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Pulse oximetry as a screening test for congenital heart disease in newborns


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Characteristics of the neonatal study population.

Neonatal characteristics N Mean ± SD Range
Maternal Age (years) 1,082 23.54 ± 2.80 19–32
Gestational Age (weeks) 1,082 39.41 ± 1.33 37–41
Hours of Life 1,082 8.30 ± 2.85 4–22
Birth Weight (Kg) 1,082 2.72 ± 0.124 2.5–3.2
Heart Rate (beats per minute) 1082 151 ± 13 120–168
Respiratory Rate (rate/ min) 1,082 43.5 ± 5 38–58
SpO2 (in %) First Reading (R1) 1,062 97 ± 1 95–100
18 93 ± 1 92–94
2 86 ± 1 85–87
SpO2 (in %) Second Reading (R2) 15 96 ± 1 96–100
3 93 ± 1 92–94
SpO2 (in %) Third Reading (R3) 15 97 ± 1 96–100
3 93 ± 1 92–94

Group-wise distribution of neonates in the study.

Groups Frequency Percentage
Birth Weight 2.5 to 3 Kgs 1,021 94.4
3.1 to 4 Kgs 61 5.6
Sex Female 513 47.4
Male 569 52.6
Heart Rate (beats / min) 120 to 140 183 16.9
141 to 160 733 67.7
161 to 180 166 15.3
Respiratory Rate (per minute) 38 to 47 821 75.9
48 to 58 261 24.1
Hours of Life at Pulse oximetry Evaluation 2 to 6 hours 324 29.9
6 to 12 hours 693 64.0
12 to 24 hours 65 6.0
Total 1,082 100.0

Distribution of Maternal Characteristics

Maternal characteristics Group Frequency Percentage
Maternal Age (years) ≤ 20 108 10.0
21 to 25 597 55.2
26 to 30 342 31.6
> 30 35 3.2
Gestational Age (weeks) 37 97 9
38 344 31.7
39 348 29.4
40 217 20.1
41 106 9.8
Registration Status Non-registered 425 39.3
Registered 657 60.7
H/O Diabetes No 1,079 99.7
Yes 3 0.3
Mode of Delivery Normal 842 77.8
LSCS 240 22.2
Infections during pregnancy No 1,045 96.6
URTI 19 1.8
Malaria 8 0.7
Torch 6 0.6
Hepatitis 4 0.4
Total 1,082 100.0

Oxygen Saturation (SpO2) by Pulse Oximeter

SpO2 Groups Frequency Percentage
1st Reading (R1) ≥ 95% 1,062 98.1
90%–94% 18 1.7
< 90% 2 0.2
Total 1,082 100.0
1st Repeat (R2) ≥ 95% 15 83.3
90%–94% 3 16.7
Total 18 100.0
2nd Repeat (R3) ≥ 95% 15 83.3
90%–94% 3 16.7
Total 18 100.0

Saturation and presentation of newborns suspected of having critical CHD.

Sr. No SpO2 (%) Subsequent SpO2 (%) Neonatal Presentation Suspected By 2D ECHO Diagnosis
1 87 90 Grade 3, Systolic murmur POx and Clinical Examination TGA + VSD
2 85 87 Grade 4, Ejection systolic murmur at left upper parasternal region POx and Clinical Examination TOF
3 92 92 Normal Pox DORV
4 92 92 Normal Pox ASD + PH
5 95 96 Bounding pulse, Grade 4, continuous murmur, left infra-clavicular region Clinical Examination PDA
6 94 94 Asymptomatic POx Normal
7 100 Grade 2 systolic murmur Clinical Examination Normal
8 98 Grade 2 systolic murmur Clinical Examination Normal
9 97 Grade 2 systolic murmur Clinical Examination Normal
10 100 Grade 2 systolic murmur Clinical Examination Normal
eISSN:
2719-535X
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