar

7. Herr H. Superiority of ratio based lymph node staging for bladder cancer. J Urol. 2003; 169:943-5.10.1097/01.ju.0000032474.22093.0612576818Search in Google Scholar

8. Berger AC, Watson JC, Ross EA, Hoffman JP. The metastatic examined lymph node ratio is an important prognostic factor after pancreaticoduodenectomy for pancreatic adenocarcinoma. Am Surg. 2004; 70: 235-40.10.1177/000313480407000309Search in Google Scholar

9. Berger AC, Sigurdson ER, LeVoyer T, Hanlon A, Mayer RJ, Macdonald JS, et al. Colon cancer survival is associated with decreasing ratio of metastatic to examined lymph nodes. J Clin Oncol. 2005; 23:8706-12.10.1200/JCO.2005.02.885216314630Open DOISearch in Google Scholar

10. De Ridder M, Vinh-Hung V, Van Nieuwenhove Y, Hoorens A, Sermeus A, Storme G. Prognostic value of the lymph node ratio in node positive colon cancer. Gut. 2006; 55:1681.10.1136/gut.2006.104117186009117047131Open DOISearch in Google Scholar

11. Wang J, Hassett JM, Dayton MT, Kulaylat MN.L ymph node ratio: role in the staging of node-positive colon cancer. Ann Surg Oncol. 2008; 15:1600-8.10.1245/s10434-007-9716-x18327530Open DOISearch in Google Scholar

12. Schumacher P, Dineen S, Barnett C Jr, Fleming J, Anthony T. The metastatic lymph node ratio predicts survival in colon cancer.AmJ Surg. 2007; 194:827-32.10.1016/j.amjsurg.2007.08.03018005779Search in Google Scholar

13. Lee HY, Choi HJ, Park KJ, Shin JS, Kwon HC, Roh MS, et al. Prognostic significance of metastatic lymph node ratio in node positive colon carcinoma. Ann Surg Oncol. 2007; 14:1712-7.10.1245/s10434-006-9322-317253102Open DOISearch in Google Scholar

14. Klos CL, Bordeianou LG, Sylla P, Chang Y, Berger DL. The prognostic value of lymph node ratio after neoadjuvant chemoradiation and rectal cancer surgery. Dis Colon Rectum. 2011; 54:171-5.10.1007/DCR.0b013e3181fd677d21228664Open DOISearch in Google Scholar

15. Moug SJ, Saldanha JD, McGregor JR, Balsitis M, Diament RH. Positive lymph node retrieval ratio optimises patient staging in colorectal cancer. Br J Cancer. 2009; 100:1530-3.10.1038/sj.bjc.6605049269675519401684Open DOISearch in Google Scholar

16. Chang GJ, Rodriguez-Bigas MA, Skibber JM, Moyer VA. Lymph node evaluation and survival after curative resection of colon cancer: systematic review. J Natl Cancer Inst. 2007; 99:433-41.10.1093/jnci/djk09217374833Open DOISearch in Google Scholar

17. Baxter NN, Virnig DJ, Rothenberger DA, Morris AM, Jessurun J, Virnig BA. Lymph node evaluation in colorectal cancer patients: a population-based study. J Natl Cancer Inst. 2005; 97:219-25.10.1093/jnci/dji02015687365Open DOISearch in Google Scholar